Publications
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Full list of publication (PDF)
Updated as of Aug 2018
10 selected publications
Importance of TFEB acetylation in control of its
transcriptional activity and lysosomal function in response
to histone deacetylase inhibitors.
Zhang J, Wang J, Zhou Z, Park JE, Wang L, Wu S, Sun X, Lu L, Wang T, Lin Q, Sze SK, Huang D,
Shen HM .
Autophagy. 2018;14(6):1043-1059. doi: 10.1080/15548627.2018.1447290. Epub 2018 Jul 30. PMID: 30059277
PTEN-L is a novel protein phosphatase for
ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy.
Wang L, Cho YL, Tang Y, Wang J, Park JE, Wu Y, Wang C, Tong Y, Chawla R, Zhang J, Shi Y, Deng S, Lu
G, Wu Y,
Tan HW, Pawijit P, Lim GG, Chan HY, Zhang J, Fang L, Yu H, Liou YC, Karthik M, Bay BH, Lim KL, Sze SK,
Yap
CT,
Shen HM .
Cell Res. 2018 Aug;28(8):787-802. doi: 10.1038/s41422-018-0056-0. Epub 2018 Jun 22. Erratum in: Cell
Res. 2018
Jul 23;:. PMID: 29934616
Nonradioactive quantification of autophagic protein
degradation with L-azidohomoalanine labeling.
Wang J, Zhang J, Lee YM, Ng S, Shi Y, Hua ZC, Lin Q,
Shen HM .
Nat Protoc. 2017 Dec;12(2):279-288. doi: 10.1038/nprot.2016.160. Epub 2017 Jan 12. PMID: 28079880
Critical role of CAV1/caveolin-1 in cell stress
responses in human breast cancer cells via modulation of lysosomal
function and autophagy.
Shi Y, Tan SH, Ng S, Zhou J, Yang ND, Koo GB, McMahon KA, Parton RG, Hill MM, Del Pozo MA, Kim YS,
Shen HM .
Autophagy. 2015;11(5):769-84. doi: 10.1080/15548627.2015.1034411. PMID: 25945613
At the end of the autophagic road: an emerging
understanding of lysosomal functions in autophagy.
Shen HM , Mizushima N.
Trends Biochem Sci. 2014 Feb;39(2):61-71. doi: 10.1016/j.tibs.2013.12.001. Epub 2013 Dec 24. Review.
PMID:
24369758
Activation of lysosomal function in the course of
autophagy via mTORC1 suppression and autophagosome-lysosome
fusion.
Zhou J, Tan SH, Nicolas V, Bauvy C, Yang ND, Zhang J, Xue Y, Codogno P,
Shen HM .
Cell Res. 2013 Apr;23(4):508-23. doi: 10.1038/cr.2013.11. Epub 2013 Jan 22. PMID: 23337583
zVAD-induced necroptosis in L929 cells depends on
autocrine production of TNFα mediated by the PKC-MAPKs-AP-1
pathway.
Wu YT, Tan HL, Huang Q, Sun XJ, Zhu X,
Shen HM .
Cell Death Differ. 2011 Jan;18(1):26-37. doi: 10.1038/cdd.2010.72. Epub 2010 Jun 11. PMID: 20539307
Dual role of 3-methyladenine in modulation of
autophagy via different temporal patterns of inhibition on class
I and III phosphoinositide 3-kinase.
Wu YT, Tan HL, Shui G, Bauvy C, Huang Q, Wenk MR, Ong CN, Codogno P,
Shen HM .
J Biol Chem. 2010 Apr 2;285(14):10850-61. doi: 10.1074/jbc.M109.080796. Epub 2010 Feb 1. PMID:
20123989
Autophagy plays a protective role during
zVAD-induced necrotic cell death.
Wu YT, Tan HL, Huang Q, Kim YS, Pan N, Ong WY, Liu ZG, Ong CN,
Shen HM .
Autophagy. 2008 May;4(4):457-66. Epub 2008 Feb 1. PMID: 18253089
c-Jun N-terminal kinase mediates hydrogen
peroxide-induced cell death via sustained poly(ADP-ribose) polymerase-1
activation.
Zhang S, Lin Y, Kim YS, Hande MP, Liu ZG,
Shen HM .
Cell Death Differ. 2007 May;14(5):1001-10. Epub 2007 Jan 12. PMID: 17218956
Book Edited
Necrotic cell death, Editors:
Shen HM and Vandenabeele P, Humana Press, 2014