IMPACT 2

NMRC Collaborative Centre Grant (CCG)
Researchers inflating a balloon catheter​

Team

Arthur Mark Richards, Chester Drum, Roger Foo, Mark Chan, Ronald Lee Chi Hang

Collaborating Institutions

National Heart Centre Singapore

Project

This is a NMRC Collaborative Centre Grant (CCG) which is shared between the 2 national heart centres (NHCS, NUHCS) and the National Healthcare Group Heart Institute  (NHGHI).

It comprises of 4 cores:

This core unifies common processes and procedures to ensure consistency and facilitate collaboration, merging the Genomics and Biomarkers facility cores established by the IMPACT-1 CCG, and adding a new capability to undertake metabolomics analysis. Support from this core will analyse samples jointly collected in clinical studies recruiting patients across National Heart Centre Singapore (NHCS), National University Heart Centre, Singapore (NUHCS) and the National Healthcare Group Heart Institute (NHGHI).

This facility core was established by IMPACT-1 CCG to provide Clinical Research Coordinator (CRC) support to recruit patients for clinical studies. For the IMPACT-2 CCG renewal, this core will be extended to include NHGHI, thereby enabling nationwide patient recruitment for clinical studies running across the 3 campuses (NHCS, NUHCS and NHGRI).
The IMPACT-1 CCG established the Echo and Cardiac MRI facility cores across NHCS and NUHCS. In IMPACT-2 CCG, we have added a new facility core for standardised analysis of Cardiac CT studies. In order to unify some common processes and procedures to ensure consistency and facilitate collaboration. This merges the Echo, Cardiac MRI and new Cardiac CT cores into a single multimodality cardiac imaging core. Support from this newly merged core is extended to NHGHI in order to provide standardised core laboratory analyses of Echo, Cardiac MRI and Cardiac CT studies undertaken in clinical studies recruiting patients across NUHCS, NHCS and NHGHI.
The cardiosleep research laboratory, located at the NUHCS cardiac rehabilitation centre, has facilitated the conduct of overnight sleep studies by using the AASM (American Academy of Sleep Medicine) level-3 portable device to the AASM level-1 in-laboratory polysomnography (the gold standard).