{"id":985,"date":"2017-07-13T03:41:09","date_gmt":"2017-07-13T03:41:09","guid":{"rendered":"https:\/\/medicine.nus.edu.sg\/pcm\/?p=985"},"modified":"2017-07-13T03:41:09","modified_gmt":"2017-07-13T03:41:09","slug":"journal-club-frailty-among-older-singaporeans-singapore-longitudinal-ageing-study-and-frailty-intervention-trial","status":"publish","type":"post","link":"https:\/\/medicine.nus.edu.sg\/pcm\/journal-club-frailty-among-older-singaporeans-singapore-longitudinal-ageing-study-and-frailty-intervention-trial\/","title":{"rendered":"Journal Club \u2013 Frailty among Older Singaporeans: Singapore Longitudinal Ageing Study and Frailty Intervention Trial"},"content":{"rendered":"
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Date:<\/strong> 13 July 2017<\/p>\n

Time:<\/strong> 8-9AM<\/p>\n

Venue:<\/strong> Seminar Room T09- 04, Level 9, NUHS Tower Block<\/p>\n

Speaker:\u00a0<\/strong>A\/Prof Ng Tze Pin, Professorial Fellow, Dept. of Psychological Medicine, NUH<\/p>\n

Chairperson:<\/strong>\u00a0 Prof Kua Ee Heok, Senior Consultant, Dept. of Psychological Medicine, NUH<\/p>\n

Brief Abstract: <\/strong><\/p>\n

Using data from the Singapore Longitudinal Ageing Studies (SLAS) and the Frailty Intervention Trial, this presentation will summarize and discuss the prevalence of frailty, its healthcare and societal impact, its social and biomedical risk factors and correlates, in particular with cognitive impairment and depression, and blood biomarkers of dysregulated homeostatic pathways, in particular steroid hormone and insulin signalling-related anabolic pathways and energy metabolism, and immune cell and inflammation homeostasis.<\/p>\n

Importantly, physical frailty is reversible, and the effectiveness of nutritional, physical and cognitive training interventions has been demonstrated in a recent randomized controlled trial of pre-frail and frail older persons in the Singapore Frailty Intervention Trial (FIT).<\/p>\n

These findings herald an upcoming surge in translational research and implementation projects to screen, prevent and treat frailty in community and clinic settings to prevent or delay functional decline and institutional care, falls and hospitalization, and premature mortality in Singapore\u2019s ageing population.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Date: 13 July 2017 Time: 8-9AM Venue: Seminar Room T09- 04, Level 9, NUHS Tower Block Speaker:\u00a0A\/Prof Ng Tze Pin,…<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[10],"tags":[],"class_list":["post-985","post","type-post","status-publish","format-standard","hentry","category-events"],"acf":[],"yoast_head":"\nJournal Club \u2013 Frailty among Older Singaporeans: Singapore Longitudinal Ageing Study and Frailty Intervention Trial - NUS Dept of Psychological Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medicine.nus.edu.sg\/pcm\/journal-club-frailty-among-older-singaporeans-singapore-longitudinal-ageing-study-and-frailty-intervention-trial\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Journal Club \u2013 Frailty among Older Singaporeans: Singapore Longitudinal Ageing Study and Frailty Intervention Trial - 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