Our mission: To provide researchers at NUH and NUS with high quality samples and associated clinical information in a manner that is safe, efficient and ethical.
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Tissue Banking in Singapore -
An Evolving Enterprise
18 March 2016
Tissue Banking In Singapore - An
Evolving Enterprise, by Dr. Chan Tuck Wai.
(Original article posted in "Vol 20, No 02, Febuary 2016 - Biomedical Research Governance")
TR Cancer Tissues
27 March 2017
updated on a quarterly basis.
Central Nervous System
Lip, Oral Cavity and Pharynx
Mesothelial and Soft Tissue
Male Genital Organs
Others and Unspecified
Ill Defined Sites
*Include matched and unmatched specimens
Biobanking budget in grant proposal
01 April 2017
The national grant funding body, eg, NMRC, had specified that the cost of acquiring bio-specimen materials should be factored in the grant application.
Cost recovery for material obtained or services provided by TR is essential to maintain the operational feasibility and sustainability of the facility. TR is a not-for-profit, BRC (Biological Resource Centre) facility. The bio-banking pricing information reflects costs associated with consumables and costs related to sample collection, processing, storage and distribution charges. TR will be able to assist in the budgeting for biomaterial requests for researcher's grant proposal.
TR’s FY16 bio-banking cost recovery schedule for NUHS
users only is enclosed. The cost recovery schedule does not apply to
non-NUHS, external and commercial users. Details of the fees will
be provided separately upon application.
Publications Resulting from Research on Samples from TR
12 January 2017
Wu, W., Yong, W. W., & Chung, M. C. (2016). A simple biomarker scoring matrix for early gastric cancer detection. Proteomics, 16(22), 2921-2930.
Min Thura, Abdul Qader Omer Al-Aidaroos, Wei Peng Yong, Koji Kono, Abhishek Gupta, You Bin Lin, Kousaku Mimura, Jean Paul Thiery, Boon Cher Goh, Patrick Tan, Ross Soo, Cheng William Hong, Lingzhi Wang, Suling Joyce Lin, Elya Chen, Sun Young Rha, Hyun Cheol Chung, Jie Li, Sayantani Nandi, Hiu Fung Yuen, Shu-Dong Zhang, Yeoh Khay Guan, Jimmy So and Qi Zeng (2016). PRL3-zumab, a first-in-class humanized antibody for cancer therapy. JCI Insight, 1(9), e87607.
Sun H, Lin DC, Cao Q, Guo X, Marijon H, Zhao Z, Gery S, Xu L, Yang H, Pang B, Lee V KM, Lim HJ, Doan N, Said JW, Chu P, Mayakonda A, Thomas T, Forscher C, Baloglu E, Shacham S, Rajalingam R, Koeffler HP (2016). CRM1 Inhibition Promotes Cytotoxicity in Ewing Sarcoma Cells by Repressing EWS-FLI1-Dependent IGF-1 Signaling. Cancer Research, 76(9), 2687-2697.
With immediate effect, TR would now issue a Letter of Willingness to PIs planning to use TR bio-materials/services for their research projects/study.
The Letter of Willingness, issued after prior consultation with PI, would ensure that PIs are aware of the quantity/quality and the type of biomaterials they could expect to receive from TR for their project/study. This letter would help PIs in better designing of their project/study keeping the TR numbers/type of bio-materials in mind. This would also help PIs in efficient planning of their bio-banking budget and in exploring alternate sources, if necessary, beforehand when bio-material is not available, or is in short supply in TR.
Henceforth, All PIs, planning to use TR biomaterials/services, would be required to submit this Letter of Willingness to NUS-IRB while submitting their project/study protocols for necessary IRB approvals.
Collaboration between Cardio-vascular Tissue Bank (CTVS) and TR
The Department of Cardiac, Thoracic and Vascular Surgery (CTVS), in collaboration with the TR, jointly set up the cardio-vascular tissue bank. The cardio-vascular tissue bank is expected to bank 400-500 cases a year.
TR receives IRB Approval to collect blood & other biomaterials from cancer patients at NUH
NUH Tissue Repository has recently been granted IRB approval to collect blood and other biomaterials like bone marrow, body fluids, hair, nail, saliva etc from patients at NUH.
To start with, TR would be collecting blood from cancer patients who are being selected for tissue collection and banking at TR. The blood would be collected during the patient's operative procedure in OT by the duty anaesthetist. The blood, so collected, would be frozen down into it's components viz plasma, serum, buffy coat and a part for cell immortalization purposes.TR envisages to collect around 200 to 300 blood samples from cancer patients/year.
With implementation of this service in August 2010, TR would thus, be able to provide blood and blood components, in addition to tissues, from cancer patients to biomedical researchers across Singapore.
With this IRB approval TR can now also help PI's consent, collect and store all kinds of biomaterials, such as those mentioned above, for their studies.