{"id":6274,"date":"2017-07-14T14:19:57","date_gmt":"2017-07-14T06:19:57","guid":{"rendered":"http:\/\/https:\/\/medicine.nus.edu.sg\/pathweb\/?page_id=6274"},"modified":"2023-04-03T14:38:14","modified_gmt":"2023-04-03T06:38:14","slug":"lymphoid-disorders-clinicopathologic-correlation","status":"publish","type":"page","link":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-clinicopathologic-correlation\/","title":{"rendered":"II. Lymphoid Disorders: Clinicopathologic Correlation"},"content":{"rendered":"\n\n\t<p><strong>How do lymphoid disorders\u00a0manifest clinically?<\/strong><\/p>\n<ol>\n<li>Lymphadenopathy<\/li>\n<li>Inflammatory symptoms \/ signs<\/li>\n<li>Systemic symptoms \/ signs<\/li>\n<\/ol>\n<h3>\n\t\tMINDMAP: Main Clinical manifestations of lymphoid diseases\n\t<\/h3>\n\t<p>If you can&#8217;t play the video, watch it here on YouTube:\u00a0<a href=\"https:\/\/youtu.be\/JnZbtpb7Xgc\" target=\"_blank\" rel=\"noopener\">https:\/\/youtu.be\/JnZbtpb7Xgc<\/a><\/p>\n\t<iframe loading=\"lazy\" src=\"https:\/\/player.vimeo.com\/video\/222623989?title=0&#038;byline=0&#038;portrait=0\" width=\"640\" height=\"360\" frameborder=\"0\" webkitallowfullscreen mozallowfullscreen allowfullscreen><\/iframe><br \/>\n\t<p><strong>CLINICOPATHOLOGIC CORRELATES:<\/strong><\/p>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\">What are some questions to ask in a patient with lymphadenopathy? (Click to expand)<\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<ul>\n<li>\n<ul>\n<li>\n<ul>\n<li>Nature of lymphadenopathy \u00a0&#8211; Localised vs generalised?<\/li>\n<li>Local signs\/symptoms of inflammation &#8211; Pain, tenderness, redness, warmth<\/li>\n<li>Systemic symptoms &#8211; fever, malaise, night sweats (associated with TB and some lymphomas)<\/li>\n<li>Any regional pathology is draining sites &#8211; ulcers, masses, eczem<\/li>\n<li>Past history and Systems review\n<ul>\n<li>Past history &#8211; immunocompromised state (predispose to lymphoma), known malignancy?<\/li>\n<li>Systems review &#8211; history of known malignancy presenting with metastatic nodal disease<\/li>\n<\/ul>\n<\/li>\n<\/ul>\nMore information on a practical approach will be covered in the\u00a0Approach to Lymphadenotpathy Mindmap\u00a0below.<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n\t<p><strong>Let&#8217;s think about the PATIENT:<\/strong><\/p>\n<h3>\n\t\tMINDMAP: Approach to Lymphadenopathy\n\t<\/h3>\n\t<p>If you can&#8217;t play the video, watch it here on YouTube:\u00a0<a href=\"https:\/\/youtu.be\/pitrjBNHNpE\" target=\"_blank\" rel=\"noopener\">https:\/\/youtu.be\/pitrjBNHNpE<\/a><\/p>\n\t<iframe loading=\"lazy\" src=\"https:\/\/player.vimeo.com\/video\/218425747?title=0&#038;byline=0&#038;portrait=0\" width=\"640\" height=\"360\" frameborder=\"0\" webkitallowfullscreen mozallowfullscreen allowfullscreen><\/iframe>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-approach\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tI. Lymphoid Disorders: Approach\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-clinicopathologic-correlation\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tII. Lymphoid Disorders: Clinicopathologic Correlation\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/i-bone-marrow-overview\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tIII. Bone Marrow: Overview\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/ii-haematolymphoid-system-exercises-and-talking-pots\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tIV. Haematolymphoid System: Exercises and Talking Pots\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/haematolymphoid-system-quiz\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tV. Haematolymphoid System: Quiz\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/haematolymphoid-one-page-summary\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tHaematolymphoid One Page Summary\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tHaematolymphoid Chapter Home\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tPathology Demystified\n\t\t\t\t\t<\/a>\n\n","protected":false},"excerpt":{"rendered":"<p>How do lymphoid disorders\u00a0manifest clinically? Lymphadenopathy Inflammatory symptoms \/ signs Systemic symptoms \/ signs MINDMAP: Main Clinical manifestations of lymphoid diseases If you can&#8217;t play the video, watch it here on YouTube:\u00a0https:\/\/youtu.be\/JnZbtpb7Xgc CLINICOPATHOLOGIC CORRELATES: What are some questions to ask in a patient with lymphadenopathy? (Click to expand) Expand Nature of lymphadenopathy \u00a0&#8211; Localised vs [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":6065,"menu_order":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-6274","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NUS Pathweb<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-clinicopathologic-correlation\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:description\" content=\"How do lymphoid disorders\u00a0manifest clinically? Lymphadenopathy Inflammatory symptoms \/ signs Systemic symptoms \/ signs MINDMAP: Main Clinical manifestations of lymphoid diseases If you can&#8217;t play the video, watch it here on YouTube:\u00a0https:\/\/youtu.be\/JnZbtpb7Xgc CLINICOPATHOLOGIC CORRELATES: What are some questions to ask in a patient with lymphadenopathy? (Click to expand) Expand Nature of lymphadenopathy \u00a0&#8211; Localised vs [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-clinicopathologic-correlation\/\" \/>\n<meta property=\"og:site_name\" content=\"NUS Pathweb\" \/>\n<meta property=\"article:modified_time\" content=\"2023-04-03T06:38:14+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-clinicopathologic-correlation\/\",\"url\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-clinicopathologic-correlation\/\",\"name\":\"\",\"isPartOf\":{\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/#website\"},\"datePublished\":\"2017-07-14T06:19:57+00:00\",\"dateModified\":\"2023-04-03T06:38:14+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-clinicopathologic-correlation\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-clinicopathologic-correlation\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-clinicopathologic-correlation\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Pathology Demystified\",\"item\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Haematolymphoid System\",\"item\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"II. Lymphoid Disorders: Clinicopathologic Correlation\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/#website\",\"url\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/\",\"name\":\"NUS Pathweb\",\"description\":\"Pathology made easy\",\"publisher\":{\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/#organization\",\"name\":\"NUS Medicine PathWeb\",\"url\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-content\/uploads\/2020\/08\/NUS-Medicine-Logo.png\",\"contentUrl\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-content\/uploads\/2020\/08\/NUS-Medicine-Logo.png\",\"width\":300,\"height\":61,\"caption\":\"NUS Medicine PathWeb\"},\"image\":{\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.instagram.com\/pathweb\/\",\"https:\/\/www.youtube.com\/channel\/UC3FweZwONWAicB72vF9P5ew\/playlists\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"NUS Pathweb","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-clinicopathologic-correlation\/","og_locale":"en_US","og_type":"article","og_description":"How do lymphoid disorders\u00a0manifest clinically? Lymphadenopathy Inflammatory symptoms \/ signs Systemic symptoms \/ signs MINDMAP: Main Clinical manifestations of lymphoid diseases If you can&#8217;t play the video, watch it here on YouTube:\u00a0https:\/\/youtu.be\/JnZbtpb7Xgc CLINICOPATHOLOGIC CORRELATES: What are some questions to ask in a patient with lymphadenopathy? (Click to expand) Expand Nature of lymphadenopathy \u00a0&#8211; Localised vs [&hellip;]","og_url":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-clinicopathologic-correlation\/","og_site_name":"NUS Pathweb","article_modified_time":"2023-04-03T06:38:14+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-clinicopathologic-correlation\/","url":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-clinicopathologic-correlation\/","name":"","isPartOf":{"@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/#website"},"datePublished":"2017-07-14T06:19:57+00:00","dateModified":"2023-04-03T06:38:14+00:00","breadcrumb":{"@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-clinicopathologic-correlation\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-clinicopathologic-correlation\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/lymphoid-disorders-clinicopathologic-correlation\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/medicine.nus.edu.sg\/pathweb\/"},{"@type":"ListItem","position":2,"name":"Pathology Demystified","item":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/"},{"@type":"ListItem","position":3,"name":"Haematolymphoid System","item":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/haematolymphoid-system-lymph-nodes\/"},{"@type":"ListItem","position":4,"name":"II. Lymphoid Disorders: Clinicopathologic Correlation"}]},{"@type":"WebSite","@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/#website","url":"https:\/\/medicine.nus.edu.sg\/pathweb\/","name":"NUS Pathweb","description":"Pathology made easy","publisher":{"@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/medicine.nus.edu.sg\/pathweb\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/#organization","name":"NUS Medicine PathWeb","url":"https:\/\/medicine.nus.edu.sg\/pathweb\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/#\/schema\/logo\/image\/","url":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-content\/uploads\/2020\/08\/NUS-Medicine-Logo.png","contentUrl":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-content\/uploads\/2020\/08\/NUS-Medicine-Logo.png","width":300,"height":61,"caption":"NUS Medicine PathWeb"},"image":{"@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.instagram.com\/pathweb\/","https:\/\/www.youtube.com\/channel\/UC3FweZwONWAicB72vF9P5ew\/playlists"]}]}},"_links":{"self":[{"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/pages\/6274"}],"collection":[{"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/comments?post=6274"}],"version-history":[{"count":10,"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/pages\/6274\/revisions"}],"predecessor-version":[{"id":36057,"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/pages\/6274\/revisions\/36057"}],"up":[{"embeddable":true,"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/pages\/6065"}],"wp:attachment":[{"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/media?parent=6274"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}