Research Projects
68GA-FAPI-46 PET /CT of Peritoneal Metastases in Patients with Gastric Cancer
PI – Asst Prof Zhang Jingjing
Albumin based nanovaccine to potentiate cancer immunotherapy
PI - Asst Prof Ni Qianqian
Albumin binder modification of cancer therapeutics
PI – Prof Chen Xiaoyuan
An improved lipid nanoparticle technology for folded messenger RNA delivery and gene editing
PI - Asst Prof Ni Qianqian
An oral prebiotic protected full-API Nanodrug (FAND) for precise manipulation of gut microbiota to amplify immune responses in colorectal cancer
PI – Prof Chen Xiaoyuan
Controlled Green Synthesis of Novel Radioactive Microspheres and Their Antitumor Study By Transcatheter Retrial Radiotherapy Embolization
PI – Asst Prof Zhang Jingjing
Coordinated mRNA-mn2+ nanovaccine for sting-mediated cancer immunotherapy
PI - Asst Prof Ni Qianqian
Design of nucleic acid immune agonist delivery platform technology to elicit potent and safe anti-tumor immunity
PI - Asst Prof Ni Qianqian
Design of polymer-modified lipid nanoparticle systems for lymph node targeted delivery to enhance cancer immunotherapy
PI – Dr Zhang Miao
Development of bladder cancer mRNA vaccine targeting MAGE family antigens
PI – Prof Chen Xiaoyuan
Development of individualized cancer vaccines
PI – Prof Chen Xiaoyuan
FAP Theranostics - Cancer-Associated Fibroblasts (CAFS)-Targeted Imaging And Therapy And Combination With Immunotherapy or Chemotherapy (Including Also Other Radioligands)
PI – Asst Prof Zhang Jingjing
Glymphatic Neuroimaging: Linking Alzheimers Disease, Inflammation and Aging
PI – Asst Prof Choi Yoon Seong
In SITU therapeutic nanovaccine for personalized cancer immunotherapy
PI – Prof Chen Xiaoyuan
Lipid Nanoparticle Platform Technology For Targeted MRNA Delivery
PI – Asst Prof Ni Qianqian
Mechanism-based Design of Programmable Nanoparticle Delivery Vehicles for RNA Therapeutics: Controlling Endosomal Escape
PI – Prof Chen Xiaoyuan
Nanomedicine Translational Research Programme
PI – Prof Chen Xiaoyuan
Neuroimaging Markers For Aging, Cognition and Neurodegenerative Diseases
PI – Asst Prof Choi Yoon Seong
Novel Dimeric Long-Acting Fibroblast Activation Protein Inhibitors for Radioligand Imaging and Therapy of Cancer
PI – Asst Prof Zhang Jingjing
Novel Gastrin-Releasing Peptide Receptor (GRPR) And Integrin avb3 Dual-Targeting Probes for Radiotheranostics of Prostate Cancer
PI – Asst Prof Zhang Jingjing
Peripheral Venous Access for Safer Liver Biopsy System
PI – Asst Prof Kamarjit Singh
Phase 1, Open-Label Study of the Safety and Dosimetry of a 4-Dose Regimen of Escalating Doses of 177LU-LNC1004 Injection In Adult Patients With Advanced Fibroblast Activation Protein (FAP)-Positive sol
PI – Prof Khong Pek Lan
Polymeric nanogel delivering mRNA to lesional macrophages for synergistic anti-oxidative and anti-inflammatory treatment of atherosclerosis
PI – Prof Chen Xiaoyuan
Precision Brain Connectivity Profiling of Executive Dysfunction for Future therapeutic Strategy Using Network-Targeted Neurostimulation
PI – Asst Prof Tan Ai Peng
Precision Brain Connectivity Profiling of Learning Difficulties for Future Therapeutic Strategy Using Network-Targeted Neurostimulation (BRACO-LD)
PI – Asst Prof Tan Ai Peng
Process development and clinical trial authorization of 177LU DOTA-EB-FAPI (LNC-1004)
PI – Prof Chen Xiaoyuan
Process development and clinical trial authorization of 177LU DOTA-EB-THRETIDE (LNC-1003)
PI – Prof Chen Xiaoyuan
Quantitative NIR-IIB lifetime imaging of glutathione in metastatic melanoma
PI – Prof Chen Xiaoyuan
RADIOCMC dossier preparation, production and PET (Positron Emission Tomography)/ CT (Computerized Tomography) Scan [68Ga-FAPI46]
PI – Prof Chen Xiaoyuan
Radiolabeled Albumin-Binding Somatostatin Analog 177LU-DOTA-EB-Tate for Peptidereceptor Radionuclide Therapy of Recurrent or Metastatic Nasopharyngeal Carcinoma
PI – Asst Prof Zhang Jingjing
Radionuclide Theranostics
PI – Asst Prof Zhang Jingjing
T cell targeted dendrimer nanoparticlesmediate in-vivo mRNA delivery for humancart engineering
PI – Asst Prof Ni Qianqian
Translational Nanomedicine and Theranostics
PI – Prof Chen Xiaoyuan