About

Muscle Magnetic Therapy

An ever growing body of evidence has now convincingly shown that magnetic fields are an authentic developmental force that can be exploited for regenerative medicine as well as general clinical applications. Nonetheless, the correct manners to apply the magnetic field and the designing of magnetic field devices safe for specific applications is still in its infancy. To solve these issues is the mandate of the BICEPS laboratory. The BICEPS laboratory brings together state-of-the-art engineering and biological know how. We have already made headway in these areas for use in several globally important diseases and regenerative medicine applications.

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Brain

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Pancreas

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Bone

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Gut/Intestine/microbiome

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Muscle Magnetic Therapy

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Brown Fat

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White Fats

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Kidney

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Immune Cells

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Muscle Magnetic Therapy

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Brain

a0240a860d73fa38838f9c4351f99c54

Brown Fat

7c67a620eddccd09823baf911ec50ec7

Pancreas

2e7a265756b19cad551b8d26340f5cf2

White Fats

00641eba8b7545338f19c2b01ed99e9a

Bone

3257e2236288faff3f02da15c556bc33

Kidney

20999c89fdccdc09afa633ba5f17ec4a

Gut/Intestine/microbiome

9db2ab23a260f8bac3d8cd7b8268319c

Immune Cells

Regular physical activity can result in adaptive changes to the brain's structure and function, a phenomenon known as neuroplasticity. Furthermore, exercise has also been shown to reduce neuroinflammation. Synergistically, this can impact various brain functions including cognition, mental and motor function. The activation of skeletal muscles, either via exercise or magnetic field therapy can have a profound effect on overall brain function, promoting greater health and resilience to brain disorders.

Skeletal muscles are major insulin-responsive tissues. Insulin facilitates glucose uptake by muscle cells and promotes glycogen synthesis. Myokines produced by skeletal muscles during contraction can in turn impact pancreatic function. Myokines such as interleukin-6 (IL-6) and irisin, have been implicated in metabolic regulation and may influence pancreatic function indirectly. Exercise and magnetic field intervention have anti-inflammatory effects via muscles, which may contribute to improved pancreatic and muscle health.

Mechanical loading is an important aspect of bone health that promotes bone formation. Weight-bearing exercises have been shown to increase bone density by putting stress on the bones via muscle contractions. Myokines, which are cytokines produced by muscles during exercise and magnetic fields, can affect bone remodelling. Irisin and IGF-1 (insulin-like growth factor 1) are examples of myokines that have been shown to improve bone density.

Regular exercise has been shown to have a positive impact on the diversity and composition of the gut microbiome. The microbiome plays a crucial role in metabolizing dietary components, producing short-chain fatty acids (SCFAs), and influencing energy metabolism. Metabolic disorders such as obesity and insulin resistance have been associated with changes in the microbiome composition. Hence, modulation of the gut microbiome through exercise, magnetic field intervention, diet or via fecal microbiota transplantation (FMT) are key areas of exploration for potential therapeutic interventions in metabolic diseases.

Exercise can enhance brown fat activity, to benefit overall metabolic health. Brown fat, also known as brown adipose tissue (BAT), is a type of adipose tissue that generates heat and is associated with the release of healthful adipokines (adipose-secreted factors). Moreover BAT, unlike white adipose tissue (WAT), burns more calories to produce heat and help regulate body temperature. Activation of skeletal muscles either with exercise or magnetic fields promote the release of modulatory myokines such as irisin, which can stimulate brown fat activity to enhance metabolic health.

Regular exercise can help maintain a healthy body fat ratio by increasing muscle mass, this achieving a better body composition. Muscle and adipose tissues communicate metabolically through myokines and adipokines, respectively. The secretion of health promoting myokines can be achieved with either exercise or magnetic field exposure. Myokines such as adiponectin and irisin can improve insulin sensitivity and reduce inflammatory responses.

Myokines produced during exercise and magnetic field exposure can affect energy metabolism in a variety of tissues, including the kidneys. These signaling molecules may influence glucose metabolism, insulin sensitivity, and overall metabolic health. Both regular exercise and magnetic field therapy release anti-inflammatory myokines which may benefit kidney health.

Regular exercise has been shown to benefit the immune system. Acute exercise can cause transient changes in immune cell circulation and function. Magnetic field therapy, similar to chronic exercise, has been linked to a more balanced and resilient immune response. Contracting skeletal muscles release signaling molecules known as myokines. Some myokines, including interleukin-6 (IL-6) and IL-15, have immune-modulatory properties. They can influence immune cell activity, aid in the regulation of inflammation and perform immunosurveillance for signs of infection or abnormal cell proliferation.