{"id":5753,"date":"2017-06-05T01:38:49","date_gmt":"2017-06-04T17:38:49","guid":{"rendered":"http:\/\/https:\/\/medicine.nus.edu.sg\/pathweb\/?page_id=5753"},"modified":"2023-04-03T13:28:43","modified_gmt":"2023-04-03T05:28:43","slug":"iii-main-diseases-approach","status":"publish","type":"page","link":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iii-main-diseases-approach\/","title":{"rendered":"III. Main Diseases &#8211; Approach"},"content":{"rendered":"\n\n\t<p>When looking at liver diseases, keep in mind:<\/p>\n<ul> \t\n<li><strong>Aetiologic <\/strong>category &#8211; Helps you to remember cause and pathogenesis (eg. Vascular; Infectious, Neoplastic etc)<\/li>\n\n<li><strong>Cellular\/subcellular <\/strong>and hence <strong>functional <\/strong>components affected (eg. hepatocytes; bile canaliculi; bile duct epithelium; central veins\/sinusoids)\n<ul> \t\n<li>Helps to work out morphology (gross and micro)<\/li>\n\n<li>Helps you work out clinical manifestations<\/li>\n\n<li>eg. Alcoholic liver disease -&gt; \u00a0abnormal lipid metabolism, free radicals, cytokines -&gt; \u00a0 steatosis, steatohepatitis -&gt; \u00a0necrosis of hepatocytes \u00a0(Alcoholic Hepatitis) -&gt; \u00a0nodular regeneration of hepatocytes with fibrosis (Cirrhosis) -&gt; \u00a0portal hypertension, eventual Liver failure<\/li>\n<\/ul>\n<\/li>\n<\/ul>\n<p><strong>Here is a video mindmap of some liver diseases according to aetiologic\u00a0categories.<\/strong><\/p>\n<h3>\n\t\tMINDMAP: Liver diseases \n\t<\/h3>\n\t<p>If you can&#8217;t play the video, watch it here on YouTube: <a href=\"https:\/\/youtu.be\/PGoocCEyNSY\" target=\"_blank\" rel=\"noopener\">https:\/\/youtu.be\/PGoocCEyNSY<\/a><\/p>\n\t<iframe loading=\"lazy\" src=\"https:\/\/player.vimeo.com\/video\/192088953\" width=\"640\" height=\"481\" frameborder=\"0\" webkitallowfullscreen mozallowfullscreen allowfullscreen><\/iframe>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/i-overview-what-is-normal\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tI. Overview: What&#8217;s Normal\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/hepato-ii-clinicopathologic-correlates\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tII. Clinicopathologic Correlates\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iii-main-diseases-approach\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tIII. Main Diseases: Approach\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iv-liver-pots-approach\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tIV. Liver Pots: Approach\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/hepatobiliary-system-quiz\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tV. Hepatobiliary System: Quiz\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/hepatobiliary-system-one-page-summary-study-notes\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tHepatobiliary System: Study Notes and One Page Summary\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tHepatobiliary System Chapter Home\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tPathology Demystified\n\t\t\t\t\t<\/a>\n\n","protected":false},"excerpt":{"rendered":"<p>When looking at liver diseases, keep in mind: Aetiologic category &#8211; Helps you to remember cause and pathogenesis (eg. Vascular; Infectious, Neoplastic etc) Cellular\/subcellular and hence functional components affected (eg. hepatocytes; bile canaliculi; bile duct epithelium; central veins\/sinusoids) Helps to work out morphology (gross and micro) Helps you work out clinical manifestations eg. Alcoholic liver [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":5737,"menu_order":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-5753","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NUS Pathweb<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iii-main-diseases-approach\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:description\" content=\"When looking at liver diseases, keep in mind: Aetiologic category &#8211; Helps you to remember cause and pathogenesis (eg. Vascular; Infectious, Neoplastic etc) Cellular\/subcellular and hence functional components affected (eg. hepatocytes; bile canaliculi; bile duct epithelium; central veins\/sinusoids) Helps to work out morphology (gross and micro) Helps you work out clinical manifestations eg. Alcoholic liver [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iii-main-diseases-approach\/\" \/>\n<meta property=\"og:site_name\" content=\"NUS Pathweb\" \/>\n<meta property=\"article:modified_time\" content=\"2023-04-03T05:28:43+00:00\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data1\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iii-main-diseases-approach\/\",\"url\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iii-main-diseases-approach\/\",\"name\":\"\",\"isPartOf\":{\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/#website\"},\"datePublished\":\"2017-06-04T17:38:49+00:00\",\"dateModified\":\"2023-04-03T05:28:43+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iii-main-diseases-approach\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iii-main-diseases-approach\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iii-main-diseases-approach\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Pathology Demystified\",\"item\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/\"},{\"@type\":\"ListItem\",\"position\":3,\"name\":\"Hepatobiliary System\",\"item\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/\"},{\"@type\":\"ListItem\",\"position\":4,\"name\":\"III. Main Diseases &#8211; Approach\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/#website\",\"url\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/\",\"name\":\"NUS Pathweb\",\"description\":\"Pathology made easy\",\"publisher\":{\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/#organization\",\"name\":\"NUS Medicine PathWeb\",\"url\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-content\/uploads\/2020\/08\/NUS-Medicine-Logo.png\",\"contentUrl\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-content\/uploads\/2020\/08\/NUS-Medicine-Logo.png\",\"width\":300,\"height\":61,\"caption\":\"NUS Medicine PathWeb\"},\"image\":{\"@id\":\"https:\/\/medicine.nus.edu.sg\/pathweb\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.instagram.com\/pathweb\/\",\"https:\/\/www.youtube.com\/channel\/UC3FweZwONWAicB72vF9P5ew\/playlists\"]}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"NUS Pathweb","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iii-main-diseases-approach\/","og_locale":"en_US","og_type":"article","og_description":"When looking at liver diseases, keep in mind: Aetiologic category &#8211; Helps you to remember cause and pathogenesis (eg. Vascular; Infectious, Neoplastic etc) Cellular\/subcellular and hence functional components affected (eg. hepatocytes; bile canaliculi; bile duct epithelium; central veins\/sinusoids) Helps to work out morphology (gross and micro) Helps you work out clinical manifestations eg. Alcoholic liver [&hellip;]","og_url":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iii-main-diseases-approach\/","og_site_name":"NUS Pathweb","article_modified_time":"2023-04-03T05:28:43+00:00","twitter_card":"summary_large_image","twitter_misc":{"Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iii-main-diseases-approach\/","url":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iii-main-diseases-approach\/","name":"","isPartOf":{"@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/#website"},"datePublished":"2017-06-04T17:38:49+00:00","dateModified":"2023-04-03T05:28:43+00:00","breadcrumb":{"@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iii-main-diseases-approach\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iii-main-diseases-approach\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/iii-main-diseases-approach\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/medicine.nus.edu.sg\/pathweb\/"},{"@type":"ListItem","position":2,"name":"Pathology Demystified","item":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/"},{"@type":"ListItem","position":3,"name":"Hepatobiliary System","item":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/hepatobiliary-system\/"},{"@type":"ListItem","position":4,"name":"III. Main Diseases &#8211; Approach"}]},{"@type":"WebSite","@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/#website","url":"https:\/\/medicine.nus.edu.sg\/pathweb\/","name":"NUS Pathweb","description":"Pathology made easy","publisher":{"@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/medicine.nus.edu.sg\/pathweb\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/#organization","name":"NUS Medicine PathWeb","url":"https:\/\/medicine.nus.edu.sg\/pathweb\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/#\/schema\/logo\/image\/","url":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-content\/uploads\/2020\/08\/NUS-Medicine-Logo.png","contentUrl":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-content\/uploads\/2020\/08\/NUS-Medicine-Logo.png","width":300,"height":61,"caption":"NUS Medicine PathWeb"},"image":{"@id":"https:\/\/medicine.nus.edu.sg\/pathweb\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.instagram.com\/pathweb\/","https:\/\/www.youtube.com\/channel\/UC3FweZwONWAicB72vF9P5ew\/playlists"]}]}},"_links":{"self":[{"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/pages\/5753"}],"collection":[{"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/comments?post=5753"}],"version-history":[{"count":7,"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/pages\/5753\/revisions"}],"predecessor-version":[{"id":36015,"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/pages\/5753\/revisions\/36015"}],"up":[{"embeddable":true,"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/pages\/5737"}],"wp:attachment":[{"href":"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-json\/wp\/v2\/media?parent=5753"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}