PHM5001 – Human Genomics in Precision Medicine
Course Overview
This course aims to provide students with a strong foundation of the role genetics in the entire pathway of Precision Medicine including
- Understanding the genetic basis of diseases
- Employing state-of-the-art OMICs and analytic tools to identify disease causing genes and biomarkers for disease diagnosis and prognosis
- Developing genetic and genomic strategies to treat and mitigate diseases
Learning Outcomes
At the end of this course, students will:
- Know how genetics/genomics play roles in different types of diseases including Inherited, Complex and Infectious Diseases
- Learn how modern OMICs and Analytic tools can be employed to identify disease biomarkers, predict, diagnose and prognose disease.
- Learn how genetic / genomic strategies can be developed to prevent / mitigate severity / treat disease.
- Learn how OMICs / Analytic tools or genetic/genomic strategies can be employed to identify, predict, diagnose, prognose, prevent, mitigate or treat disease.
Course Outline
- Introduction to Precision Medicine (PM)
- Genetic / Genomic Basis of Diseases
- Introduction to high throughput genomic PM OMIC tools
- Disease Genes Identification through Association Analyses with PM OMICs
- Disease Susceptibility/Prognosis Prediction based on genetic/genomic signatures with PM OMICs through Machine Learning.
- Introduction to genetic/genomic Disease Diagnosis
- Introduction to modern genetic PM tools to prevent / mitigate severity of disease – Genetic Vaccines
- Introduction to modern genetic PM tools to treat disease – Molecular and Gene Therapy