The Heat Resilience & Performance Centre (HRPC) at the Yong Loo Lin School of Medicine, National University of Singapore (NUS Medicine) has been officially designated as the Global Heat Health Information Network (GHHIN) Southeast Asia Hub, a recognition that underscores its leading role in advancing heat resilience. This designation highlights the Centre’s expertise in addressing the growing challenges of heat-related health risks in the region. With this appointment, the Centre is poised to play a pivotal role in working with the region to shape strategies, research, and policies aimed at mitigating the impact of extreme heat on public health, demonstrating its commitment to building resilience in the face of climate change.