Research Themes
Define molecular and cellular mechanisms of immune-regulation, targets and lead molecules and harness them to design new strategies restoring immune homeostasis to prevent and treat infectious, inflammatory diseases and cancers.
Define molecular and cellular mechanisms of immune-regulation, targets and lead molecules and harness them to design new strategies restoring immune homeostasis to prevent and treat infectious, inflammatory diseases and cancers.
Team Leads
Dr Chen Kaiwen
Coordinator
Key Areas of Research
- Innate immunity and inflammation
- Programmed cell death
- Host-pathogen interactions
Team Members
Dr Benoit Malleret
Key Areas of Research
- Human and zoonotic malaria
- Gut microbiome dysbiosis
- Electron microscopy
A/Prof Chen Jinmiao
Key Areas of Research
- Single-cell omics, Spatial omics, AI, Immunology.
- Developing novel analytical methods and databases for the integration and analyses of single-cell and spatial omics data.
Dr Jonathan Lee Wei Jie
Key Areas of Research
- Investigating the role of the gut microbiome in gastrointestinal cancers.
- Develop predictive microbial markers and targeted therapies for gastrointestinal cancers.
A/Prof Lina Lim Hsiu Kim
Key Areas of Research
- Annexin-A1
- Macrophages and Dendritic cells in the Tumor microenvironment
- Impact of Stress on cancer and inflammation
A/Prof Lu Jinhua
Key Areas of Research
- Cancer vaccines: antigens & adjuvants
- Systemic lupus erythematosus (SLE): alarmins & autoantibodies
- Complement: C1q & C1 proteases
A/Prof Nguyen Nam Long
Key Areas of Research
- Sphingosine-1-phosphate transport and signaling
- Nutrient transport at blood-brain barrier
- Lysosomal transport pathways for small molecules
- Lysolipid transport and functions
Dr Peh Hong Yong
Key Areas of Research
- Resolution of inflammation
- Pro-resolving lipid mediators (lipoxins, resolvins, maresins, protectins) and eicosanoids
- Inflammation and inflammaging
- Macrophage efferocytosis
Dr Tay Sen Hee Frank
Key Areas of Research
- Systemic lupus erythematosus
- Nonsteroidal anti-inflammatory drug hypersensitivity
- Immune-related adverse effects
- Neutrophils
- Epigenetics