PHM5013 – Precision Drug Discovery and Development
Course Overview
This course will introduce how advances in target identification and validation help in precision drug discovery and development. Here, we will discuss on drug discovery and development process and the involvement of big data omics and artificial intelligence in this process, guided by precision pharmacogenomics. With relevant industry partners, this module will integrated understanding of all aspects of precision drug discovery and development process ranging from pharmacogenetics to pharmacogenomics to pharmaco-omics.
Learning Outcomes
At the end of this course, the student will
- gain a better understanding and latest information on precision drug discovery and development.
- grasp novel paradigms and advanced knowledge on drug discovery using data sets and AI, development, and evaluation.
- understand drug discovery from target identification to clinical trials of precision medicine currently used.
- be informed on the latest development of biomarker screening pipeline for patient stratification, treatment selection and management of adverse effects.
Course Outline
- General Introduction about Drug Discovery and Development Process
- Role of Big Data OMICs / Artificial Intelligence (AI) for Drug Discovery/Development
- Precision Pharmacogenomics
- From Pharmacogenetics to Pharmacogenomics to Pharmaco-omics
- Artificial Intelligence and Machine Learning to predict drug response integrating diverse data.
- Pharmaco-Economics of Pharmacogenomics-Guided Drug Therapy
- Clinical Implementation of Pharmacogenomics
Course Requirements
Student must have taken the core course Human Genomics in Precision Medicine or any similar modules.