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For full list of publications on pubmed
https://www.ncbi.nlm.nih.gov/pubmed/?term=hande+mp+OR+hande+p+OR+prakash+hande


2021

  • Zeegers D, Hande V, Low GKM, Sethu S, Venkatesan S, Jayapal M, Martinez-Lopez W, Hande MP† 2021 Cyto-genotoxic effects of sodium arsenite in human cells – A multiparametric analysis. (In preparation).
  • Sameni S, Viswanathan R, Hande MP† 2021 Telomerase inhibition by MST-312 sensitises breast cancer cells to anti-cancer properties of Plumbagin (in preparation).
  • Ng GY-Q, Sheng DPLK, Kang SW, Fann DY-W, Kim J, Alli-Shaik A, Park J, Lee J, Kim E, Han JW, Karamyan V, Okun E, Dheen T, Hande MP, Vemuganti R, Mallilankaraman K, Lim LHK, Kennedy BK, Drummond G, Sobey CG, Gunaratne J, Mattson MP, Foo RS-Y, Jo D-G, Arumugam TV 2021 Integrative epigenomic and transcriptomic analyses reveal metabolic switch by intermittent fasting in brain. (Submitted).
  • Ng, GYQ, Tan KH, Ong HM, Wong BWX, Hande V, Fann DYW, Arumugam TV, Hande MP† 2021 Dietary intervention and telomere dynamics (under submission).
  • Nugroho H, Surniyantoro E, Darlina D, Rahardjo T, Rahajeng N, Kisnanto T, Nurhayati S, Lusiyanti Y, Syaifudin M, Hande MP 2021 Assessment of hOGG1 genetic polymorphism (rs1052133) and DNA damage in radiation exposed workers (Submitted).
  • Low GKM, Ting APL, Fok EDZ, Gopalakrishnan K, Zeegers, D, Khaw AK, Jayapal M, Martinez-Lopez W, Hande MP† 2021 Role of xeroderma pigmentosum D (XPD) protein in genome maintenance in human cells under oxidative stress Mutation Research – Genetic Toxicology and Environmental Toxicology (Submitted).
  • Chakraborty A, Pal I, Roy S, Koh SW, Hande MP, Banerjee B 2020 A novel de-novo balanced chromosomal translocation 19:22 along with 13ps+ n an azoospermic male: a case report. Journal of Reproduction & Infertility Vol 22 (2): 133 – 137.
  • Gregoire E, Barquinero JF, Gruel G, Benadjaoud M, Ainsbury E, Beinke C, Balajee A, , Beukes P, Blakely W, Dominguez I, Duy PN, Flegal FN, Gil OM, Güçlü I, Guogyte K, Hadjidekova V, Hadjidekova SP, Hande P, Jang S, Lumniczky K, Martinez JG, Meschini R, Milic M, Montoro A, Moreno M, Oestreicher U, Pajic J, Ricoul M, Sabatier L, Sebastia N, Sommer S, Szkarlat Z, Testa A, Terzoudi G, Valente M, Venkatachalam P, Vral A, Wilkins RC, Wojcik A, Zafiropoulos D, Kulka U. 2021 RENEB Inter-Laboratory Comparison 2017: limits and pitfalls of ILCs. International Journal of Radiation Biology 1-18 (DOI: 10.1080/09553002.2021.1928782)
  • Hande V, Teo KYS, Wong JSM, Srikath P, Sethu S, Martinez-Lopez W, Hande MP† 2021 Investigations on the new mechanism of action for acetaldehyde-induced clastogenic effects in human lung fibroblasts. Mutation Research – Genetic Toxicology and Environmental Mutagenesis 861 -862: DOI: 10.1016/j.mrgentox.2020.503303

2020

  • Ong YB, Thambiayah U, Koh PKS, Nassir NM, Wong HL, Hande MP† 2020 Use of digital platform to encourage good laboratory practices during departmental safety inspections. Journal of Environment and Safety, 11(2): 7 – 10.
  • Luo Y, Viswanathan R, Hande MP, Loh AHP, Cheow LF 2020 Massively parallel single molecule telomere length measurement with digital real-time PCR. Science Advances Vol. 6, no. 34, eabb7944 DOI: 10.1126/sciadv.abb7944
  • Kandilya D, Shyamasundar, S, Singh DK, Banik A, Hande MP, Stunkel W, Chong YS, Dheen ST 2020 High glucose alters the DNA methylation pattern of neurodevelopment associated genes in human neural progenitor cells. Scientific Reports 10(1): 15676. doi: 10.1038/s41598-020-72485-7
  • Vinnikov V, Hande P, Wilkins R, Wojcik A, Zubizarreta E, Belyakov O 2020 Prediction of the acute or late radiation toxicity effects in radiotherapy patients using ex vico induced biodosimetric markers: A review. Journal of Personalized Medicine. 10(4), 285

2019

  • Ng GY-Q, Kang S-W, Kim J, Shaik AA, Baik S-H, Jo D-G, Hande MP, Sobey CG, Gunaratne J, , Fann DY- W, Arumugam TV. 2019 Genome-wide transcriptome analysis reveals intermittent fasting-induced metabolic rewriting in the liver. Dose Response 17(3):1559325819876780. doi: 10.1177/1559325819876780.
  • Roy S, Roy S, Kar M, Chakraborty A, Kumar A, Delogu F, Asthana S, Hande MP, Banerjee B 2019 Combined effect of cisplatin and XAV939 leads to increase in cytotoxicity and abrogates cancer stem-like cells mediated chemo resistance in head and neck squamous cell carcinoma. Mutation Research vol. 846 ( October 2019) (doi: 10.1016/j.mrgentox.2019.503084.
  • Kandilya D, Maskomani S, Shyamasundar S, Tambyah PA, Chan SY, Ching RHL, Hande MP, Mallilankaraman K, Chu JJH, Dheen ST 2019 ZIKV alters DNA methylation status of genes involved in Hippo signaling pathway in human neural progenitor cells. Epigenomics 11(10): 1143 – 1161.
  • Chakraborty A, Panda SK, Mohakud NK, Roy D, Padhi S, Koh SW, Hande MP, Banerjee B 2019 A child with partial trisomy 4 (q46 – q terminal) resulting from paternally inherited translocation (4:18) associated with multiple congenital anomalies and death. A case report. Genome Integrity Vol 10, 1.

2018

  • Gopalakrishnan K, Venkatesan S, Low E, Hande MP† 2018 Effects of rapamycin on the mechanistic target of rapamycin (mTOR) pathway and telomerase in breast cancer cells. Mutation Research – Genetic Toxicology and Environmental Mutagenesis 836 (Part B), 103 – 113.
  • George, A, Venkatesan S, Ashok N, Saraswathy R, Hande MP† 2018 Assessment of genomic instability and proliferation index in the cultured lymphocytes of cancer prone syndromes. Mutation Research – Genetic Toxicology and Environmental Mutagenesis, 836 (Part A): 98 -103.
  • Roy S, Roy S, Rana A, Akhter Y, Hande MP, Banerjee B 2018 The role of p38 and p53 mutated state in co-relationship with genotoxic stress and telomere regulated DNA damage response. Mutation Research – Genetic Toxicology and Environmental Mutagenesis 836 (Part A): 89 - 97.
  • Balajee AS† and Hande MP† 2018 History and Evolution of cytogenetic techniques: Current and Future applications in basic and clinical research. Mutation Research – Genetic Toxicology and Environmental Mutagenesis, 836 (Part A): 3 – 12.
  • Balajee AS, Palitti F, Surralles J, Hande MP† 2018 Editorial and Obituary: Professor Adayapalam T Natarajan. Mutation Research – Genetic Toxicology and Environmental Mutagenesis. 836 (Part A): 1 – 2.

2017

  • Lim HK, Gurung RL, Hande MP† 2017 DNA-dependent protein kinase modulates the anti-cancer properties of silver nanoparticles in human cancer cells. Mutation Research – Genetic Toxicology and Environmental Mutagenesis, 824: 32 – 41.
  • Venkatesan S, Khaw AK, Hande MP† 2017 Telomere Biology – Insights into an Intriguing Phenomenon. Cells 6(2): pii: E15. doi: 10.3390/cells6020015.
  • Lee SP, Hande P, Yeo GS, Tan EC 2017 Correlation of cord blood telomere length with birth weight. BMC Research Notes 10(1): 469. doi: 10.1186/s13104-017-2791-6.
  • Ng CT, Yong LQ, Hande MP, Ong CN, Yu L, Bay BH, Baeg GH 2017 Zinc oxide nanoparticles exhibit cytotoxicity and genotoxicity through oxidative stress responses in human lung fibroblasts and Drosophila melanogaster. International Journal of Nanomedicine 2017:12 1621–1637.
  • Zeegers D, Venkatesan S, Koh SW, Srivastava P, Sundaram N, Sethu S, Banerjee B, Jayapal M, Belyakov O, Baskar R, Balajee AS, Hande MP† Biomarkers of ionising radiation exposure: A multiparametric approach. Genome Integrity, 8: 6.
  • Hande MP† 2017 Book Review: Toxicogenomics in Predictive Carcinogenicity. Frontiers in Genetics 8, 11.
  • Oestreicher U, Samaga D, Ainsbury E, Antunes AC, Baeyens A, Barrios L, Beinke C, Beukes P, Blakely WF, Cucu A, De Amicis A, Depuydt J, De Sanctis S, Di Giorgio M, Dobos K, Dominguez I, Duy PN, Espinoza ME, Flegal FN, Figel M, Garcia O, Monteiro Gil O, Gregoire E, Guerrero-Carbajal C, Güçlü İ, Hadjidekova V, Hande P, Kulka U, Lemon J, Lindholm C, Lista F, Lumniczky K, Martinez-Lopez W, Maznyk N, Meschini R, M'kacher R, Montoro A, Moquet J, Moreno M, Noditi M, Pajic J, Radl A, Ricoul M, Romm H, Roy L, Sabatier L, Sebastià N, Slabbert J, Sommer S, Stuck Oliveira M, Subramanian U, Suto Y, Que T, Testa A, Terzoudi G, Vral A, Wilkins R, Yanti L, Zafiropoulos D, Wojcik A 2017 RENEB intercomparisons applying the conventional dicentric chromosome assay (DCA). International Journal of Radiation Biology 93(1):20-29.

2016

  • Kalthur G, Salian SR, Nair R, Mathew J, Adiga SK, Kalthur SG, Zeegers D, Hande MP 2016 Distribution pattern of cytoplasmic organelles, spindle integrity, oxidative stress, octamer-binding transcription factor 4 (Oct 4) expression and developmental potential of oocytes following multiple superovulation. Reproduction, Fertility and Development 28(12): 2027 – 2038. doi: 10.1071/RD15184
  • Hande MP† , Sharan RN, Belyakov O 2016 Strengthening biological dosimetry in IAEA-member states. Genome Integrity, 7:1.
  • El Ghamrasni, S, Cardoso R, Li L, Guturi KK, Bjerregaard V, Liu Y, Venkatesan S, Hande MP, Henderson JT, Sanchez O, Hickson ID, Hakem A, Hakem R 2016 Rad54 and Mus81 cooperation mediates the repair of DNA double strand breaks and restrains genomic instability and chromosome missegregation. Oncogene 35(37):4836-4845
  • Sameni S, Hande MP† 2016 Plumbagin treatment triggers DNA damage response, telomere dysfunction and genome instability of human breast cancer cells, Biomedicine and Pharmacotherapy 82:256-268
  • Somyajit K, Banik B, Saxena S, Hande MP, Chakravarty AR, Nagaraju G 2016 Trans-dichlorooxovandium (IV) complex as a potent photoinducible DNA interstrand cross-linker for targeted cancer therapy. Carcinogenesis 37(2): 145 – 156.

2015

  • Venkatesan S, Natarajan AT, Hande MP† 2015 Chromosomal instability – mechanisms and consequences. Mutation Research – Genetic Toxicology and Environmental Mutagenesis 793: 176 – 184.
  • Khaw AK, Sameni S, Kalthur G, Hande MP† 2015 Plumbagin alters telomere dynamics, induces DNA damage and cell death in human brain tumour cells. Mutation Research – Genetic Toxicology and Environmental Mutagenesis 793: 86 – 95.
  • Vinoth KJ, Manikanadan J, Sethu S, Balakrishnan L, Heng A, Lu K, Poonepalli A, Hande MP† , Cao T† 2015 Differential resistance of human embryonic stem cells and somatic cell types to hydrogen peroxide-induced genotoxicity may be dependent on innate basal intracellular ROS levels. Folia histochemical et Cytobiologica 53(2): 169 – 174.
  • El Ghamrasni S, Cardoso R, Halaby M-J, Zeegers D, Harding S, Kumareswaran R, Yavorska T, Chami N, Jurisicova A, Sanchez, Hande MP, Bristow R, Hakem A, Hakem R 2015 Cooperation of Blm and Mus81 in Development, Fertility, Genomic Integrity and Cancer Suppression. Oncogene 34 (14): 1780 -1789.
  • Padhi, S, Saha A, Kar M, Ghosh C, Adhya A, Baisakh M, Mohapatra N, Venkatesan S, Hande MP, Banerjee B 2015 Clinico-pathological correlation of β-catenin and telomere dysfunction in head and neck squamous cell carcinoma patients. Journal of Cancer 6(2): 192 – 202.

2014

  • Bull CF, Mayrhofer G, O’Callaghan NJ, Low GKM, Zeegers D, Hande MP, Au AY, Pickett HA, Fenech MF 2014 Folate deficiency causes rapid telomere length changes, DNA hypomethylation, chromosome breakage and genomic instability in human WIL2-NS cells. Cancer Prevention Research 7 (1): 128 – 138.
  • Vinoth KJ, Manikandan J, Sethu S, Balakrishnan L, Heng A, Lu K, Hande MP†, Cao T† 2014 Evaluation of Human Embryonic Stem Cells and their Differentiated Fibroblastic Progenies as Cellular Models for In Vitro Genotoxicity Screening. Journal of Biotechnology 184:154 -168.
  • Gurung RL, Lim HK, Venkatesan S, Lee PS, Hande MP 2014 Targeting DNA-PKcs and telomerase in brain tumour cells. Molecular Cancer 13(1): 232 doi: 10.1186/1476-4598-13-232.
  • Gurung RL, Lim SN, Low GKM, Hande MP, 2014 MST-312 alters telomere dynamics and gene expression profiles and sensitises human breast cancer cells to PARP-1 inhibition. Journal of Nutrigenetics and Nutrigenomics 7: 283 – 298.

2013

  • Lim SN, Yahya Z, Zeegers D, Moe T, Kyaw EEP, Yeo GSH, Hande MP, Tan EC 2013 Distribution of telomere length in the cord blood of Chinese newborns. British Journal of Medicine and Medical Research .3(4):1004 -1014.
  • Ng C-T, Li JJ, Gurung RL, Hande MP, Ong C-N, Bay BH, Yung LYL 2013 Toxicological profile of small airway epithelial cells exposed to gold nanoparticles. Experimental Biology and Medicine . 238(12): 1355 - 1361.
  • Pavagadhi S, Betha R, Venkatesan S, Balasubramanian R, Hande MP 2013 Physicochemical and toxicological characteristics of urban aerosols during a recent Indonesian biomass burning episode. Environmental Science and Pollution Research . 2013 Apr;20(4): 2569 – 2578.
  • Banerjee B, Hande MP 2013 Age-independent telomere shortening and ion-channel defects in SCD. Nature Reviews Cardiology . 2013 Jun;10(6):362.
  • Halaby MJ, Hakem A, Li L, El Ghamrasni S, Venkatesan S, Hande PM, Sanchez O, Hakem R 2013 Synergistic interaction of Rnf8 and p53 in the protection against genomic instability and tumorigenesis. PLoS Genetics . 2013 Jan 31;9(1):e1003259
  • Khaw AK, Hande MP, Kalthur G, Hande MP 2013 Curcumin inhibits telomerase and induces telomere shortening and apoptosis in brain tumour cells. Journal of Cellular Biochemistry . 2013 Jun; 114(6):1257–1270.

2012

  • Yong JW, Yeo X, Khan MM, Lee MB, Hande MP 2012 Stable expression of promyelocytic leukaemia (PML) protein in telomerase positive MCF7 cells results in alternative lengthening of telomeres phenotype. Genome Integr. 2012 Aug 27;3(1):5.
  • Khaw AK, Yong JW, Kalthur G, Hande MP 2012 Genistein induces growth arrest and suppresses telomerase activity in brain tumor cells. Genes Chromosomes Cancer. 2012 Oct;51(10):961-74.
  • Lim HK, Asharani PV, Hande MP 2012 Enhanced genotoxicity of silver nanoparticles in DNA repair deficient Mammalian cells. Front Genet. 2012;3:104.
  • Suram A, Kaplunov J, Patel PL, Ruan H, Cerutti A, Boccardi V, Fumagalli M, Di Micco R, Mirani N, Gurung RL, Hande MP, d'Adda di Fagagna F, Herbig U 2012 Oncogene-induced telomere dysfunction enforces cellular senescence in human cancer precursor lesions. EMBO J. 2012 May 8;31(13):2839-51.
  • Bull CF, Mayrhofer G, Zeegers D, Mun GL, Hande MP, Fenech MF 2012 Folate deficiency is associated with the formation of complex nuclear anomalies in the cytokinesis-block micronucleus cytome assay. Environ Mol Mutagen. 2012 May;53(4):311-23.
  • Asharani P, Sethu S, Lim HK, Balaji G, Valiyaveettil S, Hande MP 2012 Differential regulation of intracellular factors mediating cell cycle, DNA repair and inflammation following exposure to silver nanoparticles in human cells. Genome Integr. 2012 Feb 10;10;3(1):2.

2011

  • Pavagadhi S, Gong Z, Hande MP, Dionysiou DD, de la Cruz AA, Balasubramanian R 2011 Biochemical response of diverse organs in adult Danio rerio (zebrafish) exposed to sub-lethal concentrations of microcystin-LR and microcystin-RR: A balneation study. Aquat Toxicol. 2011 Nov 26;109C:1-10.
  • Manikandan J, Kothandaraman N, Hande MP, Pushparaj PN 2011 Deciphering the structure and function of FcεRI/mast cell axis in the regulation of allergy and anaphylaxis: a functional genomics paradigm. Cell Mol Life Sci. 2011 Dec 7.
  • El Ghamrasni S, Pamidi A, Halaby MJ, Bohgaki M, Cardoso R, Li L, Venkatesan S, Sethu S, Hirao A, Mak TW, Hande MP, Hakem A, Hakem R 2011 Inactivation of chk2 and mus81 leads to impaired lymphocytes development, reduced genomic instability, and suppression of cancer. PLoS Genet. 2011 May;7(5):e1001385.
  • Bohgaki T, Bohgaki M, Cardoso R, Panier S, Zeegers D, Li L, Stewart GS, Sanchez O, Hande MP, Durocher D, Hakem A, Hakem R 2011 Genomic instability, defective spermatogenesis, immunodeficiency, and cancer in a mouse model of the RIDDLE syndrome. PLoS Genet. 2011 Apr;7(4):e1001381.
  • Li JJ, Lo SL, Ng CT, Gurung RL, Hartono D, Hande MP, Ong CN, Bay BH, Yung LY 2011 Genomic instability of gold nanoparticle treated human lung fibroblast cells. Biomaterials. 2011 Aug;32(23):5515-23.
  • Teow Y, Asharani PV, Hande MP, Valiyaveettil S 2011 Health impact and safety of engineered nanomaterials. Chem Commun (Camb). 2011 Jul 7;47(25):7025-38.