{"id":544,"date":"2020-01-23T03:09:23","date_gmt":"2020-01-23T03:09:23","guid":{"rendered":"https:\/\/medicine.nus.edu.sg\/bch\/?post_type=faculty&p=544"},"modified":"2024-09-30T20:43:55","modified_gmt":"2024-09-30T12:43:55","slug":"tan-theresa-may-chin","status":"publish","type":"faculty","link":"https:\/\/medicine.nus.edu.sg\/bch\/faculty\/tan-theresa-may-chin\/","title":{"rendered":"Tan May Chin, Theresa"},"content":{"rendered":"

27Affiliations<\/h3>\n

Associate Professor, Department of Biochemistry, Yong Loo Lin School of Medicine, NUS.
\nAssistant Dean (Academic Affairs), Yong Loo Lin School of Medicine, NUS.<\/p>\n

Research Interest<\/h3>\n

* Sequence-specific strategies for inhibition of Hepatitis B viral gene expression.
\n* Role of microRNAs in liver diseases.
\n* Regulation of expression of sulfotransferases (SULTs).
\n* Regulation of expression of the multidrug resistance protein (MRP\/ABCC) subfamily of transporters.<\/p>\n

Selected Publications<\/h3>\n
    \n
  1. Li Y, Tan W, Neo TW, Aung MO, Wasser S, Lim SG,\u00a0<\/span>Tan TM<\/b>. Role of the miR-106b-25 microRNA cluster in hepatocellular carcinoma.\u00a0<\/span>Cancer Sci<\/i>. 2009 Jul;100(7):1234-42.<\/li>\n
  2. Tan EL,\u00a0<\/span>Tan TM<\/b>, Chow V, Poh CL. Inhibition of enterovirus 71 in virus-infected mice by RNA interference.\u00a0<\/span>Mol Ther<\/i>. 2007 Nov;15(11):1931-8.<\/li>\n
  3. TMC Tan<\/b>, Yang F, Fu H, Raghavendra MS and Lam Y. (2007) Traceless Solid-Phase Synthesis and Biological Evaluation of Purine Analogs as Inhibitors of Multidrug Resistance Protein 4. Journal of\u00a0<\/span>Combinatorial Chemistry<\/i>, 9: 210-218.<\/li>\n
  4. TMC Tan<\/b>, Chen Y, Kong KH, Bai J, Li Y, Lim SG, Ang TH and Lam Y. (2006) Synthesis and the biological evaluation of 2-benzenesulfonylalkyl-5-substituted-sulfanyl-[1,3,4]-oxadiazoles as potential anti-hepatitis B virus agents.\u00a0<\/span>Antiviral Res<\/i>. 71(1):7-14.<\/li>\n
  5. Bai J, Lai L, Yeo H, Goh B and\u00a0<\/span>Tan TMC<\/b>. (2004) Multidrug resistance protein 4 (MRP4\/ABCC4) mediates efflux of bimane-glutathione. Int. J. Biochem.\u00a0<\/span>Cell Biol<\/i>. 36(2): 247-257.<\/li>\n
  6. Yang S,\u00a0<\/span>Tan TMC<\/b>, Wee A and Leow CK. (2004) Mitochondrial respiratory function and antioxidant capacity in normal and cirrhotic livers following partial hepatectomy.\u00a0<\/span>Cell Mol. Life Sci<\/i>. 61(2): 220-229.<\/li>\n
  7. Li Y, Wasser S, Lim SG and\u00a0<\/span>TMC Tan<\/b>. (2004) Genome-wide expression profiling of RNA interference of hepatitis B virus replication.\u00a0<\/span>Cell Mol. Life Sci<\/i>. 61(16): 2113-2124.<\/li>\n
  8. Lai L and\u00a0<\/span>Tan TMC<\/b>. (2002) Role of glutathione in the multidrug resistance protein 4 (MRP4\/ABCC4) mediated efflux of cAMP and resistance to purine analogs.\u00a0<\/span>Biochem. J<\/i>. 361: 497-503.<\/li>\n<\/ol>\n","protected":false},"featured_media":432,"parent":0,"menu_order":27,"template":"","faculty_category":[12,58],"class_list":["post-544","faculty","type-faculty","status-publish","has-post-thumbnail","hentry","faculty_category-academic-faculty","faculty_category-academic-faculty-academic-faculty"],"acf":[],"yoast_head":"\nTan May Chin, Theresa - Department of Biochemistry \u2013 School of Medicine, National University of Singapore<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/medicine.nus.edu.sg\/bch\/faculty\/tan-theresa-may-chin\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Tan May Chin, Theresa - Department of Biochemistry \u2013 School of Medicine, National University of Singapore\" \/>\n<meta property=\"og:description\" content=\"27Affiliations Associate Professor, Department of Biochemistry, Yong Loo Lin School of Medicine, NUS. 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