Alan

NUS Centre for Cancer Research Newsletter

 

A/P Gautam Sethi’s research work, Berberine inhibits breast carcinoma proliferation and metastasis under hypoxic microenvironment involving gut microbiota and endogenous metabolites, is highlighted in “Research highlights of 2023” of the N2CR INSIGHTS Issue 9, a quarterly newsletter of NUS Centre for Cancer Research Newsletter.

Read more: https://medicine.nus.edu.sg/trp/n2cr/wp-content/uploads/sites/8/2024/01/N2CR-INSIGHTS-Issue-9-Oct-Dec-2023-4.pdf

NUS Centre for Cancer Research Newsletter Read More »

Let’s mark World Alzheimer’s Day 2023 by recognising the extraordinary dedication of A/P Christopher Chen

Let’s mark World Alzheimer’s Day 2023, (every 21 Sep.) by recognising the extraordinary dedication of A/P Christopher Chen. His hard work has led to an FDA-approved Alzheimer’s drug, Lecanemab, offering a beacon of hope to millions.

World Alzheimer’s Day 2023 – NUS Yong Loo Lin School of Medicine Facebook: https://www.facebook.com/reel/619306613734798

Let’s mark World Alzheimer’s Day 2023 by recognising the extraordinary dedication of A/P Christopher Chen Read More »

NUS Medicine and Department of Pharmacology Achieve Top Rankings in Asia

The National University of Singapore (NUS) continues to make its mark in higher education, securing leading positions in the latest QS World University Rankings by subject. NUS Medicine has been ranked #20 in the world and #1 in Asia, while NUS Pharmacy & Pharmacology is tied for #10 in the world and also holds the #1 spot in Asia

The rankings highlight NUS’s commitment to providing world-class education and research in the fields of medicine and pharmacology. With a strong focus on innovation and interdisciplinary collaboration, NUS has been recognized for its outstanding performance in both fields. The rankings emphasize the growing influence of the NUS Medicine Department of Pharmacology on the global stage.

These achievements reflect the dedication of the NUS Medicine Department of Pharmacology’s faculty, staff, students, and researchers in pushing the boundaries of knowledge, education, and innovation. As a leading Department of Pharmacology in Asia, the NUS Medicine Department of Pharmacology remains committed to nurturing talent and contributing to the betterment of the region and the world.

For more information on the rankings, visit the Top Universities website and read the full article from The Straits Times (More Details) and see the QS World University Rankings for Pharmacy & Pharmacology 2023 (QS Rankings) via the links below.

NUS Medicine and Department of Pharmacology Achieve Top Rankings in Asia Read More »

Singapore scientists examine whether mushroom compound can help prevent, delay mental decline

Led by Prof Barry Halliwell from NUS Medicine Department of Biochemistry, and A/Prof Christopher Chen and Dr Mitchell Lai (both NUS Pharmacology) from the Memory, Ageing and Cognition Centre at NUHS, a group of scientists has restarted a clinical trial to look at whether supplementing one’s diet with ergothioneine – a compound found mainly in mushrooms – can help prevent or delay cognitive impairment and dementia, after they found that low levels of ergothioneine in the blood correlate with an increased risk of developing cognitive issues.

Singapore scientists examine whether mushroom compound can help prevent, delay mental decline Read More »

AI platform that suggests drug cocktail for patients with relapsed lymphoma to undergo clinical trial soon

In the near future, patients with relapsed lymphoma can likely enrol in a formal clinical trial that will personalise the most effective cocktail of drugs to treat their disease based on calculations done by an artificial intelligence (AI) platform. Led by Dr Anand Jeyasekharan and A/Prof Edward Chow (Department of Pharmacology) from the NUS Centre for Cancer Research (N2CR) and Cancer Science Institute of Singapore, a study on 17 patients who had suffered multiple lymphoma relapses saw significant improvement in eight of them after they took a cocktail of medication recommended by the platform. Of these eight patients, five had their cancer completely eradicated.

AI platform that suggests drug cocktail for patients with relapsed lymphoma to undergo clinical trial soon Read More »

Experimental Alzheimer’s drug found to slow progression of disease

Patients with Alzheimer’s disease – the most common cause of dementia – may soon get a new drug that can slow progression of the disease, a recent study has found.

Speaking to media on Tuesday, visiting consultant in the Department of Psychological Medicine at the National University Hospital (NUH) Christopher Chen (Associate Professor at Department of Pharmacology, NUS) said disease progression for patients who were given the drug known as lecanemab was found to be at least six months behind those who received a placebo after 18 months of treatment.

Experimental Alzheimer’s drug found to slow progression of disease Read More »

The new X-ray/visible microscopy MAXWELL technique for fast three-dimensional nanoimaging with isotropic resolution

Abstract

Microscopy by Achromatic X-rays With Emission of Laminar Light (MAXWELL) is a new X-ray/visible technique with attractive characteristics including isotropic resolution in all directions, large-volume imaging and high throughput. An ultrathin, laminar X-ray beam produced by a Wolter type I mirror irradiates the sample stimulating the emission of visible light by scintillating nanoparticles, captured by an optical system. Three-dimensional (3D) images are obtained by scanning the specimen with respect to the laminar beam. We implemented and tested the technique with a high-brightness undulator at SPring-8, demonstrating its validity for a variety of specimens. This work was performed under the Synchrotrons for Neuroscience-an Asia-Pacific Strategic Enterprise (SYNAPSE) collaboration.

The new X-ray/visible microscopy MAXWELL technique for fast three-dimensional nanoimaging with isotropic resolution Read More »