Research Highlights
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CD28-CAR-T cell activation through FYN kinase signaling rather than LCK enhances therapeutic performance
6 February 2023
CAR-T therapy is often very costly and not effective in killing solid tumours. Prof Nicholas Gasco ...
Postnatal deletion of Spns2 prevents neuroinflammation without compromising blood vascular functions
11 November 2022
Multiple Sclerosis (MS) is a debilitating disease with few therapeutic options. Sphingosine-1-phosph ...
Defining the specificity and function of a human neutralizing antibody for Hepatitis B virus
8 November 2022
Did you know that around 1 in 25 people in Singapore have chronic hepatitis B infection? Infection o ...
Distinct transcriptomic and metabolomic profiles characterize NSAID-induced urticaria/angioedema patients undergoing aspirin desensitization
22 August 2022
Most of us have probably taken a nonsteroidal anti-inflammatory drug (NSAID) such as ibuprofen, mefe ...
Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock
18 August 2022
Stroke is one of the leading causes of death in Singapore, with hemorrhagic stroke being the most de ...
Lower vaccine-acquired immunity in the elderly population following two-dose BNT162b2 vaccination is alleviated by a third vaccine dose
16 August 2022
COVID-19 vaccines have been shown to reduce mortality and complications due to SARS-COV-2. However, ...