Ion channels and transporters play essential roles in generating and maintaining electrical excitability of membranes found in neurons and muscle cells. The voltage-gated calcium channels support an equally critical role in Ca2+ signalling to initiate gene transcription or to activate Ca2+-dependant processes that have wider implications in cellular activities.

The speaker will share his group’s findings on the implications of post-transcriptional modifications of calcium channels such as alternative splicing and RNA editing on health and neurological disorders, as well as discuss the role nitrosylation of DMT1 transporter plays in neurodegenaration.

Speaker: Prof Soong Tuck Wah, Head, Department of Physiology