{"id":250,"date":"2021-11-06T12:08:24","date_gmt":"2021-11-06T04:08:24","guid":{"rendered":"https:\/\/qat-medicine.nus.edu.sg\/trp\/infectious-diseases\/?page_id=250"},"modified":"2024-08-21T13:03:44","modified_gmt":"2024-08-21T05:03:44","slug":"careers","status":"publish","type":"page","link":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/careers\/","title":{"rendered":"Careers"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"250\" class=\"elementor elementor-250\" data-elementor-post-type=\"page\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-5b52093 elementor-section-full_width elementor-section-height-default elementor-section-height-default\" data-id=\"5b52093\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-dacc3a4\" data-id=\"dacc3a4\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f1a7e6e elementor--h-position-center elementor--v-position-middle elementor-pagination-position-inside elementor-widget elementor-widget-slides\" data-id=\"f1a7e6e\" data-element_type=\"widget\" data-settings=\"{"navigation":"dots","autoplay_speed":6000,"transition":"fade","transition_speed":1000,"autoplay":"yes","infinite":"yes"}\" data-widget_type=\"slides.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor-pro - v3.16.0 - 20-09-2023 *\/\n.elementor-slides .swiper-slide-bg{background-size:cover;background-position:50%;background-repeat:no-repeat;min-width:100%;min-height:100%}.elementor-slides .swiper-slide-inner{background-repeat:no-repeat;background-position:50%;position:absolute;top:0;left:0;bottom:0;right:0;padding:50px;margin:auto}.elementor-slides .swiper-slide-inner,.elementor-slides .swiper-slide-inner:hover{color:#fff;display:flex}.elementor-slides .swiper-slide-inner .elementor-background-overlay{position:absolute;z-index:0;top:0;bottom:0;left:0;right:0}.elementor-slides .swiper-slide-inner .elementor-slide-content{position:relative;z-index:1;width:100%}.elementor-slides .swiper-slide-inner .elementor-slide-heading{font-size:35px;font-weight:700;line-height:1}.elementor-slides .swiper-slide-inner .elementor-slide-description{font-size:17px;line-height:1.4}.elementor-slides .swiper-slide-inner .elementor-slide-description:not(:last-child),.elementor-slides .swiper-slide-inner .elementor-slide-heading:not(:last-child){margin-bottom:30px}.elementor-slides .swiper-slide-inner .elementor-slide-button{border:2px solid #fff;color:#fff;background:transparent;display:inline-block}.elementor-slides .swiper-slide-inner .elementor-slide-button,.elementor-slides .swiper-slide-inner .elementor-slide-button:hover{background:transparent;color:inherit;text-decoration:none}.elementor--v-position-top .swiper-slide-inner{align-items:flex-start}.elementor--v-position-bottom .swiper-slide-inner{align-items:flex-end}.elementor--v-position-middle .swiper-slide-inner{align-items:center}.elementor--h-position-left .swiper-slide-inner{justify-content:flex-start}.elementor--h-position-right .swiper-slide-inner{justify-content:flex-end}.elementor--h-position-center .swiper-slide-inner{justify-content:center}body.rtl .elementor-widget-slides .elementor-swiper-button-next{left:10px;right:auto}body.rtl .elementor-widget-slides .elementor-swiper-button-prev{right:10px;left:auto}.elementor-slides-wrapper div:not(.swiper-slide)>.swiper-slide-inner{display:none}@media (max-width:767px){.elementor-slides .swiper-slide-inner{padding:30px}.elementor-slides .swiper-slide-inner .elementor-slide-heading{font-size:23px;line-height:1;margin-bottom:15px}.elementor-slides .swiper-slide-inner .elementor-slide-description{font-size:13px;line-height:1.4;margin-bottom:15px}}<\/style>\t\t<div class=\"elementor-swiper\">\n\t\t\t<div class=\"elementor-slides-wrapper elementor-main-swiper swiper\" dir=\"ltr\" data-animation=\"fadeInUp\">\n\t\t\t\t<div class=\"swiper-wrapper elementor-slides\">\n\t\t\t\t\t\t\t\t\t\t<div class=\"elementor-repeater-item-74e6a2a swiper-slide\"><div class=\"swiper-slide-bg\" role=\"img\"><\/div><div class=\"swiper-slide-inner\" ><div class=\"swiper-slide-contents\"><div class=\"elementor-slide-heading\">Career<\/div><div class=\"elementor-slide-description\">Join our dynamic team<\/div><\/div><\/div><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3d46477 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3d46477\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-11915eb\" data-id=\"11915eb\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f86611a elementor-align-left elementor-widget elementor-widget-breadcrumbs\" data-id=\"f86611a\" data-element_type=\"widget\" data-widget_type=\"breadcrumbs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<link rel=\"stylesheet\" href=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-content\/plugins\/elementor-pro\/assets\/css\/widget-theme-elements.min.css\"><p id=\"breadcrumbs\"><span><span><a href=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/\">Home<\/a><\/span><\/span><\/p>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ce2f053 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ce2f053\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-no\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-12b0b0b\" data-id=\"12b0b0b\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5411451 elementor-tabs-alignment-stretch elementor-tabs-view-horizontal elementor-widget elementor-widget-tabs\" data-id=\"5411451\" data-element_type=\"widget\" data-widget_type=\"tabs.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.16.0 - 17-10-2023 *\/\n.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tabs-wrapper{width:25%;flex-shrink:0}.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tab-desktop-title.elementor-active{border-right-style:none}.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tab-desktop-title.elementor-active:after,.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tab-desktop-title.elementor-active:before{height:999em;width:0;right:0;border-right-style:solid}.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tab-desktop-title.elementor-active:before{top:0;transform:translateY(-100%)}.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tab-desktop-title.elementor-active:after{top:100%}.elementor-widget-tabs.elementor-tabs-view-horizontal .elementor-tab-desktop-title{display:table-cell}.elementor-widget-tabs.elementor-tabs-view-horizontal .elementor-tab-desktop-title.elementor-active{border-bottom-style:none}.elementor-widget-tabs.elementor-tabs-view-horizontal .elementor-tab-desktop-title.elementor-active:after,.elementor-widget-tabs.elementor-tabs-view-horizontal .elementor-tab-desktop-title.elementor-active:before{bottom:0;height:0;width:999em;border-bottom-style:solid}.elementor-widget-tabs.elementor-tabs-view-horizontal .elementor-tab-desktop-title.elementor-active:before{right:100%}.elementor-widget-tabs.elementor-tabs-view-horizontal .elementor-tab-desktop-title.elementor-active:after{left:100%}.elementor-widget-tabs .elementor-tab-content,.elementor-widget-tabs .elementor-tab-title,.elementor-widget-tabs .elementor-tab-title:after,.elementor-widget-tabs .elementor-tab-title:before,.elementor-widget-tabs .elementor-tabs-content-wrapper{border:1px #d5d8dc}.elementor-widget-tabs .elementor-tabs{text-align:left}.elementor-widget-tabs .elementor-tabs-wrapper{overflow:hidden}.elementor-widget-tabs .elementor-tab-title{cursor:pointer;outline:var(--focus-outline,none)}.elementor-widget-tabs .elementor-tab-desktop-title{position:relative;padding:20px 25px;font-weight:700;line-height:1;border:solid transparent}.elementor-widget-tabs .elementor-tab-desktop-title.elementor-active{border-color:#d5d8dc}.elementor-widget-tabs .elementor-tab-desktop-title.elementor-active:after,.elementor-widget-tabs .elementor-tab-desktop-title.elementor-active:before{display:block;content:\"\";position:absolute}.elementor-widget-tabs .elementor-tab-desktop-title:focus-visible{border:1px solid #000}.elementor-widget-tabs .elementor-tab-mobile-title{padding:10px;cursor:pointer}.elementor-widget-tabs .elementor-tab-content{padding:20px;display:none}@media (max-width:767px){.elementor-tabs .elementor-tab-content,.elementor-tabs .elementor-tab-title{border-style:solid solid none}.elementor-tabs .elementor-tabs-wrapper{display:none}.elementor-tabs .elementor-tabs-content-wrapper{border-bottom-style:solid}.elementor-tabs .elementor-tab-content{padding:10px}}@media (min-width:768px){.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tabs{display:flex}.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tabs-wrapper{flex-direction:column}.elementor-widget-tabs.elementor-tabs-view-vertical .elementor-tabs-content-wrapper{flex-grow:1;border-style:solid solid solid none}.elementor-widget-tabs.elementor-tabs-view-horizontal .elementor-tab-content{border-style:none solid solid}.elementor-widget-tabs.elementor-tabs-alignment-center .elementor-tabs-wrapper,.elementor-widget-tabs.elementor-tabs-alignment-end .elementor-tabs-wrapper,.elementor-widget-tabs.elementor-tabs-alignment-stretch .elementor-tabs-wrapper{display:flex}.elementor-widget-tabs.elementor-tabs-alignment-center .elementor-tabs-wrapper{justify-content:center}.elementor-widget-tabs.elementor-tabs-alignment-end .elementor-tabs-wrapper{justify-content:flex-end}.elementor-widget-tabs.elementor-tabs-alignment-stretch.elementor-tabs-view-horizontal .elementor-tab-title{width:100%}.elementor-widget-tabs.elementor-tabs-alignment-stretch.elementor-tabs-view-vertical .elementor-tab-title{height:100%}.elementor-tabs .elementor-tab-mobile-title{display:none}}<\/style>\t\t<div class=\"elementor-tabs\">\n\t\t\t<div class=\"elementor-tabs-wrapper\" role=\"tablist\" >\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-8811\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-8811\" aria-expanded=\"false\"><img decoding=\"async\" src=\"\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/faculty-position.svg\" style=\"width: 100px;\"><br><br>Faculty Position<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-8812\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-8812\" aria-expanded=\"false\"><img decoding=\"async\" src=\"https:\/\/medicine.nus.edu.sg\/trp\/wp-content\/uploads\/sites\/7\/2022\/01\/research-position.svg\" style=\"width: 65px;\"><br><br>Research Position<\/div>\n\t\t\t\t\t\t\t\t\t<div id=\"elementor-tab-title-8813\" class=\"elementor-tab-title elementor-tab-desktop-title\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-8813\" aria-expanded=\"false\"><img decoding=\"async\" src=\"\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/graduate-students.svg\" style=\" width: 70px;\"><br><br>Graduate Students<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t\t<div class=\"elementor-tabs-content-wrapper\" role=\"tablist\" aria-orientation=\"vertical\">\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"true\" data-tab=\"1\" role=\"tab\" tabindex=\"0\" aria-controls=\"elementor-tab-content-8811\" aria-expanded=\"false\"><img decoding=\"async\" src=\"\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/faculty-position.svg\" style=\"width: 100px;\"><br><br>Faculty Position<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-8811\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-8811\" tabindex=\"0\" hidden=\"false\">\t\t<div data-elementor-type=\"section\" data-elementor-id=\"2582\" class=\"elementor elementor-2582\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0b9617e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0b9617e\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-3cd9f86\" data-id=\"3cd9f86\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7dd8900 elementor-widget elementor-widget-accordion\" data-id=\"7dd8900\" data-element_type=\"widget\" data-widget_type=\"accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.16.0 - 17-10-2023 *\/\n.elementor-accordion{text-align:left}.elementor-accordion .elementor-accordion-item{border:1px solid #d5d8dc}.elementor-accordion .elementor-accordion-item+.elementor-accordion-item{border-top:none}.elementor-accordion .elementor-tab-title{margin:0;padding:15px 20px;font-weight:700;line-height:1;cursor:pointer;outline:none}.elementor-accordion .elementor-tab-title .elementor-accordion-icon{display:inline-block;width:1.5em}.elementor-accordion .elementor-tab-title .elementor-accordion-icon svg{width:1em;height:1em}.elementor-accordion .elementor-tab-title .elementor-accordion-icon.elementor-accordion-icon-right{float:right;text-align:right}.elementor-accordion .elementor-tab-title .elementor-accordion-icon.elementor-accordion-icon-left{float:left;text-align:left}.elementor-accordion .elementor-tab-title .elementor-accordion-icon .elementor-accordion-icon-closed{display:block}.elementor-accordion .elementor-tab-title .elementor-accordion-icon .elementor-accordion-icon-opened,.elementor-accordion .elementor-tab-title.elementor-active .elementor-accordion-icon-closed{display:none}.elementor-accordion .elementor-tab-title.elementor-active .elementor-accordion-icon-opened{display:block}.elementor-accordion .elementor-tab-content{display:none;padding:15px 20px;border-top:1px solid #d5d8dc}@media (max-width:767px){.elementor-accordion .elementor-tab-title{padding:12px 15px}.elementor-accordion .elementor-tab-title .elementor-accordion-icon{width:1.2em}.elementor-accordion .elementor-tab-content{padding:7px 15px}}.e-con-inner>.elementor-widget-accordion,.e-con>.elementor-widget-accordion{width:var(--container-widget-width);--flex-grow:var(--container-widget-flex-grow)}<\/style>\t\t<div class=\"elementor-accordion\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1311\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-1311\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Assistant Professor, Associate Professor or Full Professor\u200b \u200b<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-1311\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-1311\">\t\t<div data-elementor-type=\"section\" data-elementor-id=\"6898\" class=\"elementor elementor-6898\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2fd3c93 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2fd3c93\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7336405\" data-id=\"7336405\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-80dd20a elementor-widget elementor-widget-text-editor\" data-id=\"80dd20a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.16.0 - 17-10-2023 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p>The Infectious Diseases Translational Research Programme (ID TRP), Yong Loo Lin School of Medicine, National University of Singapore (NUS), invites applications for two tenure track faculty positions at Assistant Professor, Associate Professor or Full Professor levels in respiratory viruses and vaccine development, respectively. We are interested in candidates working on respiratory viruses, particularly influenza virus, on infection biology and pathogenesis. For vaccine development, candidates with innovative platforms or approaches to bacterial or viral diseases will be considered. Experience with animal models and preclinical studies of vaccine development would be helpful. Candidates with excellent publication track records in these areas are encouraged to apply. <\/p>\n<p>The ID TRP is a 17-primary member programme, consisting of basic scientists and clinician scientists for seamless translation of research. ID TRP has strong expertise in bacterial antibiotic multidrug resistance and emerging viruses, covering epidemiology, molecular mechanisms, animal models and therapeutic and prophylactic interventions. Other areas including phage biology, pneumococcal infections and microbiome are also being actively developed under the programme.<\/p>\n<p>Successful applicants will join a vibrant research environment at the School of Medicine (https:\/\/medicine.nus.edu.sg\/). Facilities (including BSL3 and ABSL3) and research support are world-class.<\/p>\n<p>The university offers internationally competitive salary packages in Singapore\u2019s low tax environment. The School of Medicine is committed to the achievement of excellence and diversity among its faculty, and female and minority candidates are encouraged to apply for the positions. Interested, strong candidates should forward their detailed curriculum vitae along with a letter of intent describing their current expertise, research plans, career goals, teaching interests, and provide the names of 3-5 academic referees. Please send the application materials to: <\/p>\n<p>Chair, ID TRP Search Committee (c\/o Ms. Anjanadevi D\/O Supamaniam)<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-58eb70e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"58eb70e\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-fa5a9ff\" data-id=\"fa5a9ff\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e272b70 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"e272b70\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.16.0 - 17-10-2023 *\/\n.elementor-widget-image{text-align:center}.elementor-widget-image a{display:inline-block}.elementor-widget-image a img[src$=\".svg\"]{width:48px}.elementor-widget-image img{vertical-align:middle;display:inline-block}<\/style>\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"193\" height=\"174\" src=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/aeroplane.svg\" class=\"attachment-full size-full wp-image-2645\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b651c09 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"b651c09\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.16.0 - 17-10-2023 *\/\n.elementor-heading-title{padding:0;margin:0;line-height:1}.elementor-widget-heading .elementor-heading-title[class*=elementor-size-]>a{color:inherit;font-size:inherit;line-height:inherit}.elementor-widget-heading .elementor-heading-title.elementor-size-small{font-size:15px}.elementor-widget-heading .elementor-heading-title.elementor-size-medium{font-size:19px}.elementor-widget-heading .elementor-heading-title.elementor-size-large{font-size:29px}.elementor-widget-heading .elementor-heading-title.elementor-size-xl{font-size:39px}.elementor-widget-heading .elementor-heading-title.elementor-size-xxl{font-size:59px}<\/style><h4 class=\"elementor-heading-title elementor-size-default\">All applications<br>\nto send to: <\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-4446149\" data-id=\"4446149\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bb32dd1 elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"bb32dd1\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<link rel=\"stylesheet\" href=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-content\/plugins\/elementor\/assets\/css\/widget-icon-list.min.css\">\t\t<ul class=\"elementor-icon-list-items elementor-inline-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:mayvien@nus.edu.sg\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">anjana@nus.edu.sg<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"2\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-8812\" aria-expanded=\"false\"><img decoding=\"async\" src=\"https:\/\/medicine.nus.edu.sg\/trp\/wp-content\/uploads\/sites\/7\/2022\/01\/research-position.svg\" style=\"width: 65px;\"><br><br>Research Position<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-8812\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-8812\" tabindex=\"0\" hidden=\"hidden\">\t\t<div data-elementor-type=\"section\" data-elementor-id=\"2588\" class=\"elementor elementor-2588\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-736ed7c elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"736ed7c\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-fa2e531\" data-id=\"fa2e531\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4414319 elementor-widget elementor-widget-accordion\" data-id=\"4414319\" data-element_type=\"widget\" data-widget_type=\"accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-accordion\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-7131\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-7131\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Research Assistant (PI Dr Tan Chee Wah)<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-7131\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-7131\">\t\t<div data-elementor-type=\"section\" data-elementor-id=\"6403\" class=\"elementor elementor-6403\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b10df26 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b10df26\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2c52970\" data-id=\"2c52970\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2235557 elementor-widget elementor-widget-text-editor\" data-id=\"2235557\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p data-ccp-props=\"{"335551550":6,"335551620":6,"335559683":0,"335559685":0,"335559731":0,"335559737":0,"335562764":2,"335562765":0.9,"335562766":4,"335562767":10,"335562768":4,"335562769":0}\"><b><span data-usefontface=\"true\" data-contrast=\"none\">Job description<\/span><\/b><\/p>\n<p>We have a research assistant position in the Infectious Diseases Translational Research Programme at Yong Loo Lin School of Medicine at the National University of Singapore. We are seeking to hire a motivated candidate with backgrounds in virology, immunology, and molecular biology to work on pandemic preparedness-related projects. The project focuses on developing diagnostic tools to study the prevalence of highly pathogenic virus spillover in humans and animals, aiming to better understand the regional infectious viral disease threats.<\/p>\n<p><\/p>\n<p>The job scope includes designing, developing, and optimizing conditions for experiments and collaborating with the local and overseas infectious disease teams to test various factors that can improve the sensitivity of the diagnostic platform.<\/p>\n<p data-ccp-props=\"{"335551550":6,"335551620":6,"335559683":0,"335559685":0,"335559731":0,"335559737":0,"335562764":2,"335562765":0.9,"335562766":4,"335562767":10,"335562768":4,"335562769":0}\"><b><span data-usefontface=\"true\" data-contrast=\"none\">Qualifications:<\/span><\/b><\/p>\n<ul style=\"font-weight: 400\">\n<li>Bachelor’s degree in Biomedical Sciences, Biotechnology, Biomedical Engineering<\/li>\n<li>Experience in serology, cell culture techniques, microscopy, and data analysis is preferred. Prior experience with virology will be an advantage.<\/li>\n<li>Highly motivated with the ability to work independently as well as in a team<\/li>\n<li>Organized and responsible team member<\/li>\n<li>Good writing and verbal communication skills<\/li>\n<\/ul>\n<p data-ccp-props=\"{"335551550":6,"335551620":6,"335559683":0,"335559685":0,"335559731":0,"335559737":0,"335562764":2,"335562765":0.9,"335562766":4,"335562767":10,"335562768":4,"335562769":0}\">We regret that only shortlisted applicants will be notified.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-6b3d4cc elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6b3d4cc\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-d826e92\" data-id=\"d826e92\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-aacaa83 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"aacaa83\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"193\" height=\"174\" src=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/aeroplane.svg\" class=\"attachment-full size-full wp-image-2645\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4d773e7 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"4d773e7\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Please send CV and cover letter describing research experience and interests, and the names and email addresses of three references to: <\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-cecb305\" data-id=\"cecb305\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9fbc0a3 elementor-widget elementor-widget-heading\" data-id=\"9fbc0a3\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Dr Tan Chee Wah<\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4d15be3 elementor-icon-list--layout-inline elementor-widget__width-initial elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"4d15be3\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<ul class=\"elementor-icon-list-items elementor-inline-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:micas@nus.edu.sg\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">cheewah.tan@duke-nus.edu.sg<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\"><\/span>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a3fa411 elementor-widget elementor-widget-heading\" data-id=\"a3fa411\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/careers.nus.edu.sg\/NUS\/job\/YONG-LOO-LIN-SCH-OF-MEDICINE-Research-Assistant-%28Infectious-Diseases%29-Kent\/18555644\/\"><br>or apply online by clicking here <br><a href=\"https:\/\/careers.nus.edu.sg\/NUS\/job\/Research-Assistant-%28Infectious-Diseases%29\/16249544\/\">https:\/\/careers.nus.edu.sg<\/a><\/a><\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-7132\" class=\"elementor-tab-title\" data-tab=\"2\" role=\"button\" aria-controls=\"elementor-tab-content-7132\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Research Fellow (PI Assoc Prof Thai Tran)<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-7132\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"region\" aria-labelledby=\"elementor-tab-title-7132\">\t\t<div data-elementor-type=\"page\" data-elementor-id=\"6156\" class=\"elementor elementor-6156\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-dbacb3a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"dbacb3a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-14c08e9\" data-id=\"14c08e9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1f8d11a elementor-widget elementor-widget-text-editor\" data-id=\"1f8d11a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong style=\"font-size: 1rem\">Job Description<\/strong><\/p><p style=\"font-weight: 400\">The National University of Singapore is inviting applications for a Research Fellow position in the Infectious Diseases Translational Research Programme and Department of Physiology at the Yong Loo Lin School of Medicine. Our laboratory’s overarching research focus is investigating how the microenvironment interacts with lung cells and how dysregulation of this interaction contributes to lung disease pathophysiology, specifically asthma, respiratory infections, and lung cancer. The long-term goal of our research is to identify novel therapeutic targets for these diseases.<\/p><p><b>Qualifications<\/b><\/p><ul><li>PhD in Life Sciences or related disciplines with a background in lung and\/or infectious disease research<\/li><li>Preferably with experience in in vivo animal infection models and molecular biology<\/li><li>Ability to lead manuscript writing of publications arising from the research work<\/li><li>Strong communication skills, both written and verbal, and excellent facilitation and presentation skills<\/li><li>Strong troubleshooting and problem-solving abilities with evidence of being responsible<\/li><li>Able to work independently and in a team, have an investigative nature, and be self-motivated with initiative<\/li><\/ul><p>\u00a0<\/p><p style=\"font-weight: 400\">Interested candidates are to submit your application, indicating current\/expected salary, supported by a detailed CV (including personal particulars, academic and employment history, complete list of publications\/oral presentations and full contacts of 3 referees). We regret that only shortlisted applicants will be notified.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-d00ff7b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d00ff7b\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-04e6a19\" data-id=\"04e6a19\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f6a8304 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"f6a8304\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"193\" height=\"174\" src=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/aeroplane.svg\" class=\"attachment-full size-full wp-image-2645\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bdcf23e elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"bdcf23e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-medium\"><a href=\"https:\/\/www.mycareersfuture.gov.sg\/job\/sciences\/research-fellow-national-university-singapore-4c6c70e8ca7628f98977846e4947b7c5?source=MCF&event=Search\" target=\"_blank\">Please send CV to <br>A\/Prof Thai Tran at<\/a><\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-235784c\" data-id=\"235784c\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9f70d29 elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"9f70d29\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<ul class=\"elementor-icon-list-items elementor-inline-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:mayvien@nus.edu.sg\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">phstt@nus.edu.sg<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b31d0a4 elementor-widget elementor-widget-heading\" data-id=\"b31d0a4\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/careers.nus.edu.sg\/NUS\/job\/Research-Fellow-%28Dept-of-Physiology%29\/16056244\/\" target=\"_blank\">or apply online by clicking here https:\/\/careers.nus.edu.sg\n<\/a><\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-7133\" class=\"elementor-tab-title\" data-tab=\"3\" role=\"button\" aria-controls=\"elementor-tab-content-7133\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Research Fellow (PI Assoc Prof Tan Yee Joo)<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-7133\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"region\" aria-labelledby=\"elementor-tab-title-7133\">\t\t<div data-elementor-type=\"page\" data-elementor-id=\"5790\" class=\"elementor elementor-5790\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-dbacb3a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"dbacb3a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-14c08e9\" data-id=\"14c08e9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1f8d11a elementor-widget elementor-widget-text-editor\" data-id=\"1f8d11a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><strong style=\"font-size: 1rem\">Job Description<\/strong><\/p><p style=\"font-weight: 400\">A postdoctoral research fellow position is available in the laboratory of Tan Yee Joo which is part of the Infectious Diseases Translational Research Programme, Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore. The successful applicant will be involved in projects on virus-host interactions and study influenza virus and coronavirus.<b>\u00a0<\/b><\/p><p><b>Qualifications<\/b><\/p><ul><li>PhD in Biological Sciences, Biomedical Science or relevant fields.<\/li><li>Preferably with some post-doctoral experience<\/li><li>Experienced in virology and\/or cell culture methodologies<\/li><li>Experienced in common biochemical techniques including PCR, real-time PCR, Western blot and immunofluorescence assays<\/li><li>Experienced in mouse experimentation is preferred<\/li><li>Strong publication record in peer-reviewed journals.<\/li><li>Ability to work in a team and conduct independent research with good analytical, technical and problem-solving skills.<\/li><\/ul><p>\u00a0<\/p><p style=\"font-weight: 400\">Interested candidates are to submit a detailed CV that includes educational background, work history, publication list and the names and email contacts of three referees. We regret that only shortlisted applicants will be notified.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-d00ff7b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d00ff7b\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-04e6a19\" data-id=\"04e6a19\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f6a8304 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"f6a8304\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"193\" height=\"174\" src=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/aeroplane.svg\" class=\"attachment-full size-full wp-image-2645\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bdcf23e elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"bdcf23e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-medium\"><a href=\"https:\/\/www.mycareersfuture.gov.sg\/job\/sciences\/research-fellow-national-university-singapore-4c6c70e8ca7628f98977846e4947b7c5?source=MCF&event=Search\" target=\"_blank\">Please send CV to <br>Assoc Prof Tan Yee Joo at<\/a><\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-235784c\" data-id=\"235784c\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9f70d29 elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"9f70d29\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<ul class=\"elementor-icon-list-items elementor-inline-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:mayvien@nus.edu.sg\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">mictyj@nus.edu.sg<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b31d0a4 elementor-widget elementor-widget-heading\" data-id=\"b31d0a4\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/careers.nus.edu.sg\/job-invite\/20456\/\" target=\"_blank\">or apply online by clicking here https:\/\/careers.nus.edu.sg\n<\/a><\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-7134\" class=\"elementor-tab-title\" data-tab=\"4\" role=\"button\" aria-controls=\"elementor-tab-content-7134\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Research Fellow (PI Dr Qu Kun)<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-7134\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"4\" role=\"region\" aria-labelledby=\"elementor-tab-title-7134\">\t\t<div data-elementor-type=\"section\" data-elementor-id=\"4034\" class=\"elementor elementor-4034\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-dbacb3a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"dbacb3a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-14c08e9\" data-id=\"14c08e9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1f8d11a elementor-widget elementor-widget-text-editor\" data-id=\"1f8d11a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>The <em>Infectious Diseases Translational Research Programme<\/em> (ID TRP), Yong Loo Lin School of Medicine at NUS invites applications for a contract full time <b>Postdoctoral Research Fellow<\/b> position to study infection and transmission mechanisms of zoonotic viruses in the Infectious Diseases Translational Research Programme (ID TRP) and the Department of Biochemistry, Yong Loo Lin School of Medicine. The ID TRP is pooling efforts of prominent scientists from multiple disciplines and committed to human infectious diseases closely relevant to Singapore and the region. The Department of Biochemistry provides intimate support in lipidomics, bioinformatics and synthetic biology.<\/p><p>Appointments will be made on a three-year contract basis with the possibility of extension. The University, Programme and Department provide customised trainings and grant opportunities for early career researchers.<\/p><p>\u00a0<\/p><p><strong>Job Description<\/strong><\/p><p>Working in the group of Assistant Professor QU Kun at the ID TRP and the Department of Biochemistry, the Research Fellow will conduct a project aimed at studying the pathogenesis of viral infections at cellular and molecular levels, and developing novel vaccines and therapeutic targets. The Qu lab (https:\/\/medicine.nus.edu.sg\/bch\/faculty\/qu-kun\/) is funded by the start-up award of the NUS Presidential Young Professorship. We utilise biological techniques to produce virus particles and viral proteins, and visualise them in situ or in vitro using cryo-electron microscopy, cryo-electron tomography and subtomogram averaging.<\/p><p>\u00a0<\/p><p><b>Main Duties and\u00a0Responsibilities<\/b><\/p><ul><li>Carry out scientific research aimed at understanding the assembly and transmission mechanisms of zoonotic viruses including SARS-CoV-2 and Influenza;<\/li><li>Introduce and apply a wide range of techniques to study virus assembly and attachment;<\/li><li>Present scientific work at internal meetings and external conferences;<\/li><li>Draft scientific manuscripts and prepare high-quality images for publication;<\/li><li>Contribute to scientific discussions and assist with other duties in the lab;<\/li><li>Interact and collaborate with other members within the research team, across the programme, and from external groups;<\/li><li>Maintain a high standard of professional conduct and record keeping in accordance with scientific integrity, biosafety policies and procedures;<\/li><li>Report to and discuss with the PI to ensure the project is performed in accordance with good practice.<\/li><\/ul><p><b>\u00a0<\/b><\/p><p><b>Qualifications<\/b><\/p><p>The applicant must or should:<br \/>\u2022 Behave with scientific integrity and honesty;<br \/>\u2022 Hold a Ph.D. in Biochemistry, Bioengineering or related disciplines, or due to complete Ph.D. within 6 months;<br \/>\u2022 Have excellent expertise in protein engineering, including expression and purification;<br \/>\u2022 Have handy experience with microfluidics, biopolymers or other biomaterial characterization techniques;<br \/>\u2022 Be able to work independently and be passionate about science;<br \/>\u2022 Be able to communicate and work with others in an open manner.<\/p><p>Remuneration will be commensurate with the candidate\u2019s qualifications and experience.\u00a0Only shortlisted candidates will be notified.\u00a0<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-d00ff7b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d00ff7b\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-04e6a19\" data-id=\"04e6a19\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f6a8304 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"f6a8304\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"193\" height=\"174\" src=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/aeroplane.svg\" class=\"attachment-full size-full wp-image-2645\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bdcf23e elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"bdcf23e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-medium\"><a href=\"https:\/\/careers.nus.edu.sg\/job-invite\/15450\/\" target=\"_blank\">For full consideration, please apply online by clicking here or send the cover letter, CV, names and contact information of 3 references to: \n<\/a><\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-235784c\" data-id=\"235784c\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b31d0a4 elementor-widget elementor-widget-heading\" data-id=\"b31d0a4\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Dr QU Kun <br>Ms Mayvien Teo <\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9f70d29 elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"9f70d29\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<ul class=\"elementor-icon-list-items elementor-inline-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:kqu@nus.edu.sg\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">kqu@nus.edu.sg<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:mayvien@nus.edu.sg\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">mayvien@nus.edu.sg<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-7135\" class=\"elementor-tab-title\" data-tab=\"5\" role=\"button\" aria-controls=\"elementor-tab-content-7135\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Research Assistant (PI Assoc Prof Tan Yee Joo)<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-7135\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"5\" role=\"region\" aria-labelledby=\"elementor-tab-title-7135\">\t\t<div data-elementor-type=\"page\" data-elementor-id=\"5779\" class=\"elementor elementor-5779\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-b10df26 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"b10df26\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2c52970\" data-id=\"2c52970\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2235557 elementor-widget elementor-widget-text-editor\" data-id=\"2235557\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><b><span data-usefontface=\"true\" data-contrast=\"none\">Laboratory: A\/P Tan Yee Joo, Department of\u00a0<\/span><\/b><b><span data-usefontface=\"true\" data-contrast=\"none\">Microbiology & Immunology<\/span><\/b><\/p><p><span data-usefontface=\"true\" data-contrast=\"none\"><a href=\"https:\/\/medicine.nus.edu.sg\/mbio\/about-us\/our-people\/academic-staff\/tan-yee-joo.html\">(https:\/\/medicine.nus.edu.sg\/mbio\/about-us\/our-people\/academic-staff\/tan-yee-joo.html<\/a><\/span><span data-usefontface=\"true\" data-contrast=\"none\">)<\/span><\/p><p data-ccp-props=\"{\"><span data-usefontface=\"true\" data-contrast=\"none\">\u00a0<\/span><\/p><p data-ccp-props=\"{\"><b><span data-usefontface=\"true\" data-contrast=\"none\">Job description:<\/span><\/b><\/p><p style=\"margin: 0cm;font-size: medium;font-family: Calibri, sans-serif;color: #000000\">The National University of Singapore invites applications for Research Assistant in the Department of Microbiology and Immunology, Yong Loo Lin School of Medicine. The successful candidate will be expected to carry out projects in the area of virus-host interactions in the laboratory of Associate Professor Tan Yee Joo.<\/p><p data-ccp-props=\"{\"><b>Purpose of the post:<\/b><span style=\"color: #000000;font-family: Calibri, sans-serif;font-size: 14.666666984558105px;background-color: #ffffff\"><br \/><\/span><\/p><p style=\"margin: 0cm;font-size: medium;font-family: Calibri, sans-serif;color: #000000\">The appointee will be a Research Assistant working closely with a multi-disciplinary team including research scholars and research fellows in the field of virology.<\/p><p data-ccp-props=\"{\"><b><span data-usefontface=\"true\" data-contrast=\"none\">Main duties and responsibilities:<\/span><\/b><\/p><p style=\"margin: 0cm;font-size: medium;font-family: Calibri, sans-serif;color: #000000\">We are looking for an enthusiastic and motivated candidate who will be actively involved in performing bench work related to virology, protein chemistry and cell biology. The RA will be closely working with research scholars and research fellows. He\/she will be required to assist with any other laboratory duties as delegated by the PI.<\/p><p data-ccp-props=\"{\"><b>Qualifications:\u00a0<\/b><\/p><ul><li>At least a Bachelor’s degree (preferably with honours) in Biomedical Sciences or related fields<\/li><li>Excellent written and oral communication skills in English<\/li><li>Highly motivated, self-driven, and independent<\/li><li>Interested in science and be able to work well in a team<\/li><li>Prior experience with virology or protein chemistry or cell biology preferred<\/li><li>Willing to work with virus and mouse model<\/li><li>Able to assist in laboratory administrative and management tasks including procurement and safety issues.<\/li><\/ul><p class=\"MsoListParagraphCxSpFirst\" style=\"text-indent: -18.0pt\"><!--[endif]--><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-6b3d4cc elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6b3d4cc\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-d826e92\" data-id=\"d826e92\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-aacaa83 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"aacaa83\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"193\" height=\"174\" src=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/aeroplane.svg\" class=\"attachment-full size-full wp-image-2645\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4d773e7 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"4d773e7\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">Apply now at<\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-cecb305\" data-id=\"cecb305\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9fbc0a3 elementor-widget elementor-widget-heading\" data-id=\"9fbc0a3\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\"><a href=\"https:\/\/careers.nus.edu.sg\/job-invite\/20455\/\" target=\"_blank\">https:\/\/careers.nus.edu.sg<\/a><\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-7136\" class=\"elementor-tab-title\" data-tab=\"6\" role=\"button\" aria-controls=\"elementor-tab-content-7136\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Research Assistant (PI Dr Qu Kun)<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-7136\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"6\" role=\"region\" aria-labelledby=\"elementor-tab-title-7136\">\t\t<div data-elementor-type=\"page\" data-elementor-id=\"5871\" class=\"elementor elementor-5871\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-dbacb3a elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"dbacb3a\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-14c08e9\" data-id=\"14c08e9\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1f8d11a elementor-widget elementor-widget-text-editor\" data-id=\"1f8d11a\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><span style=\"font-size: 1rem\">The National University of Singapore invites applications for a <\/span><b style=\"font-size: 1rem\">Research Assistant<\/b><span style=\"font-size: 1rem\"> to study infection and transmission mechanisms of zoonotic viruses in the Infectious Diseases Translational Research Programme (ID TRP) and the Department of Biochemistry, Yong Loo Lin School of Medicine.<\/span><\/p>\n<p>Appointments will be made on a one-year contract basis with the possibility of extension. The PI supports the Research Assistant for scholarship or job applications in his\/her next career.<\/p>\n<p><\/p>\n<p><strong>Job Description<\/strong><\/p>\n<p>Working in the group of Assistant Professor QU Kun at the ID TRP and the Department of Biochemistry, the Research Assistant will participate in a project aimed at studying the pathogenesis of viral infections at cellular and molecular levels, and developing novel vaccines and therapeutic targets. The Qu lab (https:\/\/medicine.nus.edu.sg\/bch\/faculty\/qu-kun\/) is funded by the start-up award of the NUS Presidential Young Professorship. We utilise biological techniques to produce virus particles and viral proteins, and visualise them in situ or in vitro using cryo-electron microscopy, cryo-electron tomography and subtomogram averaging.<\/p>\n<p><\/p>\n<p><b>Main Duties and Responsibilities<\/b><\/p>\n<ul>\n<li>The Research Assistant will be actively involved in (A) performing wet-lab experiment related to virology and protein chemistry, or (B) electron micrograph acquisition and processing.<\/li>\n<li>The Research Assistant will obtain one-to-one training with the principal investigator and other senior scientists, and then assist closely with ongoing research projects.<\/li>\n<li>The Research Assistant will take responsibilities for administrative tasks, handle the purchase of equipment and consumables.<\/li>\n<\/ul>\n<p><b> <\/b><\/p>\n<p><b>Qualifications<\/b><\/p>\n<p>The applicant must or should:<br><\/p>\n<ul>\n<li>Behave with scientific integrity and honesty;<\/li>\n<li>Hold a bachelor\u2019s degree (preferably with honours) in (A) Biology or Biotechnology, (B) Physics or Engineering, or related fields;<\/li>\n<li>Preferably have prior experience in (A) cell culture or protein purification, (B) microscopy or computer programming;<\/li>\n<li>Be passionate about science, have an investigative nature and attention to detail;<\/li>\n<li>Be highly motivated, self-driven, and independent;<\/li>\n<li>Be able to communicate and work with others in an open manner.<\/li>\n<\/ul>\n<p><br><\/p><p>Remuneration will be commensurate with the candidate\u2019s qualifications and experience. Only shortlisted candidates will be notified. <\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-d00ff7b elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d00ff7b\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-04e6a19\" data-id=\"04e6a19\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-f6a8304 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"f6a8304\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"193\" height=\"174\" src=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/aeroplane.svg\" class=\"attachment-full size-full wp-image-2645\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-bdcf23e elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"bdcf23e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-medium\"><a href=\"https:\/\/careers.nus.edu.sg\/NUS\/job\/YONG-LOO-LIN-SCH-OF-MEDICINE-Research-Assistant%28Infectious-Diseases-Translational-Research-Programme%29-Kent\/12085544\/\" target=\"_blank\">For full consideration, please apply online by clicking here or send the cover letter, CV, names and contact information of 3 references to: \n<\/a><\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-235784c\" data-id=\"235784c\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b31d0a4 elementor-widget elementor-widget-heading\" data-id=\"b31d0a4\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Dr QU Kun <br>Ms Mayvien Teo <\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9f70d29 elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"9f70d29\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<ul class=\"elementor-icon-list-items elementor-inline-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:kqu@nus.edu.sg\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">kqu@nus.edu.sg<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:mayvien@nus.edu.sg\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">mayvien@nus.edu.sg<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t\t\t<div class=\"elementor-tab-title elementor-tab-mobile-title\" aria-selected=\"false\" data-tab=\"3\" role=\"tab\" tabindex=\"-1\" aria-controls=\"elementor-tab-content-8813\" aria-expanded=\"false\"><img decoding=\"async\" src=\"\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/graduate-students.svg\" style=\" width: 70px;\"><br><br>Graduate Students<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-8813\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"tabpanel\" aria-labelledby=\"elementor-tab-title-8813\" tabindex=\"0\" hidden=\"hidden\">\t\t<div data-elementor-type=\"section\" data-elementor-id=\"2594\" class=\"elementor elementor-2594\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-0abcf64 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"0abcf64\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d0c13fc\" data-id=\"d0c13fc\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-9513ba9 elementor-widget elementor-widget-accordion\" data-id=\"9513ba9\" data-element_type=\"widget\" data-widget_type=\"accordion.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<div class=\"elementor-accordion\">\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1561\" class=\"elementor-tab-title\" data-tab=\"1\" role=\"button\" aria-controls=\"elementor-tab-content-1561\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Molecular RNA Virology and Antiviral Strategies (MARVAS)\u00a0<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-1561\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"1\" role=\"region\" aria-labelledby=\"elementor-tab-title-1561\">\t\t<div data-elementor-type=\"section\" data-elementor-id=\"3986\" class=\"elementor elementor-3986\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-74572cc elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"74572cc\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d880263\" data-id=\"d880263\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6cfb3f8 elementor-widget elementor-widget-text-editor\" data-id=\"6cfb3f8\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p><b>Molecular RNA Virology and Antiviral Strategies (MARVAS)\u00a0<\/b><\/p><p>Positive-strand RNA viruses encompass over one-third of all virus genera and include numerous human pathogens, such\u00a0as dengue virus, West Nile virus, Enterovirus 71, Chikungunya virus, MERS coronavirus and hepatitis C virus. Host factors\u00a0participate in most, if not all steps of positive-strand RNA virus infection, including entry, viral gene expression, virion\u00a0assembly and release. Moreover, host factors are targeted by positive-strand RNA viruses to modulate host gene\u00a0expression and immune\u00a0defenses. In our current study, human Enterovirus 71, mosquito-borne viruses (Zika and\u00a0Dengue) as well as SARS CoV-2 are used as the virus models to decipher the interplay of essential host factors with\u00a0positive-strand RNA viruses. Knowledge gained from these investigations has enabled us to design and develop the\u00a0formulation of effective vaccine or therapeutic intervention (antivirals) against these medically important virus\u00a0infections.\u00a0<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-2aa0c33 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2aa0c33\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-280582d\" data-id=\"280582d\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b083c36 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"b083c36\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"193\" height=\"174\" src=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/aeroplane.svg\" class=\"attachment-full size-full wp-image-2645\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-f2245ed elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"f2245ed\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">All applications<br>\nto send to: <\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-64bdd04\" data-id=\"64bdd04\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-0e74703 elementor-widget elementor-widget-heading\" data-id=\"0e74703\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">A\/Prof Chu Jang Hann<\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6b57969 elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"6b57969\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<ul class=\"elementor-icon-list-items elementor-inline-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:miccjh@nus.edu.sg\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">miccjh@nus.edu.sg<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-dc37993 elementor-widget elementor-widget-heading\" data-id=\"dc37993\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">Department of Microbiology & Immunology\u00a0\n<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1562\" class=\"elementor-tab-title\" data-tab=\"2\" role=\"button\" aria-controls=\"elementor-tab-content-1562\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Elucidating capsular polysaccharide biogenesis in Streptococcus pneumoniae<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-1562\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"2\" role=\"region\" aria-labelledby=\"elementor-tab-title-1562\">\t\t<div data-elementor-type=\"section\" data-elementor-id=\"3997\" class=\"elementor elementor-3997\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1d1afdc elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1d1afdc\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-55745f2\" data-id=\"55745f2\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-07d6ba9 elementor-widget elementor-widget-text-editor\" data-id=\"07d6ba9\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Streptococcus pneumoniae is an important respiratory pathogen that causes more than one million deaths worldwide annually. Similar to other pathogenic bacteria, S. pneumoniae encases its cell envelope with capsular polysaccharide (CPS). This layer protects the cell from host insults, such as opsonophagocytosis and mucus clearance. Because of its importance in pathogenesis, all clinically relevant vaccines against S. pneumoniae target the CPS. There are at least 100 serotypes identified and the structural variation of CPS is attributed to the extreme diversity of glycosyltransferases (GTs), flippases, and polymerases at the cps locus. Little is known about the molecular mechanisms governing their specificity, regulation, and function. The long-term goal of this project is to\u00a0investigate the specificity determinants of CPS enzymes based on the wealth of structural information available for\u00a0pneumococcal CPS. Our approach is enabled by conditional essentiality of the CPS enzymes and the genetic tractability of S. pneumoniae.\u00a0<\/p><p>Understanding how CPSs are synthesized in S. pneumoniae is critical to improve our current antimicrobial and vaccine strategies. Enzyme variants isolated from this work will be valuable tools for synthetic biology and glycoengineering. Besides studying CPS enzymes, we are interested in finding small molecules that inhibit different steps of the CPS pathway as therapeutics.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-d5a48b0 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"d5a48b0\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-52c0950\" data-id=\"52c0950\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-00ce2f0 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"00ce2f0\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"193\" height=\"174\" src=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/aeroplane.svg\" class=\"attachment-full size-full wp-image-2645\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-924feb8 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"924feb8\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">All applications<br>\nto send to: <\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-b89e005\" data-id=\"b89e005\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-3b7a0e8 elementor-widget elementor-widget-heading\" data-id=\"3b7a0e8\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">Dr Sham Lok To, Chris <\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-b13e2f3 elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"b13e2f3\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<ul class=\"elementor-icon-list-items elementor-inline-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:miclts@nus.edu.sg\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">miclts@nus.edu.sg<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-86343a8 elementor-widget elementor-widget-heading\" data-id=\"86343a8\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">Department of Microbiology & Immunology\u00a0\n<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1563\" class=\"elementor-tab-title\" data-tab=\"3\" role=\"button\" aria-controls=\"elementor-tab-content-1563\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Applying single cell genomics to gain new insights into recurrent urinary tract infection, potentially leading to novel treatment strategies<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-1563\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"3\" role=\"region\" aria-labelledby=\"elementor-tab-title-1563\">\t\t<div data-elementor-type=\"section\" data-elementor-id=\"4003\" class=\"elementor elementor-4003\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-89f3a73 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"89f3a73\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-98285bb\" data-id=\"98285bb\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-e8ad9ff elementor-widget elementor-widget-text-editor\" data-id=\"e8ad9ff\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Urinary tract infections (UTIs) are among the most common infections of humans and a major reason why people take antibiotics. This, in turn, leads to higher antibiotic resistance rates. The primary clinical problem in treating UTI is that for some patients, UTIs recur frequently, despite sometimes prolonged courses of antibiotic therapy. While the majority of bacteria during a UTI are extracellular and present in the urine in the lumen of the bladder (which makes them easy to isolate, monitor, and treat), a subset of intracellular bacteria within the bladder epithelial cells is relatively resistant to antibiotic treatment and host immune defenses. These intracellular bacteria can therefore persist for weeks to months in the bladder (presumably causing no symptoms); upon reactivation, they can cause recurrent UTI. We are applying advances in single cell genomics to understand how UPEC are able to enter and survive in the intracellular niche. Some of our genetic and protein engineering tools are crucial for this work, enabling us to manipulate and visualize clinical strains of UPEC<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-9f442bd elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"9f442bd\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-d320494\" data-id=\"d320494\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2739b8d elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"2739b8d\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"193\" height=\"174\" src=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/aeroplane.svg\" class=\"attachment-full size-full wp-image-2645\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-88cce0f elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"88cce0f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">All applications<br>\nto send to: <\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-3de4b92\" data-id=\"3de4b92\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8233986 elementor-widget elementor-widget-heading\" data-id=\"8233986\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">A\/Prof Swaine Chen\u00a0<\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a0f8003 elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"a0f8003\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<ul class=\"elementor-icon-list-items elementor-inline-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:mdcslc@nus.edu.sg\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">mdcslc@nus.edu.sg<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-d650ebe elementor-widget elementor-widget-heading\" data-id=\"d650ebe\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">Department of Medicine\u00a0<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1564\" class=\"elementor-tab-title\" data-tab=\"4\" role=\"button\" aria-controls=\"elementor-tab-content-1564\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Developing sexual genetics in E. coli as a new, complimentary engine for synthetic biology applications\u00a0<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-1564\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"4\" role=\"region\" aria-labelledby=\"elementor-tab-title-1564\">\t\t<div data-elementor-type=\"section\" data-elementor-id=\"4007\" class=\"elementor elementor-4007\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-8750d38 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"8750d38\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d3e0bb3\" data-id=\"d3e0bb3\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-b97b51d elementor-widget elementor-widget-text-editor\" data-id=\"b97b51d\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Genetics has been a cornerstone of biological discovery, leading to understanding, diagnosis, and treatments for numerous human diseases. The history of genetics traces its roots to Gregor Mendel\u2019s iconic experiments hybridizing pea plants; a direct line to powerful genetic systems in Drosophila and mice has enabled breakthroughs ranging from congenital disease to cancer.\u00a0<\/p><p>The Chen lab has developed several genetic techniques, in particular focusing on general tools that can be used in wild-type strains of E. coli in addition to the \u201ceasier\u201d lab-adapted strains traditionally used for synthetic biology. These tools now, for the first time, enable access to the power of sexual genetics (like that which powers mouse or human genetic studies) combined with high throughput genomics in Escherichia coli, the most well studied bacterium and most important chassis organism for synthetic biology. The marriage of sexual genetics with E. coli enables unprecedented opportunities for research discovery (which requires a robust resource supply chain) and for developing and marketing boutique, purpose-built custom chassis for the broader biotechnology industry.<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-c8845d4 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"c8845d4\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-2dddfab\" data-id=\"2dddfab\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8bc330d elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"8bc330d\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"193\" height=\"174\" src=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/aeroplane.svg\" class=\"attachment-full size-full wp-image-2645\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a06e860 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"a06e860\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">All applications<br>\nto send to: <\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-5e6b42e\" data-id=\"5e6b42e\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-2cad91a elementor-widget elementor-widget-heading\" data-id=\"2cad91a\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">A\/Prof Swaine Chen\u00a0\n<\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-625a5a2 elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"625a5a2\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<ul class=\"elementor-icon-list-items elementor-inline-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:mdcslc@nus.edu.sg\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">mdcslc@nus.edu.sg<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-563a843 elementor-widget elementor-widget-heading\" data-id=\"563a843\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">Department of Medicine<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1565\" class=\"elementor-tab-title\" data-tab=\"5\" role=\"button\" aria-controls=\"elementor-tab-content-1565\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Explaining the 2015 GBS yu sheng outbreak in Singapore – and ongoing GBS infections<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-1565\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"5\" role=\"region\" aria-labelledby=\"elementor-tab-title-1565\">\t\t<div data-elementor-type=\"section\" data-elementor-id=\"4013\" class=\"elementor elementor-4013\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-594d497 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"594d497\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-10b75dd\" data-id=\"10b75dd\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-a9d5fbc elementor-widget elementor-widget-text-editor\" data-id=\"a9d5fbc\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>The largest reported outbreak of group B Streptococcus (GBS) infections occurred in Singapore in 2015, involving over 300 cases of bloodstream infections. This outbreak was associated with consumption of \u9b5a\u751f (yu sheng), a dish made from sliced raw fish and served with rice porridge by food stalls. Such foodborne transmission leading to invasive disease had not been reported prior to this outbreak. One clone of GBS, referred to as ST283, was responsible for this outbreak; this strain is almost exclusively found in Southeast Asia in both humans and fish. This project uses genomics, genetics, microbiology, and an animal model of infection to discover why ST283 GBS is so proficient at causing disease in humans and why it is well adapted to aquaculture.\u00a0<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-6a38aba elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"6a38aba\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-ba839cf\" data-id=\"ba839cf\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4d60593 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"4d60593\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"193\" height=\"174\" src=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/aeroplane.svg\" class=\"attachment-full size-full wp-image-2645\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-be5c549 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"be5c549\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">All applications<br>\nto send to: <\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-c800547\" data-id=\"c800547\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-853e85e elementor-widget elementor-widget-heading\" data-id=\"853e85e\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">A\/Prof Swaine Chen\u00a0\n<\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6d56b24 elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"6d56b24\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<ul class=\"elementor-icon-list-items elementor-inline-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:mdcslc@nus.edu.sg\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">mdcslc@nus.edu.sg<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-9c250ce elementor-widget elementor-widget-heading\" data-id=\"9c250ce\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">Department of Medicine\u00a0<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1566\" class=\"elementor-tab-title\" data-tab=\"6\" role=\"button\" aria-controls=\"elementor-tab-content-1566\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Studying viral-host interactions in chronic hepatitis viral infection versus acute viral infection by newly emerged viruses<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-1566\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"6\" role=\"region\" aria-labelledby=\"elementor-tab-title-1566\">\t\t<div data-elementor-type=\"section\" data-elementor-id=\"4023\" class=\"elementor elementor-4023\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ba03a49 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ba03a49\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-80967d0\" data-id=\"80967d0\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c752a3f elementor-widget elementor-widget-text-editor\" data-id=\"c752a3f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Approximately 2 billion people have been infected by two viruses, hepatitis B virus (HBV) and hepatitis C virus (HCV), which primarily attack the liver. Although HCV and HBV are completely different viruses, both of them preferentially infect hepatocytes and are able to subvert the innate and adaptive immunity, leading to chronic infection. In contrast, acute infection happens for many newly emerged viruses, like influenza A virus and coronavirus, after zoonotic transmission. For all these viruses, the complex interplay between viral proteins and host cell machineries contributes to viral replication and\/or pathogenesis. However, the exact manner by which each virus participates in this complex process is not completely understood. In this project, we will use a multidisciplinary approach to identify host factors that are regulated by different viral proteins. The functional significance of novel viral-host interactions identified will be analyzed by using cell culture systems. Identification of novel viral-host interaction therefore offers opportunities for designing new treatments and prevention strategies.\u00a0<\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-a7de9bc elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a7de9bc\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-89bb4fd\" data-id=\"89bb4fd\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bf5d8b2 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"bf5d8b2\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"193\" height=\"174\" src=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/aeroplane.svg\" class=\"attachment-full size-full wp-image-2645\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-15068a4 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"15068a4\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">All applications<br>\nto send to: <\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-661c8b9\" data-id=\"661c8b9\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8aa3b1f elementor-widget elementor-widget-heading\" data-id=\"8aa3b1f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">A\/Prof Tan Yee Joo\u00a0\n<\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1001a9f elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"1001a9f\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<ul class=\"elementor-icon-list-items elementor-inline-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:mictyj@nus.edu.sg\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">mictyj@nus.edu.sg<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-65b05bf elementor-widget elementor-widget-heading\" data-id=\"65b05bf\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">Department of Microbiology & Immunology\u00a0\n<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t<div class=\"elementor-accordion-item\">\n\t\t\t\t\t<div id=\"elementor-tab-title-1567\" class=\"elementor-tab-title\" data-tab=\"7\" role=\"button\" aria-controls=\"elementor-tab-content-1567\" aria-expanded=\"false\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon elementor-accordion-icon-right\" aria-hidden=\"true\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-closed\"><svg class=\"e-font-icon-svg e-fas-plus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H272V64c0-17.67-14.33-32-32-32h-32c-17.67 0-32 14.33-32 32v144H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h144v144c0 17.67 14.33 32 32 32h32c17.67 0 32-14.33 32-32V304h144c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t<span class=\"elementor-accordion-icon-opened\"><svg class=\"e-font-icon-svg e-fas-minus\" viewBox=\"0 0 448 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M416 208H32c-17.67 0-32 14.33-32 32v32c0 17.67 14.33 32 32 32h384c17.67 0 32-14.33 32-32v-32c0-17.67-14.33-32-32-32z\"><\/path><\/svg><\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t\t\t<a class=\"elementor-accordion-title\" tabindex=\"0\">Achieving Functional Cure of Chronic Hepatitis B<\/a>\n\t\t\t\t\t<\/div>\n\t\t\t\t\t<div id=\"elementor-tab-content-1567\" class=\"elementor-tab-content elementor-clearfix\" data-tab=\"7\" role=\"region\" aria-labelledby=\"elementor-tab-title-1567\"><div class=\"page\" title=\"Page 20\"><div class=\"section\"><div class=\"layoutArea\"><div class=\"column\"><p style=\"text-align: justify;\">\t\t<div data-elementor-type=\"page\" data-elementor-id=\"5473\" class=\"elementor elementor-5473\" data-elementor-post-type=\"elementor_library\">\n\t\t\t\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-ba03a49 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"ba03a49\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-80967d0\" data-id=\"80967d0\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-c752a3f elementor-widget elementor-widget-text-editor\" data-id=\"c752a3f\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p style=\"caret-color: #000000; color: #000000; text-align: justify;\">Chronic Hepatitis B is chronic viral disease affecting the liver and there are over 270million infected patients globally, being the most common cause of liver disease and liver cancer globally. Functional cure (HBsAg loss) is an achievable goal leading to improved survival, lower liver cancer and liver complications.<\/p><div class=\"page\" style=\"caret-color: #000000; color: #000000;\" title=\"Page 21\"><div class=\"section\"><div class=\"layoutArea\"><div class=\"column\"><p style=\"text-align: justify;\">The biology of different stages of Chronic Hepatitis B (CHB) is still not well understood but insights are likely with deep multidimensional phenotyping comprising genomics, transcriptomics, proteomics , microRNA, immunology and virological characterisation, an opportunity we are well placed to explore with our well established cohort of over 2000 Chronic Hepatitis B patients The main focus will be on functional cure of CHB defined as HBsAg loss, not achievable with current therapies.<\/p><p style=\"text-align: justify;\">The objectives of our proposal is the understand the virological and immune mechanisms involved in functional cure by examining the liver microenvironment with state of the art technologies such as single cell analysis, genomics, transcriptomics, proteomics, and epigenetics in patients with\/without functional cure. As the key to CHB is an indepth analysis of epigenetics of cccDNA, factors found in the HBV TCR to be important in viral replication will be investigated to understand their direct or indirect relationship to HBV. Concurrently, a validated target for HBV will be a particular focus for assay development, computerised modelling, and medicinal library development as possible new classes of antiviral agents. New mechanisms of action, and new antiviral agents can be tested out in the humanised mouse model which is being developed as a model-of-choice for CHB with chronic HBV infected hepatocytes and a fully matched immune system.<\/p><p style=\"text-align: justify;\">Potential projects for suitable applicants, esp those interested in PhD projects<\/p><p style=\"text-align: justify;\">1. Transcriptome analysis of intrahepatic versus peripheral blood compartment in CHB patients with and without functional cure<\/p><p style=\"text-align: justify;\">2. Functional immunological analysis of intrahepatic compared to peripheral blood in functional cure<\/p><p style=\"text-align: justify;\">3. Innate versus adaptive intrahepatic immune responses in CHB patients with and without functional cure<\/p><p style=\"text-align: justify;\">4. Examination of HBV minichrosome (cccDNA)quantity and function in CHB livers in patients with and without functional cure 5. Dissecting cccDNA silencing mechanisms in patients with and without functional cure of CHB<\/p><p style=\"text-align: justify;\">6. Assay development in novel targets towards HBV<\/p><p style=\"text-align: justify;\">7. Medicinal library construction of potential antiviral agents using novel targets and assays<\/p><p style=\"text-align: justify;\">8. Humanised mice models for Chronic hepatitis B<\/p><\/div><\/div><\/div><\/div>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<section class=\"elementor-section elementor-inner-section elementor-element elementor-element-a7de9bc elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"a7de9bc\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-89bb4fd\" data-id=\"89bb4fd\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-bf5d8b2 elementor-widget__width-initial elementor-widget elementor-widget-image\" data-id=\"bf5d8b2\" data-element_type=\"widget\" data-widget_type=\"image.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<img decoding=\"async\" width=\"193\" height=\"174\" src=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-content\/uploads\/sites\/7\/2022\/01\/aeroplane.svg\" class=\"attachment-full size-full wp-image-2645\" alt=\"\" loading=\"lazy\" \/>\t\t\t\t\t\t\t\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-15068a4 elementor-widget__width-initial elementor-widget elementor-widget-heading\" data-id=\"15068a4\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h4 class=\"elementor-heading-title elementor-size-default\">All applications<br>\nto send to: <\/h4>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<div class=\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-661c8b9\" data-id=\"661c8b9\" data-element_type=\"column\" data-settings=\"{"background_background":"classic"}\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t\t\t<div class=\"elementor-element elementor-element-8aa3b1f elementor-widget elementor-widget-heading\" data-id=\"8aa3b1f\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h5 class=\"elementor-heading-title elementor-size-default\">A\/Prof Tan Yee Joo\u00a0\n<\/h5>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1001a9f elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\" data-id=\"1001a9f\" data-element_type=\"widget\" data-widget_type=\"icon-list.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t<ul class=\"elementor-icon-list-items elementor-inline-items\">\n\t\t\t\t\t\t\t<li class=\"elementor-icon-list-item elementor-inline-item\">\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"mailto:mictyj@nus.edu.sg\">\n\n\t\t\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-icon\">\n\t\t\t\t\t\t\t<svg aria-hidden=\"true\" class=\"e-font-icon-svg e-fas-envelope\" viewBox=\"0 0 512 512\" xmlns=\"http:\/\/www.w3.org\/2000\/svg\"><path d=\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\"><\/path><\/svg>\t\t\t\t\t\t<\/span>\n\t\t\t\t\t\t\t\t\t\t<span class=\"elementor-icon-list-text\">mictyj@nus.edu.sg<\/span>\n\t\t\t\t\t\t\t\t\t\t\t<\/a>\n\t\t\t\t\t\t\t\t\t<\/li>\n\t\t\t\t\t\t<\/ul>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-65b05bf elementor-widget elementor-widget-heading\" data-id=\"65b05bf\" data-element_type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<h6 class=\"elementor-heading-title elementor-size-default\">Department of Microbiology & Immunology\u00a0\n<\/h6>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/p><\/div><\/div><\/div><\/div><\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t\t\t\t\t\t<script type=\"application\/ld+json\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@type\":\"FAQPage\",\"mainEntity\":[{\"@type\":\"Question\",\"name\":\"Molecular RNA Virology and Antiviral Strategies (MARVAS)\\u00a0\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"\\t\\t<div data-elementor-type=\\\"section\\\" data-elementor-id=\\\"3986\\\" class=\\\"elementor elementor-3986\\\" data-elementor-post-type=\\\"elementor_library\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<section class=\\\"elementor-section elementor-top-section elementor-element elementor-element-74572cc elementor-section-boxed elementor-section-height-default elementor-section-height-default\\\" data-id=\\\"74572cc\\\" data-element_type=\\\"section\\\">\\n\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-container elementor-column-gap-default\\\">\\n\\t\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d880263\\\" data-id=\\\"d880263\\\" data-element_type=\\\"column\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-6cfb3f8 elementor-widget elementor-widget-text-editor\\\" data-id=\\\"6cfb3f8\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"text-editor.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t\\t\\t<p><b>Molecular RNA Virology and Antiviral Strategies (MARVAS)\\u00a0<\\\/b><\\\/p><p>Positive-strand RNA viruses encompass over one-third of all virus genera and include numerous human pathogens, such\\u00a0as dengue virus, West Nile virus, Enterovirus 71, Chikungunya virus, MERS coronavirus and hepatitis C virus. Host factors\\u00a0participate in most, if not all steps of positive-strand RNA virus infection, including entry, viral gene expression, virion\\u00a0assembly and release. Moreover, host factors are targeted by positive-strand RNA viruses to modulate host gene\\u00a0expression and immune\\u00a0defenses. In our current study, human Enterovirus 71, mosquito-borne viruses (Zika and\\u00a0Dengue) as well as SARS CoV-2 are used as the virus models to decipher the interplay of essential host factors with\\u00a0positive-strand RNA viruses. Knowledge gained from these investigations has enabled us to design and develop the\\u00a0formulation of effective vaccine or therapeutic intervention (antivirals) against these medically important virus\\u00a0infections.\\u00a0<\\\/p>\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<section class=\\\"elementor-section elementor-inner-section elementor-element elementor-element-2aa0c33 elementor-section-boxed elementor-section-height-default elementor-section-height-default\\\" data-id=\\\"2aa0c33\\\" data-element_type=\\\"section\\\">\\n\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-container elementor-column-gap-default\\\">\\n\\t\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-280582d\\\" data-id=\\\"280582d\\\" data-element_type=\\\"column\\\" data-settings=\\\"{"background_background":"classic"}\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-b083c36 elementor-widget__width-initial elementor-widget elementor-widget-image\\\" data-id=\\\"b083c36\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"image.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<img width=\\\"193\\\" height=\\\"174\\\" src=\\\"https:\\\/\\\/medicine.nus.edu.sg\\\/trp\\\/infectious-diseases\\\/wp-content\\\/uploads\\\/sites\\\/7\\\/2022\\\/01\\\/aeroplane.svg\\\" class=\\\"attachment-full size-full wp-image-2645\\\" alt=\\\"\\\" loading=\\\"lazy\\\" \\\/>\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-f2245ed elementor-widget__width-initial elementor-widget elementor-widget-heading\\\" data-id=\\\"f2245ed\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h4 class=\\\"elementor-heading-title elementor-size-default\\\">All applications<br>\\nto send to: <\\\/h4>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-64bdd04\\\" data-id=\\\"64bdd04\\\" data-element_type=\\\"column\\\" data-settings=\\\"{"background_background":"classic"}\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-0e74703 elementor-widget elementor-widget-heading\\\" data-id=\\\"0e74703\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h5 class=\\\"elementor-heading-title elementor-size-default\\\">A\\\/Prof Chu Jang Hann<\\\/h5>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-6b57969 elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\\\" data-id=\\\"6b57969\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"icon-list.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t<ul class=\\\"elementor-icon-list-items elementor-inline-items\\\">\\n\\t\\t\\t\\t\\t\\t\\t<li class=\\\"elementor-icon-list-item elementor-inline-item\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<a href=\\\"mailto:miccjh@nus.edu.sg\\\">\\n\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<span class=\\\"elementor-icon-list-icon\\\">\\n\\t\\t\\t\\t\\t\\t\\t<svg aria-hidden=\\\"true\\\" class=\\\"e-font-icon-svg e-fas-envelope\\\" viewBox=\\\"0 0 512 512\\\" xmlns=\\\"http:\\\/\\\/www.w3.org\\\/2000\\\/svg\\\"><path d=\\\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\\\"><\\\/path><\\\/svg>\\t\\t\\t\\t\\t\\t<\\\/span>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<span class=\\\"elementor-icon-list-text\\\">miccjh@nus.edu.sg<\\\/span>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/a>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/li>\\n\\t\\t\\t\\t\\t\\t<\\\/ul>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-dc37993 elementor-widget elementor-widget-heading\\\" data-id=\\\"dc37993\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h6 class=\\\"elementor-heading-title elementor-size-default\\\">Department of Microbiology & Immunology\\u00a0\\n<\\\/h6>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/section>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/section>\\n\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\"}},{\"@type\":\"Question\",\"name\":\"Elucidating capsular polysaccharide biogenesis in Streptococcus pneumoniae\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"\\t\\t<div data-elementor-type=\\\"section\\\" data-elementor-id=\\\"3997\\\" class=\\\"elementor elementor-3997\\\" data-elementor-post-type=\\\"elementor_library\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<section class=\\\"elementor-section elementor-top-section elementor-element elementor-element-1d1afdc elementor-section-boxed elementor-section-height-default elementor-section-height-default\\\" data-id=\\\"1d1afdc\\\" data-element_type=\\\"section\\\">\\n\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-container elementor-column-gap-default\\\">\\n\\t\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-55745f2\\\" data-id=\\\"55745f2\\\" data-element_type=\\\"column\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-07d6ba9 elementor-widget elementor-widget-text-editor\\\" data-id=\\\"07d6ba9\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"text-editor.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t\\t\\t<p>Streptococcus pneumoniae is an important respiratory pathogen that causes more than one million deaths worldwide annually. Similar to other pathogenic bacteria, S. pneumoniae encases its cell envelope with capsular polysaccharide (CPS). This layer protects the cell from host insults, such as opsonophagocytosis and mucus clearance. Because of its importance in pathogenesis, all clinically relevant vaccines against S. pneumoniae target the CPS. There are at least 100 serotypes identified and the structural variation of CPS is attributed to the extreme diversity of glycosyltransferases (GTs), flippases, and polymerases at the cps locus. Little is known about the molecular mechanisms governing their specificity, regulation, and function. The long-term goal of this project is to\\u00a0investigate the specificity determinants of CPS enzymes based on the wealth of structural information available for\\u00a0pneumococcal CPS. Our approach is enabled by conditional essentiality of the CPS enzymes and the genetic tractability of S. pneumoniae.\\u00a0<\\\/p><p>Understanding how CPSs are synthesized in S. pneumoniae is critical to improve our current antimicrobial and vaccine strategies. Enzyme variants isolated from this work will be valuable tools for synthetic biology and glycoengineering. Besides studying CPS enzymes, we are interested in finding small molecules that inhibit different steps of the CPS pathway as therapeutics.<\\\/p>\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<section class=\\\"elementor-section elementor-inner-section elementor-element elementor-element-d5a48b0 elementor-section-boxed elementor-section-height-default elementor-section-height-default\\\" data-id=\\\"d5a48b0\\\" data-element_type=\\\"section\\\">\\n\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-container elementor-column-gap-default\\\">\\n\\t\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-52c0950\\\" data-id=\\\"52c0950\\\" data-element_type=\\\"column\\\" data-settings=\\\"{"background_background":"classic"}\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-00ce2f0 elementor-widget__width-initial elementor-widget elementor-widget-image\\\" data-id=\\\"00ce2f0\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"image.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<img width=\\\"193\\\" height=\\\"174\\\" src=\\\"https:\\\/\\\/medicine.nus.edu.sg\\\/trp\\\/infectious-diseases\\\/wp-content\\\/uploads\\\/sites\\\/7\\\/2022\\\/01\\\/aeroplane.svg\\\" class=\\\"attachment-full size-full wp-image-2645\\\" alt=\\\"\\\" loading=\\\"lazy\\\" \\\/>\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-924feb8 elementor-widget__width-initial elementor-widget elementor-widget-heading\\\" data-id=\\\"924feb8\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h4 class=\\\"elementor-heading-title elementor-size-default\\\">All applications<br>\\nto send to: <\\\/h4>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-b89e005\\\" data-id=\\\"b89e005\\\" data-element_type=\\\"column\\\" data-settings=\\\"{"background_background":"classic"}\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-3b7a0e8 elementor-widget elementor-widget-heading\\\" data-id=\\\"3b7a0e8\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h5 class=\\\"elementor-heading-title elementor-size-default\\\">Dr Sham Lok To, Chris <\\\/h5>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-b13e2f3 elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\\\" data-id=\\\"b13e2f3\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"icon-list.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t<ul class=\\\"elementor-icon-list-items elementor-inline-items\\\">\\n\\t\\t\\t\\t\\t\\t\\t<li class=\\\"elementor-icon-list-item elementor-inline-item\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<a href=\\\"mailto:miclts@nus.edu.sg\\\">\\n\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<span class=\\\"elementor-icon-list-icon\\\">\\n\\t\\t\\t\\t\\t\\t\\t<svg aria-hidden=\\\"true\\\" class=\\\"e-font-icon-svg e-fas-envelope\\\" viewBox=\\\"0 0 512 512\\\" xmlns=\\\"http:\\\/\\\/www.w3.org\\\/2000\\\/svg\\\"><path d=\\\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\\\"><\\\/path><\\\/svg>\\t\\t\\t\\t\\t\\t<\\\/span>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<span class=\\\"elementor-icon-list-text\\\">miclts@nus.edu.sg<\\\/span>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/a>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/li>\\n\\t\\t\\t\\t\\t\\t<\\\/ul>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-86343a8 elementor-widget elementor-widget-heading\\\" data-id=\\\"86343a8\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h6 class=\\\"elementor-heading-title elementor-size-default\\\">Department of Microbiology & Immunology\\u00a0\\n<\\\/h6>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/section>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/section>\\n\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\"}},{\"@type\":\"Question\",\"name\":\"Applying single cell genomics to gain new insights into recurrent urinary tract infection, potentially leading to novel treatment strategies\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"\\t\\t<div data-elementor-type=\\\"section\\\" data-elementor-id=\\\"4003\\\" class=\\\"elementor elementor-4003\\\" data-elementor-post-type=\\\"elementor_library\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<section class=\\\"elementor-section elementor-top-section elementor-element elementor-element-89f3a73 elementor-section-boxed elementor-section-height-default elementor-section-height-default\\\" data-id=\\\"89f3a73\\\" data-element_type=\\\"section\\\">\\n\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-container elementor-column-gap-default\\\">\\n\\t\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-98285bb\\\" data-id=\\\"98285bb\\\" data-element_type=\\\"column\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-e8ad9ff elementor-widget elementor-widget-text-editor\\\" data-id=\\\"e8ad9ff\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"text-editor.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t\\t\\t<p>Urinary tract infections (UTIs) are among the most common infections of humans and a major reason why people take antibiotics. This, in turn, leads to higher antibiotic resistance rates. The primary clinical problem in treating UTI is that for some patients, UTIs recur frequently, despite sometimes prolonged courses of antibiotic therapy. While the majority of bacteria during a UTI are extracellular and present in the urine in the lumen of the bladder (which makes them easy to isolate, monitor, and treat), a subset of intracellular bacteria within the bladder epithelial cells is relatively resistant to antibiotic treatment and host immune defenses. These intracellular bacteria can therefore persist for weeks to months in the bladder (presumably causing no symptoms); upon reactivation, they can cause recurrent UTI. We are applying advances in single cell genomics to understand how UPEC are able to enter and survive in the intracellular niche. Some of our genetic and protein engineering tools are crucial for this work, enabling us to manipulate and visualize clinical strains of UPEC<\\\/p>\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<section class=\\\"elementor-section elementor-inner-section elementor-element elementor-element-9f442bd elementor-section-boxed elementor-section-height-default elementor-section-height-default\\\" data-id=\\\"9f442bd\\\" data-element_type=\\\"section\\\">\\n\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-container elementor-column-gap-default\\\">\\n\\t\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-d320494\\\" data-id=\\\"d320494\\\" data-element_type=\\\"column\\\" data-settings=\\\"{"background_background":"classic"}\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-2739b8d elementor-widget__width-initial elementor-widget elementor-widget-image\\\" data-id=\\\"2739b8d\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"image.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<img width=\\\"193\\\" height=\\\"174\\\" src=\\\"https:\\\/\\\/medicine.nus.edu.sg\\\/trp\\\/infectious-diseases\\\/wp-content\\\/uploads\\\/sites\\\/7\\\/2022\\\/01\\\/aeroplane.svg\\\" class=\\\"attachment-full size-full wp-image-2645\\\" alt=\\\"\\\" loading=\\\"lazy\\\" \\\/>\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-88cce0f elementor-widget__width-initial elementor-widget elementor-widget-heading\\\" data-id=\\\"88cce0f\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h4 class=\\\"elementor-heading-title elementor-size-default\\\">All applications<br>\\nto send to: <\\\/h4>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-3de4b92\\\" data-id=\\\"3de4b92\\\" data-element_type=\\\"column\\\" data-settings=\\\"{"background_background":"classic"}\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-8233986 elementor-widget elementor-widget-heading\\\" data-id=\\\"8233986\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h5 class=\\\"elementor-heading-title elementor-size-default\\\">A\\\/Prof Swaine Chen\\u00a0<\\\/h5>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-a0f8003 elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\\\" data-id=\\\"a0f8003\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"icon-list.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t<ul class=\\\"elementor-icon-list-items elementor-inline-items\\\">\\n\\t\\t\\t\\t\\t\\t\\t<li class=\\\"elementor-icon-list-item elementor-inline-item\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<a href=\\\"mailto:mdcslc@nus.edu.sg\\\">\\n\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<span class=\\\"elementor-icon-list-icon\\\">\\n\\t\\t\\t\\t\\t\\t\\t<svg aria-hidden=\\\"true\\\" class=\\\"e-font-icon-svg e-fas-envelope\\\" viewBox=\\\"0 0 512 512\\\" xmlns=\\\"http:\\\/\\\/www.w3.org\\\/2000\\\/svg\\\"><path d=\\\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\\\"><\\\/path><\\\/svg>\\t\\t\\t\\t\\t\\t<\\\/span>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<span class=\\\"elementor-icon-list-text\\\">mdcslc@nus.edu.sg<\\\/span>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/a>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/li>\\n\\t\\t\\t\\t\\t\\t<\\\/ul>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-d650ebe elementor-widget elementor-widget-heading\\\" data-id=\\\"d650ebe\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h6 class=\\\"elementor-heading-title elementor-size-default\\\">Department of Medicine\\u00a0<\\\/h6>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/section>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/section>\\n\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\"}},{\"@type\":\"Question\",\"name\":\"Developing sexual genetics in E. coli as a new, complimentary engine for synthetic biology applications\\u00a0\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"\\t\\t<div data-elementor-type=\\\"section\\\" data-elementor-id=\\\"4007\\\" class=\\\"elementor elementor-4007\\\" data-elementor-post-type=\\\"elementor_library\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<section class=\\\"elementor-section elementor-top-section elementor-element elementor-element-8750d38 elementor-section-boxed elementor-section-height-default elementor-section-height-default\\\" data-id=\\\"8750d38\\\" data-element_type=\\\"section\\\">\\n\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-container elementor-column-gap-default\\\">\\n\\t\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-d3e0bb3\\\" data-id=\\\"d3e0bb3\\\" data-element_type=\\\"column\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-b97b51d elementor-widget elementor-widget-text-editor\\\" data-id=\\\"b97b51d\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"text-editor.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t\\t\\t<p>Genetics has been a cornerstone of biological discovery, leading to understanding, diagnosis, and treatments for numerous human diseases. The history of genetics traces its roots to Gregor Mendel\\u2019s iconic experiments hybridizing pea plants; a direct line to powerful genetic systems in Drosophila and mice has enabled breakthroughs ranging from congenital disease to cancer.\\u00a0<\\\/p><p>The Chen lab has developed several genetic techniques, in particular focusing on general tools that can be used in wild-type strains of E. coli in addition to the \\u201ceasier\\u201d lab-adapted strains traditionally used for synthetic biology. These tools now, for the first time, enable access to the power of sexual genetics (like that which powers mouse or human genetic studies) combined with high throughput genomics in Escherichia coli, the most well studied bacterium and most important chassis organism for synthetic biology. The marriage of sexual genetics with E. coli enables unprecedented opportunities for research discovery (which requires a robust resource supply chain) and for developing and marketing boutique, purpose-built custom chassis for the broader biotechnology industry.<\\\/p>\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<section class=\\\"elementor-section elementor-inner-section elementor-element elementor-element-c8845d4 elementor-section-boxed elementor-section-height-default elementor-section-height-default\\\" data-id=\\\"c8845d4\\\" data-element_type=\\\"section\\\">\\n\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-container elementor-column-gap-default\\\">\\n\\t\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-2dddfab\\\" data-id=\\\"2dddfab\\\" data-element_type=\\\"column\\\" data-settings=\\\"{"background_background":"classic"}\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-8bc330d elementor-widget__width-initial elementor-widget elementor-widget-image\\\" data-id=\\\"8bc330d\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"image.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<img width=\\\"193\\\" height=\\\"174\\\" src=\\\"https:\\\/\\\/medicine.nus.edu.sg\\\/trp\\\/infectious-diseases\\\/wp-content\\\/uploads\\\/sites\\\/7\\\/2022\\\/01\\\/aeroplane.svg\\\" class=\\\"attachment-full size-full wp-image-2645\\\" alt=\\\"\\\" loading=\\\"lazy\\\" \\\/>\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-a06e860 elementor-widget__width-initial elementor-widget elementor-widget-heading\\\" data-id=\\\"a06e860\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h4 class=\\\"elementor-heading-title elementor-size-default\\\">All applications<br>\\nto send to: <\\\/h4>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-5e6b42e\\\" data-id=\\\"5e6b42e\\\" data-element_type=\\\"column\\\" data-settings=\\\"{"background_background":"classic"}\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-2cad91a elementor-widget elementor-widget-heading\\\" data-id=\\\"2cad91a\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h5 class=\\\"elementor-heading-title elementor-size-default\\\">A\\\/Prof Swaine Chen\\u00a0\\n<\\\/h5>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-625a5a2 elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\\\" data-id=\\\"625a5a2\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"icon-list.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t<ul class=\\\"elementor-icon-list-items elementor-inline-items\\\">\\n\\t\\t\\t\\t\\t\\t\\t<li class=\\\"elementor-icon-list-item elementor-inline-item\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<a href=\\\"mailto:mdcslc@nus.edu.sg\\\">\\n\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<span class=\\\"elementor-icon-list-icon\\\">\\n\\t\\t\\t\\t\\t\\t\\t<svg aria-hidden=\\\"true\\\" class=\\\"e-font-icon-svg e-fas-envelope\\\" viewBox=\\\"0 0 512 512\\\" xmlns=\\\"http:\\\/\\\/www.w3.org\\\/2000\\\/svg\\\"><path d=\\\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\\\"><\\\/path><\\\/svg>\\t\\t\\t\\t\\t\\t<\\\/span>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<span class=\\\"elementor-icon-list-text\\\">mdcslc@nus.edu.sg<\\\/span>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/a>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/li>\\n\\t\\t\\t\\t\\t\\t<\\\/ul>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-563a843 elementor-widget elementor-widget-heading\\\" data-id=\\\"563a843\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h6 class=\\\"elementor-heading-title elementor-size-default\\\">Department of Medicine<\\\/h6>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/section>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/section>\\n\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\"}},{\"@type\":\"Question\",\"name\":\"Explaining the 2015 GBS yu sheng outbreak in Singapore - and ongoing GBS infections\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"\\t\\t<div data-elementor-type=\\\"section\\\" data-elementor-id=\\\"4013\\\" class=\\\"elementor elementor-4013\\\" data-elementor-post-type=\\\"elementor_library\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<section class=\\\"elementor-section elementor-top-section elementor-element elementor-element-594d497 elementor-section-boxed elementor-section-height-default elementor-section-height-default\\\" data-id=\\\"594d497\\\" data-element_type=\\\"section\\\">\\n\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-container elementor-column-gap-default\\\">\\n\\t\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-10b75dd\\\" data-id=\\\"10b75dd\\\" data-element_type=\\\"column\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-a9d5fbc elementor-widget elementor-widget-text-editor\\\" data-id=\\\"a9d5fbc\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"text-editor.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t\\t\\t<p>The largest reported outbreak of group B Streptococcus (GBS) infections occurred in Singapore in 2015, involving over 300 cases of bloodstream infections. This outbreak was associated with consumption of \\u9b5a\\u751f (yu sheng), a dish made from sliced raw fish and served with rice porridge by food stalls. Such foodborne transmission leading to invasive disease had not been reported prior to this outbreak. One clone of GBS, referred to as ST283, was responsible for this outbreak; this strain is almost exclusively found in Southeast Asia in both humans and fish. This project uses genomics, genetics, microbiology, and an animal model of infection to discover why ST283 GBS is so proficient at causing disease in humans and why it is well adapted to aquaculture.\\u00a0<\\\/p>\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<section class=\\\"elementor-section elementor-inner-section elementor-element elementor-element-6a38aba elementor-section-boxed elementor-section-height-default elementor-section-height-default\\\" data-id=\\\"6a38aba\\\" data-element_type=\\\"section\\\">\\n\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-container elementor-column-gap-default\\\">\\n\\t\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-ba839cf\\\" data-id=\\\"ba839cf\\\" data-element_type=\\\"column\\\" data-settings=\\\"{"background_background":"classic"}\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-4d60593 elementor-widget__width-initial elementor-widget elementor-widget-image\\\" data-id=\\\"4d60593\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"image.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<img width=\\\"193\\\" height=\\\"174\\\" src=\\\"https:\\\/\\\/medicine.nus.edu.sg\\\/trp\\\/infectious-diseases\\\/wp-content\\\/uploads\\\/sites\\\/7\\\/2022\\\/01\\\/aeroplane.svg\\\" class=\\\"attachment-full size-full wp-image-2645\\\" alt=\\\"\\\" loading=\\\"lazy\\\" \\\/>\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-be5c549 elementor-widget__width-initial elementor-widget elementor-widget-heading\\\" data-id=\\\"be5c549\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h4 class=\\\"elementor-heading-title elementor-size-default\\\">All applications<br>\\nto send to: <\\\/h4>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-c800547\\\" data-id=\\\"c800547\\\" data-element_type=\\\"column\\\" data-settings=\\\"{"background_background":"classic"}\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-853e85e elementor-widget elementor-widget-heading\\\" data-id=\\\"853e85e\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h5 class=\\\"elementor-heading-title elementor-size-default\\\">A\\\/Prof Swaine Chen\\u00a0\\n<\\\/h5>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-6d56b24 elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\\\" data-id=\\\"6d56b24\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"icon-list.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t<ul class=\\\"elementor-icon-list-items elementor-inline-items\\\">\\n\\t\\t\\t\\t\\t\\t\\t<li class=\\\"elementor-icon-list-item elementor-inline-item\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<a href=\\\"mailto:mdcslc@nus.edu.sg\\\">\\n\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<span class=\\\"elementor-icon-list-icon\\\">\\n\\t\\t\\t\\t\\t\\t\\t<svg aria-hidden=\\\"true\\\" class=\\\"e-font-icon-svg e-fas-envelope\\\" viewBox=\\\"0 0 512 512\\\" xmlns=\\\"http:\\\/\\\/www.w3.org\\\/2000\\\/svg\\\"><path d=\\\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\\\"><\\\/path><\\\/svg>\\t\\t\\t\\t\\t\\t<\\\/span>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<span class=\\\"elementor-icon-list-text\\\">mdcslc@nus.edu.sg<\\\/span>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/a>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/li>\\n\\t\\t\\t\\t\\t\\t<\\\/ul>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-9c250ce elementor-widget elementor-widget-heading\\\" data-id=\\\"9c250ce\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h6 class=\\\"elementor-heading-title elementor-size-default\\\">Department of Medicine\\u00a0<\\\/h6>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/section>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/section>\\n\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\"}},{\"@type\":\"Question\",\"name\":\"Studying viral-host interactions in chronic hepatitis viral infection versus acute viral infection by newly emerged viruses\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"\\t\\t<div data-elementor-type=\\\"section\\\" data-elementor-id=\\\"4023\\\" class=\\\"elementor elementor-4023\\\" data-elementor-post-type=\\\"elementor_library\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<section class=\\\"elementor-section elementor-top-section elementor-element elementor-element-ba03a49 elementor-section-boxed elementor-section-height-default elementor-section-height-default\\\" data-id=\\\"ba03a49\\\" data-element_type=\\\"section\\\">\\n\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-container elementor-column-gap-default\\\">\\n\\t\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-80967d0\\\" data-id=\\\"80967d0\\\" data-element_type=\\\"column\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-c752a3f elementor-widget elementor-widget-text-editor\\\" data-id=\\\"c752a3f\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"text-editor.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t\\t\\t<p>Approximately 2 billion people have been infected by two viruses, hepatitis B virus (HBV) and hepatitis C virus (HCV), which primarily attack the liver. Although HCV and HBV are completely different viruses, both of them preferentially infect hepatocytes and are able to subvert the innate and adaptive immunity, leading to chronic infection. In contrast, acute infection happens for many newly emerged viruses, like influenza A virus and coronavirus, after zoonotic transmission. For all these viruses, the complex interplay between viral proteins and host cell machineries contributes to viral replication and\\\/or pathogenesis. However, the exact manner by which each virus participates in this complex process is not completely understood. In this project, we will use a multidisciplinary approach to identify host factors that are regulated by different viral proteins. The functional significance of novel viral-host interactions identified will be analyzed by using cell culture systems. Identification of novel viral-host interaction therefore offers opportunities for designing new treatments and prevention strategies.\\u00a0<\\\/p>\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<section class=\\\"elementor-section elementor-inner-section elementor-element elementor-element-a7de9bc elementor-section-boxed elementor-section-height-default elementor-section-height-default\\\" data-id=\\\"a7de9bc\\\" data-element_type=\\\"section\\\">\\n\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-container elementor-column-gap-default\\\">\\n\\t\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-89bb4fd\\\" data-id=\\\"89bb4fd\\\" data-element_type=\\\"column\\\" data-settings=\\\"{"background_background":"classic"}\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-bf5d8b2 elementor-widget__width-initial elementor-widget elementor-widget-image\\\" data-id=\\\"bf5d8b2\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"image.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<img width=\\\"193\\\" height=\\\"174\\\" src=\\\"https:\\\/\\\/medicine.nus.edu.sg\\\/trp\\\/infectious-diseases\\\/wp-content\\\/uploads\\\/sites\\\/7\\\/2022\\\/01\\\/aeroplane.svg\\\" class=\\\"attachment-full size-full wp-image-2645\\\" alt=\\\"\\\" loading=\\\"lazy\\\" \\\/>\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-15068a4 elementor-widget__width-initial elementor-widget elementor-widget-heading\\\" data-id=\\\"15068a4\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h4 class=\\\"elementor-heading-title elementor-size-default\\\">All applications<br>\\nto send to: <\\\/h4>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-661c8b9\\\" data-id=\\\"661c8b9\\\" data-element_type=\\\"column\\\" data-settings=\\\"{"background_background":"classic"}\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-8aa3b1f elementor-widget elementor-widget-heading\\\" data-id=\\\"8aa3b1f\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h5 class=\\\"elementor-heading-title elementor-size-default\\\">A\\\/Prof Tan Yee Joo\\u00a0\\n<\\\/h5>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-1001a9f elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\\\" data-id=\\\"1001a9f\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"icon-list.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t<ul class=\\\"elementor-icon-list-items elementor-inline-items\\\">\\n\\t\\t\\t\\t\\t\\t\\t<li class=\\\"elementor-icon-list-item elementor-inline-item\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<a href=\\\"mailto:mictyj@nus.edu.sg\\\">\\n\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<span class=\\\"elementor-icon-list-icon\\\">\\n\\t\\t\\t\\t\\t\\t\\t<svg aria-hidden=\\\"true\\\" class=\\\"e-font-icon-svg e-fas-envelope\\\" viewBox=\\\"0 0 512 512\\\" xmlns=\\\"http:\\\/\\\/www.w3.org\\\/2000\\\/svg\\\"><path d=\\\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\\\"><\\\/path><\\\/svg>\\t\\t\\t\\t\\t\\t<\\\/span>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<span class=\\\"elementor-icon-list-text\\\">mictyj@nus.edu.sg<\\\/span>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/a>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/li>\\n\\t\\t\\t\\t\\t\\t<\\\/ul>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-65b05bf elementor-widget elementor-widget-heading\\\" data-id=\\\"65b05bf\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h6 class=\\\"elementor-heading-title elementor-size-default\\\">Department of Microbiology & Immunology\\u00a0\\n<\\\/h6>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/section>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/section>\\n\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\"}},{\"@type\":\"Question\",\"name\":\"Achieving Functional Cure of Chronic Hepatitis B\",\"acceptedAnswer\":{\"@type\":\"Answer\",\"text\":\"<div class=\\\"page\\\" title=\\\"Page 20\\\"><div class=\\\"section\\\"><div class=\\\"layoutArea\\\"><div class=\\\"column\\\"><p style=\\\"text-align: justify;\\\">\\t\\t<div data-elementor-type=\\\"page\\\" data-elementor-id=\\\"5473\\\" class=\\\"elementor elementor-5473\\\" data-elementor-post-type=\\\"elementor_library\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t<section class=\\\"elementor-section elementor-top-section elementor-element elementor-element-ba03a49 elementor-section-boxed elementor-section-height-default elementor-section-height-default\\\" data-id=\\\"ba03a49\\\" data-element_type=\\\"section\\\">\\n\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-container elementor-column-gap-default\\\">\\n\\t\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-80967d0\\\" data-id=\\\"80967d0\\\" data-element_type=\\\"column\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-c752a3f elementor-widget elementor-widget-text-editor\\\" data-id=\\\"c752a3f\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"text-editor.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t\\t\\t<p style=\\\"caret-color: #000000; color: #000000; text-align: justify;\\\">Chronic Hepatitis B is chronic viral disease affecting the liver and there are over 270million infected patients globally, being the most common cause of liver disease and liver cancer globally. Functional cure (HBsAg loss) is an achievable goal leading to improved survival, lower liver cancer and liver complications.<\\\/p><div class=\\\"page\\\" style=\\\"caret-color: #000000; color: #000000;\\\" title=\\\"Page 21\\\"><div class=\\\"section\\\"><div class=\\\"layoutArea\\\"><div class=\\\"column\\\"><p style=\\\"text-align: justify;\\\">The biology of different stages of Chronic Hepatitis B (CHB) is still not well understood but insights are likely with deep multidimensional phenotyping comprising genomics, transcriptomics, proteomics , microRNA, immunology and virological characterisation, an opportunity we are well placed to explore with our well established cohort of over 2000 Chronic Hepatitis B patients The main focus will be on functional cure of CHB defined as HBsAg loss, not achievable with current therapies.<\\\/p><p style=\\\"text-align: justify;\\\">The objectives of our proposal is the understand the virological and immune mechanisms involved in functional cure by examining the liver microenvironment with state of the art technologies such as single cell analysis, genomics, transcriptomics, proteomics, and epigenetics in patients with\\\/without functional cure. As the key to CHB is an indepth analysis of epigenetics of cccDNA, factors found in the HBV TCR to be important in viral replication will be investigated to understand their direct or indirect relationship to HBV. Concurrently, a validated target for HBV will be a particular focus for assay development, computerised modelling, and medicinal library development as possible new classes of antiviral agents. New mechanisms of action, and new antiviral agents can be tested out in the humanised mouse model which is being developed as a model-of-choice for CHB with chronic HBV infected hepatocytes and a fully matched immune system.<\\\/p><p style=\\\"text-align: justify;\\\">Potential projects for suitable applicants, esp those interested in PhD projects<\\\/p><p style=\\\"text-align: justify;\\\">1. Transcriptome analysis of intrahepatic versus peripheral blood compartment in CHB patients with and without functional cure<\\\/p><p style=\\\"text-align: justify;\\\">2. Functional immunological analysis of intrahepatic compared to peripheral blood in functional cure<\\\/p><p style=\\\"text-align: justify;\\\">3. Innate versus adaptive intrahepatic immune responses in CHB patients with and without functional cure<\\\/p><p style=\\\"text-align: justify;\\\">4. Examination of HBV minichrosome (cccDNA)quantity and function in CHB livers in patients with and without functional cure 5. Dissecting cccDNA silencing mechanisms in patients with and without functional cure of CHB<\\\/p><p style=\\\"text-align: justify;\\\">6. Assay development in novel targets towards HBV<\\\/p><p style=\\\"text-align: justify;\\\">7. Medicinal library construction of potential antiviral agents using novel targets and assays<\\\/p><p style=\\\"text-align: justify;\\\">8. Humanised mice models for Chronic hepatitis B<\\\/p><\\\/div><\\\/div><\\\/div><\\\/div>\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<section class=\\\"elementor-section elementor-inner-section elementor-element elementor-element-a7de9bc elementor-section-boxed elementor-section-height-default elementor-section-height-default\\\" data-id=\\\"a7de9bc\\\" data-element_type=\\\"section\\\">\\n\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-container elementor-column-gap-default\\\">\\n\\t\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-89bb4fd\\\" data-id=\\\"89bb4fd\\\" data-element_type=\\\"column\\\" data-settings=\\\"{"background_background":"classic"}\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-bf5d8b2 elementor-widget__width-initial elementor-widget elementor-widget-image\\\" data-id=\\\"bf5d8b2\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"image.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<img width=\\\"193\\\" height=\\\"174\\\" src=\\\"https:\\\/\\\/medicine.nus.edu.sg\\\/trp\\\/infectious-diseases\\\/wp-content\\\/uploads\\\/sites\\\/7\\\/2022\\\/01\\\/aeroplane.svg\\\" class=\\\"attachment-full size-full wp-image-2645\\\" alt=\\\"\\\" loading=\\\"lazy\\\" \\\/>\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-15068a4 elementor-widget__width-initial elementor-widget elementor-widget-heading\\\" data-id=\\\"15068a4\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h4 class=\\\"elementor-heading-title elementor-size-default\\\">All applications<br>\\nto send to: <\\\/h4>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-column elementor-col-50 elementor-inner-column elementor-element elementor-element-661c8b9\\\" data-id=\\\"661c8b9\\\" data-element_type=\\\"column\\\" data-settings=\\\"{"background_background":"classic"}\\\">\\n\\t\\t\\t<div class=\\\"elementor-widget-wrap elementor-element-populated\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-8aa3b1f elementor-widget elementor-widget-heading\\\" data-id=\\\"8aa3b1f\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h5 class=\\\"elementor-heading-title elementor-size-default\\\">A\\\/Prof Tan Yee Joo\\u00a0\\n<\\\/h5>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-1001a9f elementor-icon-list--layout-inline elementor-list-item-link-full_width elementor-widget elementor-widget-icon-list\\\" data-id=\\\"1001a9f\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"icon-list.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t\\t\\t<ul class=\\\"elementor-icon-list-items elementor-inline-items\\\">\\n\\t\\t\\t\\t\\t\\t\\t<li class=\\\"elementor-icon-list-item elementor-inline-item\\\">\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<a href=\\\"mailto:mictyj@nus.edu.sg\\\">\\n\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<span class=\\\"elementor-icon-list-icon\\\">\\n\\t\\t\\t\\t\\t\\t\\t<svg aria-hidden=\\\"true\\\" class=\\\"e-font-icon-svg e-fas-envelope\\\" viewBox=\\\"0 0 512 512\\\" xmlns=\\\"http:\\\/\\\/www.w3.org\\\/2000\\\/svg\\\"><path d=\\\"M502.3 190.8c3.9-3.1 9.7-.2 9.7 4.7V400c0 26.5-21.5 48-48 48H48c-26.5 0-48-21.5-48-48V195.6c0-5 5.7-7.8 9.7-4.7 22.4 17.4 52.1 39.5 154.1 113.6 21.1 15.4 56.7 47.8 92.2 47.6 35.7.3 72-32.8 92.3-47.6 102-74.1 131.6-96.3 154-113.7zM256 320c23.2.4 56.6-29.2 73.4-41.4 132.7-96.3 142.8-104.7 173.4-128.7 5.8-4.5 9.2-11.5 9.2-18.9v-19c0-26.5-21.5-48-48-48H48C21.5 64 0 85.5 0 112v19c0 7.4 3.4 14.3 9.2 18.9 30.6 23.9 40.7 32.4 173.4 128.7 16.8 12.2 50.2 41.8 73.4 41.4z\\\"><\\\/path><\\\/svg>\\t\\t\\t\\t\\t\\t<\\\/span>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<span class=\\\"elementor-icon-list-text\\\">mictyj@nus.edu.sg<\\\/span>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/a>\\n\\t\\t\\t\\t\\t\\t\\t\\t\\t<\\\/li>\\n\\t\\t\\t\\t\\t\\t<\\\/ul>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t<div class=\\\"elementor-element elementor-element-65b05bf elementor-widget elementor-widget-heading\\\" data-id=\\\"65b05bf\\\" data-element_type=\\\"widget\\\" data-widget_type=\\\"heading.default\\\">\\n\\t\\t\\t\\t<div class=\\\"elementor-widget-container\\\">\\n\\t\\t\\t<h6 class=\\\"elementor-heading-title elementor-size-default\\\">Department of Microbiology & Immunology\\u00a0\\n<\\\/h6>\\t\\t<\\\/div>\\n\\t\\t\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/section>\\n\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/div>\\n\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/section>\\n\\t\\t\\t\\t\\t\\t\\t<\\\/div>\\n\\t\\t<\\\/p><\\\/div><\\\/div><\\\/div><\\\/div>\"}}]}<\/script>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-ed425fb elementor-widget elementor-widget-text-editor\" data-id=\"ed425fb\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t\t\t\t\t<p>Graduate students are welcome to join the following available projects under ID TRP’s Researchers.\u00a0<\/p><p>Admission into the School’s Graduate Programme is based on guidelines established by the University. More details on the admission requirements can be found <a href=\"https:\/\/medicine.nus.edu.sg\/graduatestudies\/prospective-students\/graduate-admission\/admission-requirements\/\" target=\"_blank\" rel=\"noopener\">here<\/a>.<\/p><p>More information regarding the Graduate\u00a0Programme is available at:\u00a0<a href=\"https:\/\/medicine.nus.edu.sg\/graduatestudies\/prospective-students\/graduate-programme\/\" target=\"_blank\" rel=\"noopener\">Graduate Education at NUS Medicine<\/a>.<\/p><p>Please take note of the application deadlines.There are two intakes per academic year, one in August and the other in January. All copies of the applications must reach the Dean\u2019s office by 15 November (of the previous year) for the August intake, and by 15 May (of the previous year) for the January intake.<\/p><p>Please submit your application and supporting documents online at:\u00a0<a href=\"https:\/\/inetapps.nus.edu.sg\/GDA2\/Home.aspx\" target=\"_blank\" rel=\"noopener\">Graduate Admission System<\/a><\/p>\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>CareerJoin our dynamic team Faculty Position Research Position Graduate Students Faculty Position Assistant Professor, Associate Professor or Full Professor\u200b \u200b The Infectious Diseases Translational Research Programme (ID TRP), Yong Loo Lin School of Medicine, National University of Singapore (NUS), invites applications for two tenure track faculty positions at Assistant Professor, Associate Professor or Full Professor […]<\/p>\n","protected":false},"author":11,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"elementor_header_footer","meta":{"footnotes":""},"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v21.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Careers - Infectious Diseases Translational Research Programme<\/title>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Careers - Infectious Diseases Translational Research Programme\" \/>\n<meta property=\"og:description\" content=\"CareerJoin our dynamic team Faculty Position Research Position Graduate Students Faculty Position Assistant Professor, Associate Professor or Full Professor\u200b \u200b The Infectious Diseases Translational Research Programme (ID TRP), Yong Loo Lin School of Medicine, National University of Singapore (NUS), invites applications for two tenure track faculty positions at Assistant Professor, Associate Professor or Full Professor […]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/careers\/\" \/>\n<meta property=\"og:site_name\" content=\"Infectious Diseases Translational Research Programme\" \/>\n<meta property=\"article:modified_time\" content=\"2024-08-21T05:03:44+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/medicine.nus.edu.sg\/trp\/wp-content\/uploads\/sites\/7\/2022\/01\/research-position.svg\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/careers\/\",\"url\":\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/careers\/\",\"name\":\"Careers - Infectious Diseases Translational Research Programme\",\"isPartOf\":{\"@id\":\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/#website\"},\"datePublished\":\"2021-11-06T04:08:24+00:00\",\"dateModified\":\"2024-08-21T05:03:44+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/careers\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/careers\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/careers\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Careers\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/#website\",\"url\":\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/\",\"name\":\"Infectious Diseases Translational Research Programme\",\"description\":\"Infectious Diseases Translational Research Programme\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Careers - Infectious Diseases Translational Research Programme","og_locale":"en_US","og_type":"article","og_title":"Careers - Infectious Diseases Translational Research Programme","og_description":"CareerJoin our dynamic team Faculty Position Research Position Graduate Students Faculty Position Assistant Professor, Associate Professor or Full Professor\u200b \u200b The Infectious Diseases Translational Research Programme (ID TRP), Yong Loo Lin School of Medicine, National University of Singapore (NUS), invites applications for two tenure track faculty positions at Assistant Professor, Associate Professor or Full Professor […]","og_url":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/careers\/","og_site_name":"Infectious Diseases Translational Research Programme","article_modified_time":"2024-08-21T05:03:44+00:00","og_image":[{"url":"https:\/\/medicine.nus.edu.sg\/trp\/wp-content\/uploads\/sites\/7\/2022\/01\/research-position.svg"}],"twitter_card":"summary_large_image","schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/careers\/","url":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/careers\/","name":"Careers - Infectious Diseases Translational Research Programme","isPartOf":{"@id":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/#website"},"datePublished":"2021-11-06T04:08:24+00:00","dateModified":"2024-08-21T05:03:44+00:00","breadcrumb":{"@id":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/careers\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/careers\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/careers\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/"},{"@type":"ListItem","position":2,"name":"Careers"}]},{"@type":"WebSite","@id":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/#website","url":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/","name":"Infectious Diseases Translational Research Programme","description":"Infectious Diseases Translational Research Programme","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"}]}},"_links":{"self":[{"href":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-json\/wp\/v2\/pages\/250"}],"collection":[{"href":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-json\/wp\/v2\/users\/11"}],"replies":[{"embeddable":true,"href":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-json\/wp\/v2\/comments?post=250"}],"version-history":[{"count":10,"href":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-json\/wp\/v2\/pages\/250\/revisions"}],"predecessor-version":[{"id":7196,"href":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-json\/wp\/v2\/pages\/250\/revisions\/7196"}],"wp:attachment":[{"href":"https:\/\/medicine.nus.edu.sg\/trp\/infectious-diseases\/wp-json\/wp\/v2\/media?parent=250"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}