A/Prof Kenneth Ban Hon Kim - Department of Biomedical Informatics

BAN HON KIM, Kenneth

Associate Professor

Curriculum Vitae

Brief Introduction Journals & Publications

Brief Introduction

Kenneth obtained his BSc (Hons) and MBBS degrees from NUS and a PhD in Cancer Biology from Stanford University, He completed his postdoctoral training in mouse cancer genetics at the Institute of Molecular and Cell Biology (IMCB) Singapore prior to joining the Department of Biochemistry at NUS.

He has been a medical educator since joining NUS and serves as the Phase I Director at the Yong Loo Lin School of Medicine, helping to develop and support initiatives to build students’ understanding of how basic science concepts can linked to clinical applications through interactive teaching methodologies and technology-enhanced learning platforms. He currently also leads the development of a longitudinal Health Informatics track that aims to build foundational competencies in data science for our medical students, empowering them to be innovators who are able to use data-driven approaches to derive new insights for improving healthcare outcomes.

Research Interest

Prostate and Breast Cancer Genetics
Mouse Models of Cancer
Transposon Mutagenesis for Cancer Gene Discovery and Validation
Cell Cycle Regulation, Cellular Senescence, Cell Fate Determination

Journals & Publications

Selected Publications

Wong ES*, Ban KH*, Mutalif R, Jenkins NA, Copeland NG, Stewart CL. A simple procedure for the efficient derivation of mouse ES cells. Methods Enzymol. 2010;476:265-83 *Equal contribution.
Torres JZ, Ban KH, Jackson PK. A specific form of phospho protein phosphatase 2 regulates anaphase-promoting complex/cyclosome association with spindle poles. Mol Biol Cell. 2010 Mar 15;21(6):897-904.
Verschuren EW, Ban KH, Masek MA, Lehman NL, Jackson PK. Loss of Emi1-dependent anaphase-promoting complex/cyclosome inhibition deregulates E2F target expression and elicits DNA damage-induced senescence. Mol Cell Biol. 2007 Nov;27(22):7955-65.
Ban KH, Torres JZ, Miller JJ, Mikhailov A, Nachury MV, Tung JJ, Rieder CL, Jackson PK. The END network couples spindle pole assembly to inhibition of the anaphase-promoting complex/cyclosome in early mitosis. Dev Cell. 2007 Jul;13(1):29-42.
Lee AT, Ren J, Wong ET, Ban KH, Lee LA, Lee CG. The hepatitis B virus X protein sensitizes HepG2 cells to UV light-induced DNA damage. J Biol Chem. 2005 Sep 30;280(39):33525-35.
Tung JJ, Hansen DV, Ban KH, Loktev AV, Summers MK, Adler JR 3rd, Jackson PK. A role for the anaphase-promoting complex inhibitor Emi2/XErp1, a homolog of early mitotic inhibitor 1, in cytostatic factor arrest of Xenopus eggs. Proc Natl Acad Sci U S A. 2005 Mar 22;102(12):4318-23.
Hansen DV, Loktev AV, Ban KH, Jackson PK. Plk1 regulates activation of the anaphase promoting complex by phosphorylating and triggering SCFbetaTrCP-dependent destruction of the APC Inhibitor Emi1. Mol Biol Cell. 2004 Dec;15(12):5623-34.
Lee CG, Ren J, Cheong IS, Ban KH, Ooi LL, Yong Tan S, Kan A, Nuchprayoon I, Jin R, Lee KH, Choti M, Lee LA. Expression of the FAT10 gene is highly upregulated in hepatocellular carcinoma and other gastrointestinal and gynecological cancers. Oncogene. 2003 May 1;22(17):2592-603.

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Curriculum Vitae

Research Interest