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Developing a system for the use of natural language for the robust measurement of health-related quality of life, self-reported health and related patient reported outcome measures
| Funder: | National University of Singapore |
|---|---|
| Duration: | 2024 - 2026 |
| Lead Investigator: | Jose M Valderas |
| Contributors | Ellie Choi, Arivazhagan Karunakan |
Patient-reported outcome measures (PROMs) are essential tools for capturing patients’ perceptions of their health status. However, these questionnaires can be lengthy and cumbersome, as multiple assessments are required to evaluate various domains of a patient’s well-being.
The aim of this study is to develop a prediction model that uses free-text data to predict scores across multiple existing validated questionnaires. A representative sample of the Singapore population will be recruited, and free-text responses will be analyzed using machine learning techniques and mapped to their corresponding questionnaire scores.
Patient-reported outcomes, experience, and cost-effectiveness of chronic disease management in Singapore: comparing with OECD countries and providing a baseline for Healthier SG
| Funder: | National University Health System |
|---|---|
| Duration: | 2023 - 2026 |
| Lead Investigator: | Luo Nan (SSHSPH) |
| Contributors | Jose M Valderas, Loraine Seng |
A cross-sectional household survey on individuals aged 45 years old and above with at least one chronic condition has been conducted. The outcomes and experiences of local patients with chronic diseases are evaluated.
We will also examine: (i) the patterns and descriptive epidemiology of multimorbidity, (ii) the relation between multimorbidity and Patient-Reported Experience Measures (PREMs)/ Patient-Reported Outcome Measures (PROMs) along sociodemographic strata and care model, (iii) the relation between multimorbidity and health services utilization by care model, and (iv) the identification of high-risk patients with multimorbidity.
Database of validated PROMs instruments in Singapore
| Funder: | National University of Singapore |
|---|---|
| Duration: | 2024 - 2026 |
| Lead Investigator: | Jenny Sumner |
| Contributors | Jose M Valderas, Neo Sin Hui |
Patient-reported outcome measures (PROMs) are essential tools in patient-centred care, enabling the measurement of symptoms, function, quality of life, and well-being from the patient’s perspective. PROMs developed in one cultural or linguistic context may not directly translate to another due to variations in interpretation, health beliefs, and language. Contextual validation is therefore critical to ensure measurement accuracy and relevance. In this study, we aim to identify what PROMs instruments have been validated in Singapore and to what extent. By systematically collecting and reporting these data, we can inform the implementation and eventual further development of patient-centred measures in Singapore.
Development and Testing of a Self-Administered Digital Psychological Toolkit to reducing Symptom burden and Morbidity in Dermatology Patients: a Multicentre Randomised Controlled Trial
| Funder: | National Medical Research Council |
|---|---|
| Duration: | 2024 - 2028 |
| Lead Investigator: | Ellie Choi |
| Contributors | Jose M Valderas |
Chronic inflammatory skin diseases, such as psoriasis and eczema, put a massive strain on patient mental health and have a significant adverse effect on their quality of life. While the importance of psychotherapeutic interventions for dermatology patients has been increasingly recognised, there is still a large treatment gap and lack of access to mental healthcare for these patients.
The multidisciplinary team comprising dermatologists, psychatrists, psychologists and behavioural science experts from NUH and NUS have developed a psycho-behavioural intervention deployed via a mobile app. This has been pilot tested in 2025 and will be tested on a larger scale in a Randomised Controlled Trial (RCT) aims to test the effectiveness of an app designed to help patients manage the symptom burden associated with their dermatological conditions.
Development and Pilot Implementation of an Electronic Patient Reported Outcome Measure (ePROM) system to Guide Clinical Decision Making and Improve Efficiency of Consult
| Funder: | National University Health System |
|---|---|
| Duration: | 2024 - 2026 |
| Lead Investigator: | Ellie Choi |
| Contributors | Jose M Valderas |
With the aim of exploring the use of electronic patient-reported outcome measures (ePROMs) to help guide follow-up care for patients, this project has examined factors that influence uptake and tested strategies to support patient engagement. An ongoing pilot trial is evaluating how ePROMs can be used to support more flexible scheduling of routine outpatient dermatology visits. Early findings suggest that this approach may reduce unnecessary clinic visits and missed appointments, while maintaining high patient engagement and satisfaction.
Development of the WHO Patient Reported Experience Measures (PREMs) for Primary Care
Funder: World Health Organisation, National University of Singapore
Duration: 2024 – 2026
Lead Investigator: Jose M Valderas
Contributors: Marie Ng, Wee Ling Koh
This study aims to develop and assess the metric properties of a suite of tools for measuring patient experiences of care in primary care settings.
National burden of 12 mental disorders in member countries of the Association of Southeast Asian Nations (ASEAN): A systematic analysis of the Global Burden of disease (GBD) Study 2021
Funder: National University of Singapore
Duration: 2024 – 2025
Lead Investigator: Marie Ng
Contributors: Jose M Valderas, Wee Ling Koh
This study aims to compare GBD indicators for mental illness in the 10 countries included in ASEAN to highlight regional and national trends as well as identify populations with particular needs. Findings from the study will be useful for policy makers, researchers, and clinicians.
Database of Individual Patients' Experiences (DIPEx) - Colorectal Cancer (in collaboration with the NUHS Department of Family Medicine)
Funder: Singapore Primary Care Cancer Network (SPriNT)
Duration: 2024
Lead Investigator: Laurie Goldsmith
Contributors: Jose M Valderas, Merial Maniclang
Developing a system for the use of natural language for the robust measurement of health-related quality of life, self-reported health and related patient reported outcome measures
Funder: National University of Singapore
Duration: 2024 -2026
Lead Investigator: Jose M Valderas
Contributors: Ellie Choi, Arivazhagan Karunakaran
This study aims to combine national language processing and IRT models to support data collection of patient reported information using free text.
