{"id":869,"date":"2020-02-18T16:41:44","date_gmt":"2020-02-18T16:41:44","guid":{"rendered":"https:\/\/medicine.nus.edu.sg\/bch\/?page_id=869"},"modified":"2020-02-26T06:40:13","modified_gmt":"2020-02-26T06:40:13","slug":"grants","status":"publish","type":"page","link":"https:\/\/medicine.nus.edu.sg\/bch\/lim-yoon-pins-lab\/research\/grants\/","title":{"rendered":"Grants"},"content":{"rendered":"<h2 style=\"text-align: left;\">Research Grants Awarded<\/h2>\n<h3 style=\"text-align: left;\">I) AS PRINCIPAL INVESTIGATOR<\/h3>\n<ol class=\"ol-listing\" style=\"text-align: left;\">\n<li style=\"list-style-type: none;\">\n<ol class=\"ol-listing\">\n<li>National Medical Research Council (NMRC) \u2013 Open Fund Individual Research Grant OF-IRG16nov012 &#8211; Two is better than one \u2013 Her2 in combination with WBP2 improves anti-Her2 precision medicine in breast cancer. $ 879, 900.00 for 2017 to 2020<\/li>\n<p><\/p>\n<li>Ministry of Education Tier 2 Grant &#8211; MOE2016-T2-2-007 &#8211; Reversible Control of WBP2 Oncogene by Tumor Suppressors in breast cancer. $560,426 for 2017 to 2020<\/li>\n<p><\/p>\n<li>National Medical Research Council (NMRC) \u2013 Cooperative Basic Research Grant (CBRG) NMRC\/CBRG\/0033\/2013 \u2013 TRPV4 Calcium Permeable Channel, A Novel Breast Cancer Metastasis Effecter. $906,400 for 2014 to 2017<\/li>\n<p><\/p>\n<li>National Medical Research Council (NMRC) \u2013 Cooperative Basic Research Grant \u2013 Novel Drug Targets for Gastric Cancer Therapy. $1,167,750 for 2012 to 2015.<\/li>\n<p><\/p>\n<li>A*STAR Biomedical Research Council (BMRC) 10\/1\/21\/19\/657. WBP2, a novel breast cancer oncogene &amp; candidate for targeted therapeutics? $750,000 for 2011 to 2014.<\/li>\n<p><\/p>\n<li>A*STAR Exploit Technologies F09\/X\/037_c. DNA Aptamer Diagnostics for Cancer and Disease. $933,000 for 2010 to 2013.<\/li>\n<p><\/p>\n<li>A*STAR Biomedical Research Council (BMRC) 07\/1\/21\/19\/526. Novel Tyrosine Kinase Substrates of Oncogenic EGFR Signaling. S$600, 000 for 2008 to 2010.<\/li>\n<p><\/p>\n<li>A*STAR Biomedical Research Council (BMRC) 06\/1\/21\/19\/468. Molecular Changes During Breast Cancer Progression. S$666, 000 for 2007 to 2010.<\/li>\n<p><\/p>\n<li>A*STAR Singapore Cancer Syndicate (SCS) BU0043. Multi-center PEPTidomics IniTiativE (PEPTITE) and biomarkers for predicting response in target-directed cancer therapeutics. S$1,900,000 for 2006 &#8211; 2010.<\/li>\n<p><\/p>\n<li>A*STAR Biomedical Research Council (BMRC) 04\/1\/21\/19\/368. Phosphoproteomic fingerprinting and identification of activated tyrosine kinases and substrates in laser-captured microdissection-purified human breast cancer epithelial cells as potential molecular markers. S$816,500 for 2005 to 2008.<\/li>\n<p>\n\t\t<\/ol>\n<\/li>\n<\/ol>\n<hr \/>\n<h3 style=\"text-align: left;\">II) AS CO-INVESTIGATOR<\/h3>\n<ol class=\"ol-listing\" style=\"text-align: left;\">\n<li style=\"list-style-type: none;\">\n<ol class=\"ol-listing\">\n<li>National University Health System Summit Research Program (SRP). Co-I with Tai E-Shyong &#8211; Metabolic Disease. $1, 897, 000 for 2016 to 2018.<\/li>\n<p><\/p>\n<li>National Medical Research Council (NMRC), Clinician Scientist Individual Research Grant (CS-IRF). Co-I with Peter Lobie &#8211; Generation of inhibitors to trefoil factor-3 for preclinical development in oncology. $952, 149 for 2016 \u2013 2019.<\/li>\n<p><\/p>\n<li>National Medical Research Council (NMRC), Clinical Scientist Award &#8211; MH 95:03\/1-7. Co-I with Tai E-Shyong \u2013 Understanding ethnic differences in insulin resistance and obesity dependent\/independent pathways leading to insulin resistance by studying substrates involved in insulin signaling in human myoblasts. $1,749,224.21 for 2015 \u2013 2020.<\/li>\n<p><\/p>\n<li>MOE Tier 1. Co-I with Chua Kim Lee &#8211; The role of DNA damage in the rapid development of multidrug-resistant Acinetobacter baumannii. $150,000 for 2014 to 2016<\/li>\n<p><\/p>\n<li>National Medical Research Council (NMRC), New Investigator Grant (NIG). Co-Investigator with Ng Chin Hin &#8211; To identify biomarker in the plasma of a newly diagnosed Acute Myeloid Leukemia that correlates with leukemic stem cell load in the marrow at diagnosis. $181,000 for 2012 to 2015.<\/li>\n<p><\/p>\n<li>National Medical Research Council (NMRC), New Investigator Grant (NIG). Co-Investigator with Dr Anand Jeyasekharan &#8211; Development of Biomarkers for Contrast Enhanced Endoscopy in Gastric Cancer. $200,000 for 2012 to 2015.<\/li>\n<p><\/p>\n<li>National Medical Research Council (NMRC), Cooperative Basic Research Grant (CBRG)\/New Investigator Grant (NIG). Co-Investigator with A\/Ps Louis Tong and Vinay Tergaonkar &#8211; A human ocular surface disease constituted in mouse, from molecular targets to priming of human pterygium derived cells. $196,457 for 2012 to 2015.<\/li>\n<p><\/p>\n<li>National Medical Research Council (NMRC) -Translational and Clinical Program (TCR) \u2013 NMRC\/TCR\/001\/2007. Co-investigator with Professor Yeoh Khay Guan along with 18 other co-investigators. &#8211; Singapore Gastric Cancer Consortium &#8211; Improving Outcomes for Our Patients. $25 million for 2007 to 2012. ($1.68 million is managed directly by Lim Yoon Pin).<\/li>\n<p><\/p>\n<li>Academic Research Fund (NUS). Co-PI with Dr Chong Poh Kuan. Mouse Model for Biomarker Discovery in Gastric Cancer for Early Detection. $173,000 for 2008-2010.<\/li>\n<p><\/p>\n<li>A*STAR Singapore Cancer Syndicate (SCS) BU0063. Co-PI with Professor Hew Choy Leong. Oncoproteomics in gastric cancer biomarker discovery. S$571,667 for 2005-2008. (Sum indicated is managed independently by Lim Yoon Pin).<\/li>\n<p><\/p>\n<li>A*STAR Singapore Cancer Syndicate (SCS). Co-Investigator with Professors Patrick Tan and Malcolm Paterson. Fine scale mapping of cancer markers using comparative genome hybridization (CGH). S$320,000 for 2004.<\/li>\n<p>\n\t\t<\/ol>\n<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>Research Grants Awarded I) AS PRINCIPAL INVESTIGATOR National Medical Research Council (NMRC) \u2013 Open Fund Individual Research Grant OF-IRG16nov012 &#8211;&#8230;<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":837,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":""},"class_list":["post-869","page","type-page","status-publish","hentry"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v26.4 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>Grants - Department of Biochemistry \u2013 School of Medicine, National University of Singapore<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medicine.nus.edu.sg\/bch\/lim-yoon-pins-lab\/research\/grants\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Grants - 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