Manoor Prakash Hande

 

Manoor Prakash Hande

PhD (India): MPH (Singapore)

Associate Professor; Chair, Department Safety and Health Committee; Assistant Dean, Safety and Research Facilities Management (NUS Medicine)

+65-6516 3664 (Office); +65-6516 4928 (Lab)

+65-6778 8161

phsmph@nus.edu.sg

MD9, Department of Physiology, Level 4

MD9, Department of Physiology, Level 2

Genome Stability Laboratory

Research Areas of Interest:

  • Radiation Biology – biological response markers of exposure
  • Toxicogenomics and Environmental Toxicology
  • Telomeres and Telomerase in Ageing and Cancer
  • DNA damage response and repair

Selected Publications

  • Surniyantoro, H. N. E., Yusuf, D., Rahardjo, T., Rahajeng, N., Kisnanto, T., Nurhayati, S., Lusiyanti, Y., Syaifudin, M., & Hande, M. P. (2022). Assessment of hOGG1 Genetic Polymorphism (rs1052133) and DNA Damage in Radiation-Exposed Workers. Asian Pacific journal of cancer prevention : APJCP23(12), 4005–4012. https://doi.org/10.31557/APJCP.2022.23.12.4005
  • Srikanth, P, Chowdhury AR, Low GKM, Saraswathy R, Fujimori A, Banerjee B, Martinez-Lopez W, Hande MP 2022 Oxidative damage induced telomere mediated genomic instability in cells from Ataxia Telangiectasia patients. Genome Integrity. DOI: 10.14293/genint.13.1.003
  • Ng, G. Y., Hande, V., Ong, M. H., Wong, B. W., Loh, Z. W., Ho, W. D., Handison, L. B., Tan, I. M. P., Fann, D. Y., Arumugam, T. V., & Hande, M. P. (2022). Effects of dietary interventions on telomere dynamics. Mutation research. Genetic toxicology and environmental mutagenesis, 876-877, 503472. https://doi.org/10.1016/j.mrgentox.2022.503472
  • Chakraborty A, Roy S, Hande MP, Banerjee B 2021 Role of genomic instability and telomere attrition in unexplained recurrent pregnancy loss (Submitted).
  • Low GKM, Ting APL, Fok EDZ, Gopalakrishnan K, Zeegers, D, Khaw AK, Jayapal M, Martinez-Lopez W, Hande MP 2021 Role of xeroderma pigmentosum D (XPD) protein in genome maintenance in human cells under oxidative stress Mutation Research – Genetic Toxicology and Environmental Toxicology (Under Revision).
  • Hande V, Prathaban K, Hande MP 2021 Educational dialogue on public perception of nuclear radiation. International Journal of Radiation Biology (In press)
  • Hande V, Teo KYS, Wong JSM, Srikanth P, Sethu S, Martinez-Lopez W, Hande MP 2021 Investigations on the new mechanism of action for acetaldehyde-induced clastogenic effects in human lung fibroblasts. Mutation Research – Genetic Toxicology and Environmental Mutagenesis 861 -862: DOI: 10.1016/j.mrgentox.2020.503303
  • Chakraborty A, Pal I, Roy S, Koh SW, Hande MP, Banerjee B 2021 A novel de-novo balanced chromosomal translocation 19:22 along with 13ps+ n an azoospermic male: a case report. Journal of Reproduction & Infertility Vol 22 (2): 133 – 137. doi: 10.18502/jri.v22i2.5802.
  • Gregoire E, Barquinero JF, Gruel G, Benadjaoud M, Ainsbury E, Beinke C, Balajee A, , Beukes P, Blakely W, Dominguez I, Duy PN, Flegal FN, Gil OM, Güçlü I, Guogyte K, Hadjidekova V, Hadjidekova SP, Hande P, Jang S, Lumniczky K, Martinez JG, Meschini R, Milic M, Montoro A, Moreno M, Oestreicher U, Pajic J, Ricoul M, Sabatier L, Sebastia N, Sommer S, Szkarlat Z, Testa A, Terzoudi G, Valente M, Venkatachalam P, Vral A, Wilkins RC, Wojcik A, Zafiropoulos D, Kulka U. 2021 RENEB Inter-Laboratory Comparison 2017: limits and pitfalls of ILCs. International Journal of Radiation Biology 1-18 (DOI: 10.1080/09553002.2021.1928782)

Awards

  • Monbusho Scholarship

  • International Cancer Technology Transfer Fellowships (ICRETT) by the International Union Against Cancer (UICC-Union Internationale Contre le Cancer

  • Yamagiwa-Yoshida Memorial International Cancer Study Grant by the International Union Against Cancer (UICC-Union Internationale Contre le Cancer)

  • Outstanding Mentor Award, Science Mentorship Programme, Ministry of Education, Singapore

  • Outstanding Mentor Award, Science Mentorship Programme, Ministry of Education, Singapore

  • Editor-in-Chief, Genome Integrity - Wolters Kluwer

  • Consultant (cost free), Division of Human Health, International Atomic Energy Agency, Vienna, Austria

  • Member, Editorial Board, Mutation Research – Genetic Toxicology and Environmental Mutagenesis

  • Adjunct Professor, VIT University and Mangalore University, India

  • Expert Member, Workgroup on “Biological mechanisms influencing health effects from low-dose radiation exposure”, United Nations Scientific Committee on the Effects of Atomic Radiation (UNSCEAR), Vienna, Austria

  • Visiting Researcher, QST National Institute of Radiological Sciences, Chiba, Japan

  • Member, Committee 1 Radiation Effects, International Commission on Radiological Protection (ICRP), Canada

  • Associate Editor, International Journal of Radiation Biology

  • Panelist, Cross-Border Careers Scholar in Training Workshop, 68th Radiation Research Society Meeting, Hawaii, USA

  • Moderator/Co-Chair, S29 Transgenerational Effect Symposium, 68th Radiation Research Society Meeting, Hawaii, USA

  • Senior Advisor to training course and lecturer, International Advanced Training Course on Stakeholder Engagement for Recovery after Nuclear Disasters, Fukushima, Japan

  • Co-chair for the International Commission of Radiological Protection Task Group 121: Effects of Ionising Radiation Exposure in Offspring and Next Generations

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