Our lab is interested in the following topics related to autophagy and cancer cell biology:
Autophagy: Regulatory Mechanisms and Biological Functions in Cancer
Autophagy is an evolutionally conserved cellular catabolic process whereby cellular proteins and organelles are engulfed to autophagosomes and eventually delivered to lysosomes for degradation. Our lab is interested to understand the basic mechanisms of autophagy, its involvement in cell death and cancer development, as well as to development novel cancer preventive and therapeutic strategies via modulation of autophagy.
The ongoing research programs related to autophagy study include the following:
Involvement of ROS and Oxidative Stress in Cell Death (Apoptotic and Non Apoptotic Cell Death)
Antioxidants and Natural Products as Anti-Cancer Agents