{"id":5377,"date":"2017-05-05T13:05:39","date_gmt":"2017-05-05T05:05:39","guid":{"rendered":"http:\/\/https:\/\/medicine.nus.edu.sg\/pathweb\/?page_id=5377"},"modified":"2023-04-03T14:09:58","modified_gmt":"2023-04-03T06:09:58","slug":"breast-iii-clinicopathologic-correlation","status":"publish","type":"page","link":"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/breast-pathology\/breast-iii-clinicopathologic-correlation\/","title":{"rendered":"III. Clinicopathologic Correlation"},"content":{"rendered":"\n\n\t<p>An understanding of the main clinical manifestations of breast disease coupled with knowledge of the main diseases enables you to correlate clinical features with pathology (clinicopathologic correlation). The next step is to work out specific clinical manifestations based on your knowledge of disease behaviour and morphology.<\/p>\n<p>This table below highlights <strong>some <\/strong>examples of conditions and their clinical features. Fill up more conditions are you go along.<\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-content\/uploads\/2017\/05\/Table-Clinicopath.jpg\" alt=\"Table-Clinicopath\" itemprop=\"image\" height=\"1133\" width=\"1827\" title=\"Table-Clinicopath\" onerror=\"this.style.display='none'\"  \/>\n\t<p>Another very important clinical presentation is the <strong>asymptomatic patient with imaging abnormalities from breast screening.<\/strong><\/p>\n<ul>\n<li>Why screen? &#8211; Detect smaller (earlier) lesions &#8211; threshold size for detection is around 1cm (compared to palpation which is around 2cm)<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>2 main parameters evaluated<\/p>\n<ul>\n<li>Densities<\/li>\n<li>Calcifications (worrying: small, irregular, numerous, clustered; linear branching (DCIS))<\/li>\n<\/ul>\n<p>&nbsp;<\/p>\n<p>Don&#8217;t forget <strong>Systemic symptoms <\/strong>too, which can occur in advanced disseminated malignancy; or infections, as well as hormonal or developmental conditions.<\/p>\n<h3>\n\t\tMINDMAP: Main Clinical Presentations of Breast Diseases\n\t<\/h3>\n\t<p>If you can&#8217;t play the video, watch it here on YouTube:<a href=\"https:\/\/youtu.be\/r-C6TLJYQEc\" target=\"_blank\" rel=\"noopener\">\u00a0https:\/\/youtu.be\/r-C6TLJYQEc<\/a><\/p>\n\t<iframe loading=\"lazy\" src=\"https:\/\/player.vimeo.com\/video\/200775137\" width=\"640\" height=\"481\" frameborder=\"0\" webkitallowfullscreen mozallowfullscreen allowfullscreen><\/iframe>\n\t<p><strong>KNOW YOUR LEMONS<\/strong>: Look at this picture from a campaign on Breast Cancer Awareness. Can you figure out the underlying pathology for each lemon?<\/p>\n<p><strong><a href=\"https:\/\/www.worldwidebreastcancer.org\/\">https:\/\/www.worldwidebreastcancer.org<\/a><\/strong><\/p>\n\t\t\t\t<img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/medicine.nus.edu.sg\/pathweb\/wp-content\/uploads\/2017\/05\/knowyourlemonsdotcom-12signs-29d918y.png\" alt=\"knowyourlemonsdotcom-12signs-29d918y\" itemprop=\"image\" height=\"1060\" width=\"1500\" title=\"knowyourlemonsdotcom-12signs-29d918y\" onerror=\"this.style.display='none'\"  \/>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/breast-pathology\/i-overview-and-approach\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tI. Overview and Approach\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/breast-pathology\/ii-main-diseases-of-the-breast\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tII. Main Diseases of the Breast\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/breast-pathology\/breast-iii-clinicopathologic-correlation\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tIII. Clinicopathologic Correlation\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/breast-pathology\/breast-talking-pots-and-slides\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tIV. Breast Pathology: Talking Pots and Slides\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/breast-pathology\/breast-quiz\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tV. Breast: Quizzes\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/breast-pathology\/breast-pathology-one-page-summary-study-notes\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tBreast Pathology: Study Notes and One Page Summary\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/breast-pathology\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tBreast Pathology Chapter Home\n\t\t\t\t\t<\/a>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/\" target=\"_self\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tPathology Demystified\n\t\t\t\t\t<\/a>\n\t<p>See how, in <strong>real life,<\/strong> the Pathologist would handle a breast case, from the patient to the final pathology report.<\/p>\n<p>&nbsp;<\/p>\n\t\t\t<a href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/pathology-in-action-real-life-cases\/pathology-in-action-a-breast-lump\/\" target=\"_blank\" role=\"button\" rel=\"noopener\">\n\t\t\t\t\t\t\tA Real Life Case: Breast\n\t\t\t\t\t<\/a>\n\n","protected":false},"excerpt":{"rendered":"<p>An understanding of the main clinical manifestations of breast disease coupled with knowledge of the main diseases enables you to correlate clinical features with pathology (clinicopathologic correlation). The next step is to work out specific clinical manifestations based on your knowledge of disease behaviour and morphology. This table below highlights some examples of conditions and [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":5358,"menu_order":0,"comment_status":"open","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-5377","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>NUS Pathweb<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medicine.nus.edu.sg\/pathweb\/pathology-demystified\/breast-pathology\/breast-iii-clinicopathologic-correlation\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:description\" content=\"An understanding of the main clinical manifestations of breast disease coupled with knowledge of the main diseases enables you to correlate clinical features with pathology (clinicopathologic correlation). 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