Immunotherapy Lab


Our group studies the cytokine receptor CD137, a member of the tumor necrosis factor receptor family. In particular, we focus on characterizing the biology of reverse signaling by CD137 ligand, which regulates the activity of hematopoietic progenitor cells and of myeloid cells and. The aim or our research is to elucidate the activities of the CD137 receptor / ligand system and to translate gained knowledge to diagnostic and therapeutic applications.