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Newsletter

Member, MOH Heat Stress Guidelines Expert Panel New LT Organization Structure

Research Associate Professor Jason Lee has been appointed as member of the MOH Heat Stress Guidelines Expert Panel.

With effect from 1 May 2021, the Department will be adopting a new Lab Technologists organization structure under the oversight of Associate Professor Herbert Schwarz and Dr. Ivan Low.

Appreciation Wall

Professor Reshma Taneja, Associate Professor Herbert Schwarz and Dr Ivan Low have put up an appreciation wall for everyone to put up notes of appreciation and encouragement for members of the department. This wall is located in MD9 level 4 behind the pantry and conference room.

 

Yong Loo Lin School of Medicine Researcher of the Year Award and Research Excellence Award AY2019/2020 Yong Loo Lin School of Medicine Graduate Mentor of the Year (GRAMAY) Award 2021

Professor Hanry Yu has been selected to receive the Yong Loo Lin School of Medicine Researcher of the Year Award; and Assistant Professor John Chua has been selected to receive the Research Excellence Award for AY2019/2020. Congratulations to both of them!

Associate Professor Saji Kumar Sreedharan won Yong Loo Lin School of Medicine Graduate Mentor of the Year (GRAMAY) Award 2021. Congratulations A/Professor Saji!

Yong Loo Lin School of Medicine Teaching Excellence Award (Individual) AY 2019/2020 Yong Loo Lin School of Medicine Best Graduate Research Publication Award 2021

Associate Professor Sanjay Khanna and Associate Professor Saji Kumar Sreedharan has been awarded the Yong Loo Lin School of Medicine Teaching Excellence Award (Individual) for AY 2019/2020. Congratulations to both of them!

Yong Loo Lin School of Medicine Best Graduate Research Publication Award 2021. Congratulations Dr. Sundar!

Raghav Sundar
PhD. Physiology, 1st Author
Publication Title: Spatial profiling of gastric cancer patient-matched primary and locoregional metastases reveals principles of tumor dissemination
Journal: Gut
Supervisor: Professor Tan Boon Ooi, Patrick

2021 Swee Liew-Wadsworth Grants 2021 Science Pitch Day

Winners of the 2021 Swee Liew-Wadsworth Grants. Congratulations to all awardees!

Intra-departmental Grants:
Zakaria Ali Moh Almsherqi [Education]
Karen Crasta & Mahmoud Pouladi
Karthik Mallilankaraman & Manoor Prakash Hande
Shazib Pervaiz & Derrick Ong

Concept Grants:
Hannelore Hartmann (Shuo-Chien Ling Lab)
Chua You Heng (Derrick Ong Lab)
Dipanwita Das (Reshma Taneja Lab)
Lily Anna Henry (Mahmoud Pouladi Lab)
Sim Wei Liang (Thai Tran Lab)
Alamelu Nachiyappan (Reshma Taneja Lab)
Wong Lik Wei (Sajikumar Sreedharan Lab)
Karishma Sachaphibulkij (Lina Lim Lab)
Basil Kuah Zheng Mian (Shuo-Chien Ling Lab)
Kagistia Hana Utami (Mahmoud Pouladi Lab)
Angeline Liew Qiu Xia (Shazib Pervaiz Lab)
Deng Shuo (Celestial Yap Lab)

Winners of 2021 Science Pitch Day Award. Congratulations to all awardees!

Best Pitch Award:
Best Presentation: Loh Wei Zhern Kelvin (Soong Tuck Wah Lab)
1st Runner Up: Nandini Karthik (Reshma Taneja Lab)
2nd Runner Up: Choo Zhang’E (Hooi Shing Chuan/Chen Zhi Xiong Lab)
People’s Choice Award: Elisa Marie Crombie (Tsai Shih-Yin Lab)

Concept Grant Presentation Awards (in no particular order):
Angeline Liew Qiu Xia (Shazib Pervaiz Lab)
Lily Anna Henry (Mahmoud Pouladi Lab)
Sim Wei Liang (Thai Tran Lab)

Long Service Award

Congratulations to all recipients of Long Service Award 2020 and 2021.

Promoted to Associate Professor Promoted to Senior Assistant Manager

Senior Lecturer Chen Zhi Xiong has been promoted to Associate Professor (Educator Track) with effect from January 1, 2021. Congratulations A/Professor Chen!

Chan Bixiu, Michelle has been promoted to Senior Assistant Manager with effect from July 1, 2021. Congratulations Michelle!

Prof Hanry Yu featured in The Straits Times A/Prof Jason Lee featured in MEDSPRESSO ad National Geographic

Professor Hanry Yu was featured in The Straits Times for his group's development of a more precise, faster and cheaper method of detecting numerous viruses.
The Straits Times Article

Research Associate Professor Jason Lee was featured in MEDSPRESSO and National Geographic for his research work on how the body handles heat via an infographic.
Feature in MEDSPRESSO
Full Article in National Geographic

Health-Promoting Cities EOCD & WISH Lunch and Learn 2021: Building A Great And Inclusive Place To Work - Sharing From Our HODs


Research Associate Professor Jason Lee gave a talk in Health-Promoting Cities webinar on 27 April 2021.

Professor Reshma Taneja served as a panelist on "EOCD & WISH Lunch and Learn 2021: Building A Great And Inclusive Place To Work - Sharing From Our HODs" event on 30 Jun 2021.
View Photo here

FEZ1 Forms Complexes with CRMP1 and DCC to Regulate Axon and Dendrite Development
Jie Yin Chua, Shi Jun Ng, Oleksandr Yagensky, Erich E. Wanker and John Jia En Chua
eNeuro 26 March 2021, 8 (2) ENEURO.0193-20.2021; doi: 10.1523/ENEURO.0193-20.2021
Full Text

Cytoskeletal Dynamics in Epithelial-Mesenchymal Transition: Insights into Therapeutic Targets for Cancer Metastasis
Arpita Datta, Shuo Deng, Vennila Gopal, Kenneth Chun-Hong Yap, Clarissa Esmeralda Halim, Mun Leng Lye, Mei Shan Ong, Tuan Zea Tan, Gautam Sethi, Shing Chuan Hooi, Alan Prem Kumar and Celestial T. Yap
Cancers 2021, 13(8), 1882; doi: 10.3390/cancers13081882
Abstract

Mitochondrial Dysfunction in Age-Related Metabolic Disorders
Venkateswaran Natarajan Ritu Chawla, Tania Mah, Rajesh Vivekanandan, Shu Yi Tan, Priscila Y Sato, Karthik Mallilankaraman
Proteomics. 2020 Mar;20(5-6):e1800404. doi: 10.1002/pmic.201800404. Epub 2020 Mar 17.
Abstract

Epigenetic regulation of microglial phosphatidylinositol 3-kinase pathway involved in long-term potentiation and synaptic plasticity in rats
Genevieve Saw, Kumar Krishna, Neelima Gupta, Tuck Wah Soong, Karthik Mallilankaraman, Sreedharan Sajikumar, S Thameem Dheen
Glia. 2020 Mar;68(3):656-669. doi: 10.1002/glia.23748. Epub 2019 Nov 8.
Full Text

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)
David J Klionsky….Karthik Mallilankaraman et al
Autophagy. 2021 Jan;17(1):1-382. doi: 10.1080/15548627.2020.1797280. Epub 2021 Feb 8.
Abstract

Oxygen Glucose Deprivation Induced Prosurvival Autophagy Is Insufficient to Rescue Endothelial Function
Venkateswaran Natarajan, Tania Mah, Chen Peishi, Shu Yi Tan, Ritu Chawla, Thiruma Valavan Arumugam, Adaikalavan Ramasamy, Karthik Mallilankaraman
Front Physiol. 2020 Sep 16;11:533683. doi: 10.3389/fphys.2020.533683. eCollection 2020.
Full Text

Dynamic contrast-enhanced MRI of brown and beige adipose tissues
Jadegoud Yaligar, Sanjay Kumar Verma, Venkatesh Gopalan, Rengaraj Anantharaj, Giang Thi Thu Le, Kavita Kaur, Karthik Mallilankaraman, Melvin Khee-Shing Leow, S Sendhil Velan
Magn Reson Med. 2020 Jul;84(1):384-395. doi: 10.1002/mrm.28118. Epub 2019 Dec 4.
Abstract

miR-142-3p Regulates BDNF Expression in Activated Rodent Microglia Through Its Target CAMK2A
Neelima Gupta, Shweta Jadhav, Kai-Leng Tan, Genevieve Saw, Karthik Babu Mallilankaraman, S Thameem Dheen
Front Cell Neurosci. 2020 May 21;14:132. doi: 10.3389/fncel.2020.00132. eCollection 2020.
Full Text

ER-luminal [Ca 2+] regulation of InsP 3 receptor gating mediated by an ER-luminal peripheral Ca 2+-binding protein
Horia Vais, Min Wang, Karthik Mallilankaraman, Riley Payne, Chris McKennan, Jeffrey T Lock, Lynn A Spruce, Carly Fiest, Matthew Yan-Lok Chan, Ian Parker, Steven H Seeholzer, J Kevin Foskett, Don-On Daniel Mak
Elife. 2020 May 18;9:e53531. doi: 10.7554/eLife.53531.
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Three-Dimensional Macroporous Sponge for the Culture of Hepatocellular Carcinoma Patient-Derived Xenograft Organoids
Tan Boon Toh, Zheng Liu, Hanry Yu, Eliza Li Shan Fong
SLAS Technology, (2021), First Published March 27, 2021. doi: 10.1177/24726303211000685.
Full Text

Isolation of Primary Rat Hepatocytes with Multiparameter Perfusion Control
Inn Chuan Ng, Li Zhang, Narelle Nichola Yi Ying Shen, Yun Ting Soong, Chan Way Ng, Phoebe Kang Sheing Koh, Yan Zhou, Hanry Yu
J Vis Exp. 2021 Apr 5;(170). doi: 10.3791/62289.
Full Text

Hydrogel-based colorectal cancer organoid co-culture models
Xiaobei Luo, Eliza Li Shan Fong, Chaojun Zhua, Quy Xiao Xuan Lin, Man Xiong, Aimin Li, Tingting Li, Touati Benoukr, Hanry Yu, Side Liu
Acta Biomaterialia, (2021), Available online 31 December 2020. doi: 10.1016/j.actbio.2020.12.037.
Abstract

Digital CRISPR-based method for the rapid detection and absolute quantification of nucleic acids
Xiaolin Wu, Joshua K. Tay, Chuan Keng Goh, Cheryl Chan, Yie Hou Lee, Stacy L. Springs, De Yun Wang, Kwok Seng Loh, Timothy K. Lu, Hanry Yu
Biomaterials. Volume 274, July 2021, 120876. doi: 10.1016/j.biomaterials.2021.120876.
Full Text

A Scalable and Sensitive Steatosis Chip with Long-Term Perfusion of in situ Differentiated HepaRG Organoids
Yao Teng, Zixuan Zhao, Farah Tasnim, Xiaozhong Huang, HanryYu
Biomaterials. Available online 1 June 2021, 120904. doi: 10.1016/j.biomaterials.2021.120904.
Abstract

Design and Fabrication of the Vertical-Flow Bioreactor for Compaction Hepatocyte Culture in Drug Testing Application
Liang Zhu, Zhenfeng Wang, Huanming Xia, and Hanry Yu
Biosensors-Basel, May 2021; 11(5): 160. doi: 10.3390/bios11050160.
Full Text

Recent Advances in Models of Immune-Mediated Drug-Induced Liver Injury
Farah Tasnim, Xiaozhong Huang, Christopher Zhe Wei Lee, Florent Ginhoux and Hanry Yu
Frontiers in Toxicology, 21 April 2021; 3: 6053892. doi: 10.3389/ftox.2021.605392.
Full Text

A Novel Balanced Chromosomal Translocation in an Azoospermic Male: A Case Report
Abhik Chakraborty, Indira Palo, Souvick Roy, Shu Wen Koh, Manoor Prakash Hande, Birendranath Banerjee
J Reprod Infertil. Apr-Jun 2021;22(2):133-137. doi: 10.18502/jri.v22i2.5802.
Abstract

RENEB Inter-Laboratory comparison 2017: limits and pitfalls of ILCs
Eric Gregoire, Joan Francesc Barquinero, Gaetan Gruel, Mohamedamine Benadjaoud, Juan S Martinez, Christina Beinke, Adayabalam Balajee, Philip Beukes, William F Blakely, Inmaculada Dominguez, Pham Ngoc Duy, Octávia Monteiro Gil, Inci Güçlü, Kamile Guogyte, Savina Petrova Hadjidekova, Valeria Hadjidekova, Prakash Hande, Seongjae Jang, Katalin Lumniczky, Roberta Meschini, Mirta Milic, Alegria Montoro, Jayne Moquet, Mercedes Moreno, Farrah N Norton, Ursula Oestreicher, Jelena Pajic, Laure Sabatier, Sylwester Sommer, Antonella Testa, Georgia Terzoudi, Marco Valente, Perumal Venkatachalam, Anne Vral, Ruth C Wilkins, Andrzej Wojcik, Demetre Zafiropoulos, Ulrike Kulka
Int J Radiat Biol. 2021 May 25;1-18. doi: 10.1080/09553002.2021.1928782. Online ahead of print.
Full Text

Investigations on the new mechanism of action for acetaldehyde-induced clastogenic effects in human lung fibroblasts
Varsha Hande, Keith Teo, Prarthana Srikanth, Jane See Mei Wong, Swaminathan Sethu, Wilner Martinez- Lopez, Manoor Prakash Hande
Mutation Research/Genetic Toxicology and Environmental Mutagenesis. Volumes 861–862, January–February 2021, 503303. DOI: 10.1016/j.mrgentox.2020.503303
Abstract

Prediction of the Acute or Late Radiation Toxicity Effects in Radiotherapy Patients Using Ex Vivo Induced Biodosimetric Markers: A Review
Volodymyr Vinnikov, Manoor Prakash Hande, Ruth Wilkins, Andrzej Wojcik, Eduardo Zubizarreta and Oleg Belyakov
Journal of Personalized Medicine, Volume 10, Issue 4. DOI: 10.3390/jpm10040285
Abstract

High glucose alters the DNA methylation pattern of neurodevelopment associated genes in human neural progenitor cells in vitro
Deepika Kandilya, Sukanya Shyamasundar, Dhiraj Kumar Singh, Avijit Banik, Manoor Prakash Hande, Walter Stünkel, Yap Seng Chong & S. Thameem Dheen
Scientific Reports volume 10, Article number: 15676 (2020). DOI: 10.1038/s41598-020-72485-7
Full Text

The redox-senescence axis and its therapeutic targeting
Natalie YL Ngoi, Angeline QX Liew, Stephen J.F. Chong, Matthew S. Davids, Marie-Veronique Clement, Shazib Pervaiz
Redox Biology, Volume 45, September 2021, 102032. DOI: 10.1016/j.redox.2021.102032
Full Text

Establishing intensifying chronic exposure to extreme heat as a slow onset event with implications for health, wellbeing, productivity, society and economy
Elspeth Oppermann, Tord Kjellstrom, Bruno Lemke, Matthias Otto, Jason Kai Wei Lee
Current Opinion in Environmental Sustainability, Volume 50, June 2021, Pages 225-235. DOI: 10.1016/j.cosust.2021.04.006
Full Text

The Impact of Temperature on the Risk of COVID-19: A Multinational Study
Hsiao-Yu Yang and Jason Kai Wei Lee
Int. J. Environ. Res. Public Health 2021, 18(8), 4052. DOI: 10.3390/ijerph18084052
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Hydration Status, Fluid Intake, Sweat Rate, and Sweat Sodium Concentration in Recreational Tropical Native Runners
Juthamard Surapongchai, Vitoon Saengsirisuwan, Ian Rollo, Rebecca K. Randell, Kanpiraya Nithitsuttibuta, Patarawadee Sainiyom, Clarence Hong Wei Leow and Jason Kai Wei Lee
Nutrients 2021, 13(4), 1374. DOI: 10.3390/nu13041374
Full Text

COVID-19 and heat waves: New challenges for healthcare systems
Stephan Bose-O’Reilly, Hein Daanen, Katharina Deering, Nicola Gerrett, Maud Maria Theresia Elisabeth Huynen, Jason Lee, Stefan Karrasch, Franziska Matthies-Wiesler, Hanna Mertes, Julia Schoierer, Joy Shumake-Guillemot, Petervan den Hazel, Joris Adriaan Frank van Loenhout, Dennis Nowak
Environmental Research, Volume 198, July 2021, 111153. DOI: 10.1016/j.envres.2021.111153
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A Web Survey to Evaluate the Thermal Stress Associated with Personal Protective Equipment among Healthcare Workers during the COVID-19 Pandemic in Italy
Alessandro Messeri, Michela Bonafede, Emma Pietrafesa, Iole Pinto, Francesca de’Donato, Alfonso Crisci, Jason Kai Wei Lee, Alessandro Marinaccio, Miriam Levi, Marco Morabito and on behalf of the WORKLIMATE Collaborative Group
Int. J. Environ. Res. Public Health 2021, 18(8), 3861. DOI: 10.3390/ijerph18083861
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Thermal strain and fluid balance during a 72-km military route march in a field setting
Beng Hoong Poon, Suriya Prakaash, Ya Shi Teo, Priscilla Weiping Fan, Jason Kai Wei Lee
Singapore Med J 2021, 1–18. DOI: 10.11622/smedj.2021053
Full Text

Loss of C2orf69 defines a fatal autoinflammatory syndrome in humans and zebrafish that evokes a glycogen-storage-associated mitochondriopathy
Hui Hui Wong, Sze Hwee Seet, Michael Maier, Ayse Gurel, Ricardo Moreno Traspas, Cheryl Lee, Shan Zhang, Beril Talim, Abigail Y T Loh, Crystal Y Chia, Tze Shin Teoh, Danielle Sng, Jarred Rensvold, Sule Unal, Evgenia Shishkova, Ece Cepni, Fatima M Nathan, Fernanda L Sirota, Chao Liang, Nese Yarali, Pelin O Simsek-Kiper, Tadahiro Mitani, Serdar Ceylaner, Ozlem Arman-Bilir, Hamdi Mbarek, Fatma Gumruk, Stephanie Efthymiou, Deniz Uğurlu Çi Men, Danai Georgiadou, Kortessa Sotiropoulou, Henry Houlden, Franziska Paul, Davut Pehlivan, Candice Lainé, Guoliang Chai, Nur Ain Ali, Siew Chin Choo, Soh Sok Keng, Bertrand Boisson, Elanur Yılmaz, Shifeng Xue, Joshua J Coon, Thanh Thao Nguyen Ly, Naser Gilani, Dana Hasbini, Hulya Kayserili, Maha Zaki, Robert J Isfort, Natalia Ordonez, Kornelia Tripolszki, Peter Bauer, Nima Rezaei, Simin Seyedpour, Ghamar Taj Khotaei, Charles C Bascom, Reza Maroofian, Myriam Chaabouni, Afaf Alsubhi, Wafaa Eyaid, Sedat Işıkay, Joseph G Gleeson, James R Lupski, Jean-Laurent Casanova, David J Pagliarini, Nurten A Akarsu, Sebastian Maurer-Stroh, Arda Cetinkaya, Aida Bertoli-Avella, Ajay S Mathuru, Lena Ho, Frederic A Bard, Bruno Reversade
AJHG, Volume 108, Issue 7, 1 July 2021, Pages 1301-1317. DOI: 10.1016/j.ajhg.2021.05.003
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NUS-CMU Joint Symposium 2021
23-24 September 2021
Organizing Chairs: Dr Derrick Ong, Dr Ling Shuo-Chien, Dr Tsai Shih-Yin, Dr Takaomi Sanda. Advisor: Prof Reshma Taneja
Organizing Committee Members: Ms Tan Shu Yi, Ms Koh Shu Wen, Mr Hong Jian Hui Cedric, Ms Koh Kang Sheing Phoebe

Asia Pacific Medical Education Conference (APMEC) 2022
January 2022
Conference website

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Contents: IT, Events & Publicity Team
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