Journal Club – Haemodynamic response during a cognitive task in patients with depressive symptoms: A functional near infrared spectroscopy study

Events   16 November, 2017

Date: 16 November 2017

Time: 8-9AM

Venue: Seminar Room T09-04, Level 9, NUHS Tower Block

Speaker: Ms Syed Fabeha, Postgraduate Student

Chairperson:  A/Prof Roger Ho, Consultant, Dept of Psychological Medicine, NUH

Brief Abstract:

Functional near infrared spectroscopy (fNIRS) is an emerging non-invasive neuroimaging modality that enables direct measurement of oxyhaemoglobin and deoxyhaemoglobin concentrations in the cerebral cortex. Due to tight coupling between neural activity and haemodynamic changes, fNIRS has been used to study the physiological basis of cognitive dysfunction in psychiatric disorders. With growing evidence demonstrating the association between diminished haemodynamic response and depression, we hypothesise that haemoglobin concentration has an inverse relationship with severity of depressive disorders. After discussing fNIRS principles and key findings from published articles, preliminary results from this newly initiated study will be examined.