Research Groups

Identification of novel natural product compounds that can suppress NF-kB activation to treat cancer.
Developing new therapies for breast and endometrial carcinoma targeting hormones and secreted proteins.
Characterization of DEAD-box RNA Helicases regulating cell proliferation, migration & drug resistance in breast cancer.
Identification of deubiquitinating enzymes overexpressed in cancers that act as potent TGF-β pathway activators.
Developing carbon-based nanoparticle drug-delivery platforms for enhanced diagnosis and treatment of cancer
Understanding the roles of nuclear receptors and epigenetics in regulating gene expression in breast cancer.

Publication Impact Factor Award (Adjunct Publishing), Curtin University, Australia, 2014 (Alan Prem Kumar)

Advances in the diagnosis, epidemiology, neuroimaging and prevention strategies for vascular cognitive impairment.
Role of H2S in ischaemic injuries and the therapeutic potential of inhibiting production of H2S.
Neuroprotective effects of H2S in Parkinson’s disease and other neurodegenerative diseases.
Postmortem human brain studies of neurochemical markers and mechanisms of dementia.
Stapled peptide ligands for the Relaxin-3/RXFP3 system as a novel target for neuropsychiatric disorders.
Novel, non-amyloidogenic functions of the amyloid precursor protein.
Chemical biology and drug design for glutamate receptor and phospholipase A2 targets in pain.
Epigenetic regulation of visual and somatosensory cortical neuroplasticity.
The study of the use of ginseng and ginseng products in Singapore

GlaxoSmithKline Academic Centre of Excellence Research Awards, 2010 (Chris Chen and Gavin Dawe)

Validation and characterization of bioactive molecules: andrographilide, artusenate and vitamin E isoform.
Drug discovery and development for the treatment of respiratory diseases including asthma and OCPD.
Analysis of fundamental lipid-signaling systems that regulate cellular processes.
Validation of novel drugs for the treatment of pain and hearing
Role of H2S in inflammatory responses.
Mechanisms of neuroinflammation in mild cognitive impairment and their contribution to development of dementia.
Evaluation of natural products for their effects on blood pressure, blood sugar, and lipids in experimental animals.
Effect of disease conditions on drug metabolism, transport, disposition, efficacy, or toxicity.
Reproductive endocrinology

Department of Pharmacology