{"id":1009,"date":"2017-05-18T03:49:20","date_gmt":"2017-05-18T03:49:20","guid":{"rendered":"https:\/\/medicine.nus.edu.sg\/pcm\/?p=1009"},"modified":"2017-05-18T03:49:20","modified_gmt":"2017-05-18T03:49:20","slug":"journal-club-36-holes-in-the-roof-the-protocol-for-reversing-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/medicine.nus.edu.sg\/pcm\/journal-club-36-holes-in-the-roof-the-protocol-for-reversing-alzheimers-disease\/","title":{"rendered":"Journal Club \u2013 36 Holes in the Roof \u2013 The Protocol for Reversing Alzheimer\u2019s Disease"},"content":{"rendered":"<div class=\"fl-post-content clearfix\">\n<div class=\"fl-builder-content fl-builder-content-2101 fl-builder-content-primary fl-builder-global-templates-locked\" data-post-id=\"2101\">\n<div class=\"fl-row fl-row-fixed-width fl-row-bg-none fl-node-59926fdbcd6b9\" data-node=\"59926fdbcd6b9\">\n<div class=\"fl-row-content-wrap\">\n<div class=\"fl-row-content fl-row-fixed-width fl-node-content\">\n<div class=\"fl-col-group fl-node-59926fdbcd6fd\" data-node=\"59926fdbcd6fd\">\n<div class=\"fl-col fl-node-59926fdbcd73e\" data-node=\"59926fdbcd73e\">\n<div class=\"fl-col-content fl-node-content\">\n<div class=\"fl-module fl-module-rich-text fl-node-59926fdbcd77e\" data-node=\"59926fdbcd77e\">\n<div class=\"fl-module-content fl-node-content\">\n<div class=\"fl-rich-text\">\n<p><strong>Date:<\/strong> 18 May 2017<\/p>\n<p><strong>Time:<\/strong> 8-9AM<\/p>\n<p><strong>Venue:<\/strong> Seminar Room T09- 04, Level 9, NUHS Tower Block<\/p>\n<p><strong>Speaker:\u00a0<\/strong>Dr. Dale Bredesen, Founding President, Buck Institute for Research on Ageing; Professor, Department of Neurology, UCLA<\/p>\n<p><strong>Chairperson:<\/strong> \u00a0A\/Prof John Wong CM, Head &amp; Senior Consultant, Dept. of Psychological Medicine<\/p>\n<p><strong>Brief Abstract: <\/strong><\/p>\n<p>Cognitive decline is a major concern of the aging population. Already, Alzheimer\u2019s disease affects approximately 5.4 million Americans and 30 million people globally. Without effective prevention and treatment, the prospects for the future are bleak. The uniform failure of recent drug trials in Alzheimer\u2019s disease has highlighted the critical need for a more accurate understanding of the fundamental nature of Alzheimer\u2019s disease.<\/p>\n<p>Dr. Dale Bredesen\u2019s research has led to new insight that explains the erosion of memory seen in Alzheimer\u2019s disease, and has opened the door to a new therapeutic approach. He has found evidence that Alzheimer\u2019s disease stems from an imbalance in nerve cell signalling: in the normal brain, specific signals foster nerve connections and memory making, while balancing signals support memory breaking, allowing irrelevant information to be forgotten. The Bredesen Protocol has identified \u201836 holes\u2019 or mechanisms which have been developed into a comprehensive therapeutic programme that has in many cases helped Alzheimer\u2019s patients reverse their condition.<\/p>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>Date: 18 May 2017 Time: 8-9AM Venue: Seminar Room T09- 04, Level 9, NUHS Tower Block Speaker:\u00a0Dr. Dale Bredesen, Founding&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[10],"tags":[],"class_list":["post-1009","post","type-post","status-publish","format-standard","hentry","category-events"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.6 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Journal Club \u2013 36 Holes in the Roof \u2013 The Protocol for Reversing Alzheimer\u2019s Disease - NUS Dept of Psychological Medicine<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medicine.nus.edu.sg\/pcm\/journal-club-36-holes-in-the-roof-the-protocol-for-reversing-alzheimers-disease\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Journal Club \u2013 36 Holes in the Roof \u2013 The Protocol for Reversing Alzheimer\u2019s Disease - NUS Dept of Psychological Medicine\" \/>\n<meta property=\"og:description\" content=\"Date: 18 May 2017 Time: 8-9AM Venue: Seminar Room T09- 04, Level 9, NUHS Tower Block Speaker:\u00a0Dr. Dale Bredesen, Founding...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/medicine.nus.edu.sg\/pcm\/journal-club-36-holes-in-the-roof-the-protocol-for-reversing-alzheimers-disease\/\" \/>\n<meta property=\"og:site_name\" content=\"NUS Dept of Psychological Medicine\" \/>\n<meta property=\"article:published_time\" content=\"2017-05-18T03:49:20+00:00\" \/>\n<meta name=\"author\" content=\"Rupash\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"Rupash\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/medicine.nus.edu.sg\\\/pcm\\\/journal-club-36-holes-in-the-roof-the-protocol-for-reversing-alzheimers-disease\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/medicine.nus.edu.sg\\\/pcm\\\/journal-club-36-holes-in-the-roof-the-protocol-for-reversing-alzheimers-disease\\\/\"},\"author\":{\"name\":\"Rupash\",\"@id\":\"https:\\\/\\\/medicine.nus.edu.sg\\\/pcm\\\/#\\\/schema\\\/person\\\/0edf43c101a340f3d4313fa37951e8f6\"},\"headline\":\"Journal Club \u2013 36 Holes in the Roof \u2013 The Protocol for Reversing Alzheimer\u2019s Disease\",\"datePublished\":\"2017-05-18T03:49:20+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/medicine.nus.edu.sg\\\/pcm\\\/journal-club-36-holes-in-the-roof-the-protocol-for-reversing-alzheimers-disease\\\/\"},\"wordCount\":223,\"commentCount\":0,\"articleSection\":[\"Events\"],\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"CommentAction\",\"name\":\"Comment\",\"target\":[\"https:\\\/\\\/medicine.nus.edu.sg\\\/pcm\\\/journal-club-36-holes-in-the-roof-the-protocol-for-reversing-alzheimers-disease\\\/#respond\"]}]},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/medicine.nus.edu.sg\\\/pcm\\\/journal-club-36-holes-in-the-roof-the-protocol-for-reversing-alzheimers-disease\\\/\",\"url\":\"https:\\\/\\\/medicine.nus.edu.sg\\\/pcm\\\/journal-club-36-holes-in-the-roof-the-protocol-for-reversing-alzheimers-disease\\\/\",\"name\":\"Journal Club \u2013 36 Holes in the Roof \u2013 The Protocol for Reversing Alzheimer\u2019s Disease - 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