{"id":5893,"date":"2017-06-13T16:04:45","date_gmt":"2017-06-13T08:04:45","guid":{"rendered":"http:\/\/https:\/\/medicine.nus.edu.sg\/pathweb\/?page_id=5893"},"modified":"2023-04-03T15:11:34","modified_gmt":"2023-04-03T07:11:34","slug":"iii-main-diseases-of-bones-and-joints","status":"publish","type":"page","link":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/musculoskeletal-system-demys\/iii-main-diseases-of-bones-and-joints\/","title":{"rendered":"III. Main Diseases of Bones and Joints"},"content":{"rendered":"\n\n\t<p>On this page you will get an overview of the main disease of the JOINTS and BONES.<\/p>\n<p>We will begin by looking at diseases of the<strong> JOINTS.<\/strong><\/p>\n<h3>\n\t\tMindmap: Main Diseases of the Joints\n\t<\/h3>\n\t<p>If you can&#8217;t play the video, watch it here on YouTube: <a href=\"https:\/\/youtu.be\/CKbC_XvXeuo\">https:\/\/youtu.be\/CKbC_XvXeuo<\/a><\/p>\n\t<iframe loading=\"lazy\" src=\"https:\/\/player.vimeo.com\/video\/199765015\" width=\"640\" height=\"481\" frameborder=\"0\" webkitallowfullscreen mozallowfullscreen allowfullscreen><\/iframe>\n\t<p><strong>Case:<\/strong> The patient is a 54 year old man with a very painful swollen left knee. The knee was found to be warm, red and tender, with a large joint effusion. A needle was used to <strong>aspirate<\/strong> the fluid, which was sent to the\u00a0<strong>Pathology\u00a0<\/strong><strong>and\u00a0Microbiology<\/strong>\u00a0<strong>labs.\u00a0<\/strong><\/p>\n<p>Here is what the pathologist will see, on microscopic examination of the fluid, under polarised light microscopy.<\/p>\n<p>What does this picture show?<\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-content\/uploads\/2017\/06\/Gout-joint-fluid-crystals-NUH-case-22gybf1.jpg\" alt=\"OLYMPUS DIGITAL CAMERA\" itemprop=\"image\" height=\"1200\" width=\"1600\" title=\"OLYMPUS DIGITAL CAMERA\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-content\/uploads\/2017\/06\/Gout-birefringence-14v704a.jpg\" alt=\"Gout-birefringence-14v704a\" itemprop=\"image\" height=\"828\" width=\"1100\" title=\"Gout-birefringence-14v704a\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--label-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\">A Painful Swollen Knee <\/a>\n\t\t\t\t\t\t\t\t\t\t\t<a href=\"#\" id=\"fl-accordion--icon-0\" tabindex=\"0\" aria-controls=\"fl-accordion--panel-0\"><i>Expand<\/i><\/a>\n\t\t\t\t\t<p>The picture shows numerous needle shaped crystals that &#8216;glow&#8217; under polarised light microscopy. This morphologic picture is compatible with uric acide crystals.<\/p>\n<p>If a colour filter were used, the presence of negative birefringence will be noted (2nd picture) &#8211; i.e. crystals pointing in a certain direction will appear yellow, while those at right angles to that appear blue.<\/p>\n\t<p>We will now move on toe disease of the <strong>BONES.<\/strong><\/p>\n<h3>\n\t\tMindmap: Main Diseases of the Bones (Part 1)\n\t<\/h3>\n\t<p>If you can&#8217;t play the video, watch it here on YouTube: <a href=\"https:\/\/youtu.be\/JYP11ibOus4\" target=\"_blank\" rel=\"noopener\">https:\/\/youtu.be\/JYP11ibOus4<\/a><\/p>\n\t<iframe loading=\"lazy\" src=\"https:\/\/player.vimeo.com\/video\/199783138\" width=\"640\" height=\"478\" frameborder=\"0\" webkitallowfullscreen mozallowfullscreen allowfullscreen><\/iframe>\n<h3>\n\t\tMindmap: Bone Neoplasms &#8211; Main Diseases of the Bones (Part 2)\n\t<\/h3>\n\t<p>If you can&#8217;t play the video, watch it here on YouTube: <a href=\"https:\/\/youtu.be\/nJ676resEdQ\" target=\"_blank\" rel=\"noopener\">https:\/\/youtu.be\/nJ676resEdQ<\/a><\/p>\n\t<iframe loading=\"lazy\" src=\"https:\/\/player.vimeo.com\/video\/199765004\" width=\"640\" height=\"481\" frameborder=\"0\" webkitallowfullscreen mozallowfullscreen allowfullscreen><\/iframe>\n\t<p>This diagram illustrates the localisation of benign and malignant tumours within long bones:<\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-content\/uploads\/2017\/06\/Bone-tuours-with-ref-xusk0r.jpg\" alt=\"Bone-tuours-with-ref-xusk0r\" itemprop=\"image\" height=\"975\" width=\"1082\" title=\"Bone-tuours-with-ref-xusk0r\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/musculoskeletal-system-demys\/i-bone-and-joint-diseases-clinical-principles\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tI. Bone and Joint Diseases: Clinical Principles\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/musculoskeletal-system-demys\/ii-bone-and-joint-diseases-overview\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tII. Bone and Joint Diseases: Overview\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/musculoskeletal-system-demys\/iii-main-diseases-of-bones-and-joints\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tIII.Main Diseases of Bones and Joints\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/musculoskeletal-system-demys\/talking-pots-clinicopathologic-correlation\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tIV.  Musculoskeletal System: Talking Pots \n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/musculoskeletal-system-demys\/a-real-life-case-and-quiz\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tV. A Real Life Case and Quiz\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/musculoskeletal-system-demys\/a-real-life-case-part-2\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tVI. A Real Life Case Demo\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/musculoskeletal-system-demys\/one-page-summary-study-notes\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tMusculoskeletal System: Study Notes and One Page Summary\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/musculoskeletal-system-demys\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tMusculoskeletal System Chapter Home\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tPathology Demystified\n\t\t\t\t\t<\/a>\n\n","protected":false},"excerpt":{"rendered":"<p>On this page you will get an overview of the main disease of the JOINTS and BONES. We will begin by looking at diseases of the JOINTS. Mindmap: Main Diseases of the Joints If you can&#8217;t play the video, watch it here on YouTube: https:\/\/youtu.be\/CKbC_XvXeuo Case: The patient is a 54 year old man with [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":5876,"menu_order":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-5893","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NUS Pathweb<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/musculoskeletal-system-demys\/iii-main-diseases-of-bones-and-joints\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:description\" content=\"On this page you will get an overview of the main disease of the JOINTS and BONES. 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