2024

1. Tsai SY. Lost in translation: challenges of current pharmacotherapy for sarcopenia. Trends Mol Med. 2024 Jun 15:S1471-4914(24)00138-2. doi: 10.1016/j.molmed.2024.05.016.

2023

1. Dong H, and Tsai SY. Mitochondrial Properties in Skeletal Muscle Fiber. Cells 2023 Aug 30; 12(17):2183. doi: 10.3390/cells12172183.

2022

1. Ang ST, TAN KT, Hernando A, Yu D, Dong H, Adamson S, Crombie EM, Withers DJ, Huang H, Tsai SY. Muscle 4EBP1 activation modifies the structure and function of the neuromuscular junction in mice. Nat Commun 2022 Dec 17;13(1):7792. doi: 10.1038/s41467-022-35547-0.

2. Crombie EM, Kim S, Adamson S, Dong H, Lu TC, Wu Y, Wu Y, Levy Y, Stimple N, Lam WM, Hey HW, Withers DJ, Hsu AL, Bay BH, Ochala J, Tsai SY. Activation of eIF4E-binding-protein-1 rescues mTORC1-induced sarcopenia by expanding lysosomal degradation capacity. J Cachexia Sarcopenia Muscle.2022 Nov 17. doi: 10.1002/jcsm.13121.

3. Tan H, Lu G, Cho YL, Dong H, Wang L, Natalia A, Chan C, Kappei D, Taneja R, Ling SC, Shao H, Tsai SY, Ding WX, and Shen HM. 2022. A degradative to secretory autophagy switch mediates mitochondria clearance in the absence of the mATG8-conjugation machinery. Nat Commun 2022 Jun 28;13(1):3720. doi: 10.1038/s41467-022-31213-7.

4. Hey HWD, Lam WMR, Chan CX, Zhuo WH, Crombie EM, Tan TC, Chen WC, Cool S, and Tsai SY. Paraspinal myopathy-induced intervertebral disc degeneration and thoracolumbar kyphosis in TSC1mKO mice model-a preliminary study. Spine J. 2022 Mar;22(3):483-494. doi: 10.1016/j.spinee.2021.09.003.

2019

1. Tan KT, Ang STJ, Tsai SY. 2019. Sarcopenia: Tilting the Balance of Protein Homeostasis. Proteomics. doi: 10.1002/pmic.201800411

2017

1. Kent LN*, Bae S*, Tsai SY*, Tang X, Srivastava A, Koivisto C, Martin CK, Ridolfi E, Miller GC, Zorko SM, Plevris E, Hadjiyannis Y, Perez M, Nolan E, Kladney R, Westendorp B, de Bruin A, Fernandez S, Rosol TJ, Pohar KS, Pipas JM, Leone G. 2017. Dosage-dependent copy number gains in E2f1 and E2f3 drive hepatocellular carcinoma. J Clin Invest. 127(3):830-842. PMID: 28134624. *Equal Contributions.

2016

1. Tsai SY, Rodriguez AA, Dastidar SG, Del Greco E, Carr KL, Sitzmann JM, Academia EC, Viray CM, Martinez LL, Kaplowitz BS, Ashe TD, La Spada AR, Kennedy BK. 2016. Increased 4E-BP1 expression protects against diet-induced obesity and insulin resistance in male mice. Cell Report. 16(7):1903-14. PMD: 27498874.

2015

1. Tsai SY, Sitzmann JM, Dastidar SG, Rodriguez AA, Vu SL, McDonald CE, Academia EC, O'Leary MN, Ashe TD, La Spada AR, Kennedy BK. 2015. Muscle-specific 4E-BP1 signaling activation improves metabolic parameters during aging and obesity. J Clin Invest. 125(8):2952-64. PMID: 26121750.

2. Julian LM, Liu Y, Pakenham CA, Dugal-Tessier D, Ruzhynsky V, Bae S, Tsai SY, Leone G, Slack RS, Blais A. 2015. Tissue-specific targeting of cell fate regulatory genes by E2f factors. Cell Death Differ. 23(4):565-75. PMID: 25909886.

2010

1. McCormick MA, Tsai SY, Kennedy BK. 2010. TOR and Aging: A complex pathway for a complex process. Philos Trans R Soc Lond B Biol Sci. 366(1561), 17-27. PMID: 21115526.

2009

1. Chen HZ, Tsai SY, & Leone G. 2009. Emerging roles of E2Fs in cancer: an exit from cell cycle control. Nat. Rev. Cancer. 9(11), 785-79. PMID: 19851314.

2. Chong JL, Tsai SY, Sharma N, Opavsky R, Price R, Wu L, Fernandez SA, Leone G. 2009. E2f3a and E2f3b contribute to the control of cell proliferation and mouse development. Mol Cell Biol. 29(2), 414-424 PMID: 19015245.

2008

1. Tsai SY, Opavsky R, Sharma N, Wu L, Naidu S, Nolan E, Feria-Arias E, Timmers C, Opavska J, de Bruin A, Chong JL, Trikha P, Fernandez SA, Stromberg P, Rosol TJ, Leone G. 2008. Mouse development with a single E2F activator. Nature. 454, 1137-1141 PMID: 18594513.

2007

1. Opavsky R, Tsai SY, Guimond M, Arora A, Opavska J, Becknell B, Kaufmann M, Walton NA, Stephens JA, Fernandez SA, Muthusamy N, Felsher DW, Porcu P, Caligiuri MA, Leone G.2007. Specific tumor suppressor function for E2F2 in Myc-induced T cell lymphomagenesis. Proc. Natl Acad. Sci. USA 104, 15400-15405 PMID: 17881568.

2004

1. Hsu CL, Chen YS, Tsai SY, Tu PJ, Wang MJ, Lin JJ. 2004. Interaction of Saccharomyces Cdc13p with Pol1p, Imp4p, Sir4p and Zds2p is involved in telomere replication, telomere maintenance and cell growth control. Nucleic Acids Res. 32(2):511-521 PMID: 14742666.