Publications

Updated as of Aug 2018

10 selected publications

  1. Importance of TFEB acetylation in control of its transcriptional activity and lysosomal function in response to histone deacetylase inhibitors.
    Zhang J, Wang J, Zhou Z, Park JE, Wang L, Wu S, Sun X, Lu L, Wang T, Lin Q, Sze SK, Huang D, Shen HM.
    Autophagy. 2018;14(6):1043-1059. doi: 10.1080/15548627.2018.1447290. Epub 2018 Jul 30. PMID: 30059277
  2. PTEN-L is a novel protein phosphatase for ubiquitin dephosphorylation to inhibit PINK1-Parkin-mediated mitophagy.
    Wang L, Cho YL, Tang Y, Wang J, Park JE, Wu Y, Wang C, Tong Y, Chawla R, Zhang J, Shi Y, Deng S, Lu G, Wu Y, Tan HW, Pawijit P, Lim GG, Chan HY, Zhang J, Fang L, Yu H, Liou YC, Karthik M, Bay BH, Lim KL, Sze SK, Yap CT, Shen HM.
    Cell Res. 2018 Aug;28(8):787-802. doi: 10.1038/s41422-018-0056-0. Epub 2018 Jun 22. Erratum in: Cell Res. 2018 Jul 23;:. PMID: 29934616
  3. Nonradioactive quantification of autophagic protein degradation with L-azidohomoalanine labeling.
    Wang J, Zhang J, Lee YM, Ng S, Shi Y, Hua ZC, Lin Q, Shen HM.
    Nat Protoc. 2017 Dec;12(2):279-288. doi: 10.1038/nprot.2016.160. Epub 2017 Jan 12. PMID: 28079880
  4. Critical role of CAV1/caveolin-1 in cell stress responses in human breast cancer cells via modulation of lysosomal function and autophagy.
    Shi Y, Tan SH, Ng S, Zhou J, Yang ND, Koo GB, McMahon KA, Parton RG, Hill MM, Del Pozo MA, Kim YS, Shen HM.
    Autophagy. 2015;11(5):769-84. doi: 10.1080/15548627.2015.1034411. PMID: 25945613
  5. At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy.
    Shen HM, Mizushima N.
    Trends Biochem Sci. 2014 Feb;39(2):61-71. doi: 10.1016/j.tibs.2013.12.001. Epub 2013 Dec 24. Review. PMID: 24369758
  6. Activation of lysosomal function in the course of autophagy via mTORC1 suppression and autophagosome-lysosome fusion.
    Zhou J, Tan SH, Nicolas V, Bauvy C, Yang ND, Zhang J, Xue Y, Codogno P, Shen HM.
    Cell Res. 2013 Apr;23(4):508-23. doi: 10.1038/cr.2013.11. Epub 2013 Jan 22. PMID: 23337583
  7. zVAD-induced necroptosis in L929 cells depends on autocrine production of TNFα mediated by the PKC-MAPKs-AP-1 pathway.
    Wu YT, Tan HL, Huang Q, Sun XJ, Zhu X, Shen HM.
    Cell Death Differ. 2011 Jan;18(1):26-37. doi: 10.1038/cdd.2010.72. Epub 2010 Jun 11. PMID: 20539307
  8. Dual role of 3-methyladenine in modulation of autophagy via different temporal patterns of inhibition on class I and III phosphoinositide 3-kinase.
    Wu YT, Tan HL, Shui G, Bauvy C, Huang Q, Wenk MR, Ong CN, Codogno P, Shen HM.
    J Biol Chem. 2010 Apr 2;285(14):10850-61. doi: 10.1074/jbc.M109.080796. Epub 2010 Feb 1. PMID: 20123989
  9. Autophagy plays a protective role during zVAD-induced necrotic cell death.
    Wu YT, Tan HL, Huang Q, Kim YS, Pan N, Ong WY, Liu ZG, Ong CN, Shen HM.
    Autophagy. 2008 May;4(4):457-66. Epub 2008 Feb 1. PMID: 18253089
  10. c-Jun N-terminal kinase mediates hydrogen peroxide-induced cell death via sustained poly(ADP-ribose) polymerase-1 activation.
    Zhang S, Lin Y, Kim YS, Hande MP, Liu ZG, Shen HM.
    Cell Death Differ. 2007 May;14(5):1001-10. Epub 2007 Jan 12. PMID: 17218956

Book Edited

  1. Necrotic cell death, Editors: Shen HM and Vandenabeele P, Humana Press, 2014