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Postnatal deletion of Spns2 prevents neuroinflammation without compromising blood vascular functions

Posted on: November 11, 2022

Multiple Sclerosis (MS) is a debilitating disease with few therapeutic options. Sphingosine-1-phosphate (S1P) is a potent lipid mediator secreted by several cell types and is involved in several important biological pathways. Assistant Prof Nguyen Nam Long collaborated with A/Prof Veronique Angeli and A/Prof Zhang Yongliang in a study which showed the targeting of S1P transporters could be a potential therapeutic target in treating MS and other neuroinflammatory diseases.

https://link.springer.com/article/10.1007/s00018-022-04573-y

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Postnatal deletion of Spns2 prevents neuroinflammation without compromising blood vascular functions

Multiple Sclerosis (MS) is a debilitating disease with few therapeutic options. Sphingosine-1-phosphate (S1P) is a potent lipid mediator secreted by

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