Clinical Team - Prof Jimmy So

 

Prof Jimmy So

Senior Consultant

Associate Consultant

Upper Gastrointestinal Surgery

Department of Surgery

National University Hospital

MBChB, FRCS (Edin), FRCS (Glasg), FAMS, MPH

Professional Appointments
  • Senior Consultant, Department of Surgery
  • Director, Upper GI Surgery Service
  • Director, Centre for Obesity Management & Surgery, National University Hospital, Singapore
  • Head, Division of Surgical Oncology, National University Cancer Institute of Singapore
  • Head, Upper GI Cancer Group, National University Cancer Institute of Singapore
  • Professor of Surgery, National University of Singapore
  • Associate, Cancer Institute of Singapore, National University of Singapore

Committee Memberships & Fellowship

  • International Gastric Cancer Association
  • International Society of Disease of Esophagus
  • Society of Surgery for Alimentary Tract
  • American Society of Gastrointestinal Endoscopy
  • Council member, Asia Pacific Bariatric and Metabolic Surgery Society
  • Council member, Obesity and Metabolic Surgery Society of Singapore
  • Royal College of Surgeons of Edinburgh
  • Royal College of Physicians and Surgeons of Glasgow

 

Awards

  • Best Poster Award - XVII World Congress of International Federation for the Surgery of Obesity and Metabolic Disorders, New Delhi, India, September 2012
  • “Early Outcome of Bariatric Surgery in a Multiethnic Asian Cohort”
  • Poster of Distinction- Digestive Disease Week, American Gastroenterological Association, Chicago, USA, May 2011.
  • “CD44v8-10 is a novel marker for gastric cancer stem cells”
  • James Fraser Visiting Fellow, Royal College of Surgeons of Edinburgh, UK.
  • Gold Award- NHG Doctor (NHGD) Awards, 2008 NHG ASC Scientific Paper Competition, Singapore, November 2008
  • A Prospective Randomized Crossover Study comparing Video Endoscopic Autofluorescence Imaging followed by Narrow Band imaging with Standard Endoscopy for the Detection of High Risk Lesions in stomach”
  • Best Poster Award- National Healthcare Group Annual Scientific Congress, Singapore, November 2007
  • “Profile Of Patients Attending Multi-Disciplinary Weight Management Clinic Of A Tertiary Hospital In Singapore”
  • Best Poster Presentation- 3rd International Congress of the Asia-Pacific Hernia Society, Singapore, October 2007
  • “Umbilical Hernia Repair: A Comparison Between the Laparoscopic and Conventional Techniques”
  • Best Poster Award- 6th International Gastric Cancer Congress, Yokohama, Japan, May 2005
  • “Clinical Pathway Improves Outcomes for Patients after Radical Gastrectomy for Stomach Cancer”
  • Travel Grant Award- 10th United European Gastroenterology Week, Switzerland, October 2002
  • “Anti-sense Telomerase RNA Therapy for Gastric and Colon Cancers-an in vitro study”
  • Best Poster Merit- 2002 Digestive Disease Week, San Francisco, USA, May 19th-23rd , 2002
  • “Cost-Effectiveness of Screening for Cancer of Stomach using Endoscopy”                   
  • Best Poster Merit1st NHG Scientific Congress, Singapore, 2002
  • Young Surgeon Award – at 33rd Annual Combined Surgical Meeting, Singapore, 1999
  • “Cell-cycle regulators p27 and cyclin E correlates with survival in gastric carcinoma
  • Best Free Paper Merit- 28th Annual Combined Surgical Meeting, Singapore, 1994
  • “Peritoneal infiltration of local anaesthetic in laparoscopic cholecystectomy.  A prospective study.”

Publications and Research Trials

  1. Conversion Surgery Post-Intraperitoneal Paclitaxel and Systemic Chemotherapy for Gastric Cancer Carcinomatosis Peritonei. Are We Ready? Chan DY, Syn NL, Yap R, Phua JN, Soh TI, Chee CE, Nga ME, Shabbir A, So JB, Yong WP. J Gastrointest Surg. 2016 Dec 15. PMID: 27981493
  2. Extensive peritoneal lavage after curative gastrectomy for gastric cancer (EXPEL): study protocol of an international multicentre randomised controlled trial. Kim G, Chen E, Tay AY, Lee JS, Phua JN, Shabbir A, So JB, Tai BC.
    Jpn J Clin Oncol. 2016 Nov 25. PMID: 27889694
  3. Attitudes and Concerns of Diabetic Patients towards Bariatric Surgery as Treatment of Diabetes. Chua HW, Zhou HJ, Khoo CM, Shabbir A, Lomanto D, So JB.
    Ann Acad Med Singapore. 2016 Nov;45(11):495-506. PMID: 27922143
  4. Intraperitoneal chemotherapy for gastric cancer with peritoneal disease: experience from Singapore and Japan. Kono K, Yong WP, Okayama H, Shabbir A, Momma T, Ohki S, Takenoshita S, So J. Gastric Cancer. 2016 Oct 20. [Epub ahead of print] PMID: 27766496
  5. ADAR-Mediated RNA Editing Predicts Progression and Prognosis of Gastric Cancer. Chan TH, Qamra A, Tan KT, Guo J, Yang H, Qi L, Lin JS, Ng VH, Song Y, Hong H, Tay ST, Liu Y, Lee J, Rha SY, Zhu F, So JB, Teh BT, Yeoh KG, Rozen S, Tenen DG, Tan P, Chen L. Gastroenterology. 2016 Oct;151(4):637-650.e10. doi: 10.1053/j.gastro.2016.06.043. Epub 2016 Jul 1. PMID: 27373511
  6. Accumulation of CD11c+CD163+ Adipose Tissue Macrophages through Upregulation of Intracellular 11β-HSD1 in Human Obesity. Nakajima S, Koh V, Kua LF, So J, Davide L, Lim KS, Petersen SH, Yong WP, Shabbir A, Kono K. J Immunol. 2016 Oct 3. pii: 1600895. PMID: 27698011.
  7. Is Elective Gastroscopy Prior to Bariatric Surgery in an Asian Cohort Worthwhile? Ng JY, Cheng AK, Kim G, Kong LW, Soe KT, Lomanto D, So JB, Shabbir A. Obes Surg. 2016 Sep;26(9):2156-60. doi: 10.1007/s11695-016-2060-0. PMID: 26780361  
  8. Erratum. Retinoic Acid Mediates Visceral-Specific Adipogenic Defects of Human Adipose-Derived Stem Cells. Diabetes 2016;65:1164-1178. Takeda K, Sriram S, Chan XH, Ong WK, Yeo CR, Tan B, Lee SA, Kong KV, Hoon S, Jiang H, Yuen JJ, Perumal J, Agrawal M, Vaz C, So J, Shabbir A, Blaner WS, Olivo M, Han W, Tanavde V, Toh SA, Sugii S. Diabetes. 2016 Sep;65(9):2816. doi: 10.2337/db16-er09. PMID: 27555576
  9. Phase II study of neo-adjuvant chemotherapy for locally advanced gastric cancer. Chang AY, Foo KF, Koo WH, Ong S, So J, Tan D, Lim KH. BMJ Open Gastroenterol. 2016 Aug 23;3(1):e000095. doi: 10.1136/bmjgast-2016-000095. PMID: 27648294
  10. PRL3-zumab, a first-in-class humanized antibody for cancer therapy. Thura M, Al-Aidaroos AQ, Yong WP, Kono K, Gupta A, Lin YB, Mimura K, Thiery JP, Goh BC, Tan P, Soo R, Hong CW, Wang L, Lin SJ, Chen E, Rha SY, Chung HC, Li J, Nandi S, Yuen HF, Zhang SD, Guan YK, So J, Zeng Q. JCI Insight. 2016 Jun 16;1(9):e87607. PMID: 27699276
  11. Development of an E-learning System for the Endoscopic Diagnosis of Early Gastric Cancer: An International Multicenter Randomized Controlled Trial. Yao K, Uedo N, Muto M, Ishikawa H, Cardona HJ, Filho EC, Pittayanon R, Olano C, Yao F, Parra-Blanco A, Ho SH, Avendano AG, Piscoya A, Fedorov E, Bialek AP, Mitrakov A, Caro L, Gonen C, Dolwani S, Farca A, Cuaresma LF, Bonilla JJ, Kasetsermwiriya W, Ragunath K, Kim SE, Marini M, Li H, Cimmino DG, Piskorz MM, Iacopini F, So JB, Yamazaki K, Kim GH, Ang TL, Milhomem-Cardoso DM, Waldbaum CA, Carvajal WA, Hayward CM, Singh R, Banerjee R, Anagnostopoulos GK, Takahashi Y. EBioMedicine. 2016 Jul;9:140-7. doi: 10.1016/j.ebiom.2016.05.016. PMID:27333048
  12. Retinoic Acid Mediates Visceral-Specific Adipogenic Defects of Human Adipose-Derived Stem Cells.Takeda K, Sriram S, Chan XH, Ong WK, Yeo CR, Tan B, Lee SA, Kong KV, Hoon S, Jiang H, Yuen JJ, Perumal J, Agrawal M, Vaz C, So J, Shabbir A, Blaner WS, Olivo M, Han W, Tanavde V, Toh SA, Sugii S. Diabetes. 2016 May;65(5):1164-78. doi: 10.2337/db15-1315. Epub 2016 Mar 2. Erratum in: Diabetes. 2016 Sep;65(9):2816. PMID: 26936961
  13. Investigation on the potential of Mueller matrix imaging for digital staining. Wang W, Lim LG, Srivastava S, Bok-Yan So J, Shabbir A, Liu Q. J Biophotonics. 2016 Apr;9(4):364-75. doi: 10.1002/jbio.201500006. Epub 2015 Apr 22. PMID: 25907856
  14. Melanoma associated antigen (MAGE)-A3 promotes cell proliferation and chemotherapeutic drug resistance in gastric cancer. Xie C, Subhash VV, Datta A, Liem N, Tan SH, Yeo MS, Tan WL, Koh V, Yan FL, Wong FY, Wong WK, So J, Tan IB, Padmanabhan N, Yap CT, Tan P, Goh LK, Yong WP
    Cellular Oncology (Dordrecht). 2016 Apr;39(2):175-86. doi: 10.1007/s13402-015-0261-5. Epub 2016 Feb 11. PMID: 26868260.
  15. Enterotomy closure using knotless and barbed suture in laparoscopic upper gastrointestinal   surgeries. Bautista T, Shabbir A, Rao J, So J, Kono K, Durai P. Surg Endosc. 2016 Apr;30(4):1699-703. doi: 10.1007/s00464-015-4395-3. Epub 2015 Jul 15. PMID:26173547
  16. Gelsolin-mediated activation of PI3K/Akt pathway is crucial for hepatocyte growth factor-induced cell scattering in gastric carcinoma. Huang B, Deng S, Loo SY, Datta A, Yap YL, Yan B, Ooi CH, Dinh TD, Zhuo J, Tochhawng L, Gopinadhan S, Jegadeesan T, Tan P, Salto-Tellez M, Yong WP, Soong R, Yeoh KG, Goh YC, Lobie PE, Yang H, Kumar AP, Maciver SK, So JB, Yap CT.
    Oncotarget. 2016 May 3;7(18):25391-407. doi: 10.18632/oncotarget.8603.
    PMID: 27058427
  17. Goal-directed program after sleeve gastrectomy improves weight loss. Kim G, Tan CS, Ng JY, Cheng AK, Rao J, Soe KT, Kong LW, Naseer F, Er PS, Lomanto D, So JB, Shabbir A. Surgery for Obesity and Related Diseases. 2016 Mar-Apr;12(3):518-21. doi: 10.1016/j.soard.2015.11.014. Epub 2015 Nov 19. PMID: 26944549  
  18. Inhibition of MMP activity can restore NKG2D ligand expression in gastric cancer, leading to improved NK cell susceptibility. Shiraishi K, Mimura K, Kua LF, Koh V, Siang LK, Nakajima S, Fujii H, Shabbir A, Yong WP2, So J, Takenoshita S, Kono K Journal of Gastroenterology. 2016 Mar 22. [Epub ahead of print] PMID: 27002316  
  19. Effect of weight loss after bariatric surgery on kidney function in a multiethnic Asian population. Ngoh CL, So JB, Tiong HY, Shabbir A, Teo BW. Surgery for Obesity and Related Diseases. 2016 Mar-Apr;12(3):600-5. doi: 10.1016/j.soard.2015.07.003. Epub 2015 Jul 9. PMID: 26522229
  20. Early outcomes of laparoscopic sleeve gastrectomy in a multiethnic Asian cohort. Ching SS, Cheng AK, Kong LW, Lomanto D, So JB, Shabbir A. Surgery for Obesity and  Related Diseases. 2016 Feb;12(2):330-7. doi: 10.1016/j.soard.2015.05.009. Epub 2015 May 22 PMID: 26363715
  21. Follow-up after gastrectomy for cancer: the Charter Scaligero Consensus Conference.  Baiocchi GL, D'Ugo D, Coit D, Hardwick R, Kassab P, Nashimoto A, Marrelli D, Allum W, Berruti A, Chandramohan SM, Coburn N, Gonzàlez-Moreno S, Hoelscher A, Jansen E, Leja M, Mariette C, Meyer HJ, Mönig S, Morgagni P, Ott K, Preston S, Rha SY, Roviello F, Sano T, Sasako M, Shimada H, Schuhmacher C, So Bok-Yan J, Strong V, Yoshikawa T, Terashima M, Ter-Ovanesov M, Van der Velde C, Memo M, Castelli F, Pecorelli S, Detogni C, Kodera Y, de Manzoni G. Gastric Cancer. 2016 Jan;19(1):15-20. doi: 10.1007/s10120-015-0513-0. Epub 2015 Jul 4. PMID: 26140915
  22. Submucosal carcinoma of the gastroesophageal junction diagnosed after peroral endoscopic myotomy. Chan DY, Dolgunov D, Lee VK, Chiu PW, So JB. Endoscopy. 2015;47 Suppl 1:E623-4. doi: 10.1055/s-0034-1393591. Epub 2015 Dec 29. PMID:    26714153.
  23. Computed tomography of the thorax for gastric cancer staging: is it necessary? Chong CS, Ng CW, Shabbir A, Kono K, So JB  Scandinavian Journal of Surgery. 2015 Dec;104(4):244-7. doi: 10.1177/1457496915571400.     Epub 2015 Feb 13. PMID: 25681056
  24. Removal of a large, 40-mm, submucosal leiomyoma using submucosal tunneling endoscopic resection and extraction of specimen using a distal mucosal incision. Ng JJ, Chiu PW, Shabbir A, So JB. Endoscopy. 2015;47. doi: 10.1055/s-0034-391904. Epub 2015 Jun 12. PMID: 26069978
  25. Early outcomes of laparoscopic sleeve gastrectomy in a multiethnic Asian cohort. Ching SS, Cheng AK, Kong LW, Lomanto D, So JB, Shabbir A Surgery for Obesity and Related Diseases. 2015 May 22. pii: S1550-7289(15)00152-5. doi: 10.1016/j.soard.2015.05.009. [Epub ahead of print] PMID: 26363715
  26. Recurrent Fusion Genes in Gastric Cancer: CLDN18-ARHGAP26 Induces Loss of Epithelial Integrity Fei Yao, Jaya P. Kausalya, Yee Yen Sia, Audrey S.M. Teo, Wah Heng Lee, Alicia G.M. Ong,    Zhenshui Zhang, Joanna H.J. Tan, Guoliang Li, Denis Bertrand, Xingliang Liu, Huay Mei Poh, Peiyong Guan, Feng Zhu, Thushangi Nadeera Pathiraja, Pramila N. Ariyaratne, Jaideepraj Rao, Xing Yi Woo, Shaojiang Cai, Fabianus H. Mulawadi, Wan Ting Poh, Lavanya Veeravalli, Chee Seng Chan, Seong Soo Lim, See Ting Leong, Say Chuan Neo, Poh Sum D. Choi, Elaine G.Y. Chew, Niranjan Nagarajan, Pierre-E´ tienne Jacques, Jimmy B.Y. So, Xiaoan Ruan, Khay Guan Yeoh, Patrick Tan, Wing-Kin Sung, Walter Hunziker, Yijun Ruan, Axel M. Hillmer.  Cell Report. 2015 Jul 14;12:1-14 PMID: 26146084
  27. Rare & Special Cases. Light D, Griffin M, Srivastava K, Danelli P, Ballerini A, Leone N, Bondurri A, Khare R, Shabbir A, Wijerathne S, So JB, Clara E, Tang SW, Tan WB, Hu J, Lomanto D, Ji Z, Li J, East B, Pazdirek F, Hoch J, Ji ZL, Malik D, Reddy P, Sahu D, Forgione U, Gianatiempo M, Xiong M, Chen B, Zhang JW, Li T, Luo XG, Li Q, Yu X, Zhao XD, Chen HY, Sun FX, Feng GZ, Zhang JP, Yu CZ, Aboulwafa A, Mahfouz A, Khairat M, Althani H, Albosoum E, Alebrahim H. Hernia. 2015 Apr;19 Suppl 1:S19-24. doi: 10.1007/BF03355321. PMID: 26518798 
  28. Longer examination time improves detection of gastric cancer during diagnostic upper gastrointestinal endoscopy. Teh JL, Tan JR2, Lau LJ, Saxena N, Salim A, Tay A, Shabbir A, Chung S, Hartman M,  Bok-Yan So J. Clinical Gastroenterology and Hepatology. 2015 Mar;13(3):480-487. PMID: 25117772
  29. Diagnosis and treatment of Helicobacter pylori for peptic ulcer bleeding in clinical practice - factors associated with non-diagnosis and non-treatment, and diagnostic yield in various settings.  Lim LG, Ho KY, So JB, Khor CJ, Lim LL, Teoh PL, Yeoh KG. Turk J Gastroenterol. 2014 Dec;25 Suppl 1:157-61. doi: 10.5152/tjg.2014.3843. PMID: 25910297
  30. Signatures of tumour immunity distinguish Asian and non-Asian gastric adenocarcinomas. Lin SJ, Gagnon-Bartsch JA, Tan IB, Earle S, Ruff L, Pettinger K, Ylstra B, van Grieken N, Rha SY, Chung     HC, Lee JS, Cheong JH, Noh SH, Aoyama T, Miyagi Y, Tsuburaya A, Yoshikawa T, Ajani JA, Boussioutas A, Yeoh KG, Yong WP, So J, Lee J, Kang WK, Kim S, Kameda Y, Arai T, Zur Hausen A, Speed TP, Grabsch HI, Tan P. Gut. 2014 Nov 10. pii: gutjnl-2014-308252. PMID: 25385008
  31. Inhibition of mitogen-activated protein kinase (MAPK) pathway can induce upregulation of human leukocyte antigen class I without PD-L1-upregulation in contrast to interferon-γ treatment. Mimura K, Kua LF, Shiraishi K, Kee Siang L, Shabbir A, Komachi M, Suzuki Y, Nakano T, Yong WP, So J, Kono K. Cancer Science. 2014 Oct;105(10):1236-44 PMID: 25154680
  32. CT volumetry for gastric carcinoma: association with TNM stage. Hallinan JT, Venkatesh SK, Peter L, Makmur A, Yong WP, So JB. European Radiology. 2014 Dec;24(12):3105-14 PMID: 25038858
  33. Implications of morbid obesity and surgery for the obese. Loo LM, Shabbir A, So JB. Annals Academy of Medicine Singapore. 2014 Jun;43(6):328-30 PMID: 25028143
  34. Roles of linear and circular polarization properties and effect of wavelength choice on differentiation between ex vivo normal and cancerous gastric samples. Wang W, Lim LG, Srivastava S, Yan JS, Shabbir A, Liu Q. Journal of Biomedical Optics. 2014 Apr;19(4):046020 PMID: 24781588
  35. CD44v8-10 is a cancer-specific marker for gastric cancer stem cells. Lau WM, Teng E, Chong HS, Lopez KA, Tay AY, Salto-Tellez M, Shabbir A, So JB, Chan SL. Cancer Research. 2014 May 1;74(9):2630-41 PMID: 24618343
  36. Therapeutic potential of highly cytotoxic natural killer cells for gastric cancer. Mimura K, Kamiya T, Shiraishi K, Kua LF, Shabbir A, So J, Yong WP, Suzuki Y, Yoshimoto Y, Nakano T, Fujii H, Campana D, Kono K.
    International Journal of Cancer. 2014 Sep 15;135(6):1390-8. PMID: 24615495
  37. Identification of specific cell-surface markers of adipose-derived stem cells from subcutaneous and visceral fat depots. Ong WK, Tan CS, Chan KL, Goesantoso GG, Chan XH, Chan E, Yin J, Yeo CR, Khoo CM, So JB, Shabbir A, Toh SA, Han W, Sugii S. Stem Cell Reports. 2014 Feb 6; 2(2):171-9. eCollection. PMID: 24527391.
  38. Fiberoptic Confocal Raman Spectroscopy for Real-Time In Vivo Diagnosis of Dysplasia in Barrett's Esophagus. Bergholt MS, Zheng W, Ho KY, Teh M, Yeoh KG, Yan So JB, Shabbir A, Huang Z.Gastroenterology. 2014 Jan; 146(1):27-32 PMID: 2421637
  39. The MAPK pathway is a predominant regulator of HLA-A expression in esophageal and gastric cancer. Mimura K, Shiraishi K, Mueller A, Izawa S, Kua LF, So J, Yong WP, Fujii H, Seliger B, Kiessling R, Kono K. Journal of Immunology. 2013 Dec 15;191(12):6261-72. PMID: 24244023
  40. Endoscopic tri-modal imaging improves detection of gastric intestinal metaplasia among a high-risk patient population in Singapore. So J, Rajnakova A, Chan YH, Tay A, Shah N, Salto-Tellez M, Teh M, Uedo Noriya. Digestive Diseases and Sciences. 2013 Dec; 58(12):3566-75. PMID: 23996468
  41. Tbx2a is required for specification of endodermal pouches during development of the pharyngeal arches.Thi Thu HN, Haw Tien SF, Loh SL, Bok Yan JS, Korzh V. PLoS One. 2013 Oct 10;8(10):e77171. eCollection 2013. PMID: 24130849
  42. Single-port endo-laparoscopic surgery in combined abdominal procedures. Kim G, Lomanto D, Lawenko MM, Lopez-Gutierrez J, Lee-Ong A, Iyer SG, Cheah WK, So JB, Tsang CB, Fong YF.Asian Journal of Endoscopic Surgery. 2013 Aug;6(3):209-13. PMID: 23879412
  43. Identification of molecular subtypes of gastric cancer with different responses to PI3-kinase inhibitors and 5-fluorouracil. Lei Z, Tan IB, Das K, Deng N, Zouridis H, Pattison S, Chua C, Feng Z, Guan YK, Ooi CH, Ivanova T, Zhang S, Lee M, Wu J, Ngo A, Manesh S, Tan E, Teh BT, So JB, Goh LK, Boussioutas A, Lim TK, Flotow H, Tan P, Rozen SG. Gastroenterology. 2013 Sep;145(3):554-65. PMID: 23684942
  44. Perforated early gastric cancer: uncommon and easily missed a case report and review of literature. Lim RH, Tay CM, Wong B, Chong CS, Kono K, So JB, Shabbir A. Journal of Gastric Cancer. 2013 Mar;13(1):65-8. PMID: 23610721
  45. Muco-submucosal elongated polyps of the gastrointestinal tract: a case series and a review of the literature.Tan CL, Tan SH, So JB, Petersson F. World Journal of Gastroenterology. 2013 Mar 21;19(11):1845-9. Review. PMID: 23555175 
  46. Fiber-optic Raman spectroscopy probes gastric carcinogenesis in vivo at endoscopy. Bergholt MS, Zheng W, Ho KY, Teh M, Yeoh KG, So JB, Shabbir A, Huang Z. Journal of Biophotonics. 2013 Jan;6(1):49-59 PMID: 23288709
  47. Bariatric surgery in Singapore from 2005 to 2009. Goel R, Agarwal A, Shabbir A, So JB, Pasupathy S, Wong A, Cheng A, Lomanto D.Asian Journal of Surgery. 2013 Jan;36(1):36-9 PMID: 23270823 Potential therapeutic significance of HER-family in esophageal squamous cell carcinoma. Kono K, Mimura K, Fujii H, Shabbir A, Yong WP, Jimmy So A. Annals of Thoracic & Cardiovascular Surgery. 2012;18(6):506-13. PMID: 23270823
  48. Real-time Raman spectroscopy for in vivo, online gastric cancer diagnosis during clinical endoscopic examination. Duraipandian S, Sylvest Bergholt M, Zheng W, Yu Ho K, Teh M, Guan Yeoh K, Bok Yan So J, Shabbir A, Huang Z. Journal of Biomedical Optics. 2012 Aug;17(8):081418  PMID: 23224179
  49. Whole-genome reconstruction and mutational signatures in gastric cancer. Nagarajan N, Bertrand D, Hillmer AM, Zang ZJ, Yao F, Jacques PÉ, Teo AS, Cutcutache I, Zhang Z, Lee WH, Sia YY, Gao S, Ariyaratne PN, Ho A, Woo XY, Veeravali L, Ong CK, Deng N, Desai KV, Khor CC, Hibberd ML, Shahab A, Rao J, Wu M, Teh M, Zhu F, Chin SY, Pang B, So JB, Bourque G, Soong R, Sung WK, Tean Teh B, Rozen S, Ruan X, Yeoh KG, Tan PB, Ruan Y. Genome Biology. 2012 Dec 13;13(12):R115 PMID: 23237666
  50. Validation of the functional assessment of cancer therapy-gastric module for the Chinese population. Zhou HJ, So JB, Yong WP, Luo N, Zhu F, Naidoo N, Li SC, Yeoh KG.Health and Quality of Life Outcomes. 2012 Nov 30;10:145. PMID: 23194009
  51. Bariatric surgery in Asia in the last 5 years (2005-2009). Lomanto D, Lee WJ, Goel R, Lee JJ, Shabbir A, So JB, Huang CK, Chowbey P, Lakdawala M, Sutedja B, Wong SK, Kitano S, Chin KF, Dineros HC, Wong A, Cheng A, Pasupathy S, Lee SK, Pongchairerks P, Giang TB. Obes Surg. 2012 Mar;22(3):502-6. doi: 10.1007/s11695-011-0547-2. Review. Erratum in: Obes Surg. 2012 Feb;22(2):345. Fah, Chin Kin [corrected to Chin, Kin-Fah]. PMID: 22033767
  52. Laparoscopic excision of intrathoracic oesophageal duplication cyst in a Singaporean adult male. Lu J, Loo LM, So JB, Shabbir A. Annals Academy of Medicine Singapore. 2012 Mar;41(3):129-31 PMID: 22538741
  53. S100A9, GIF and AAT as potential combinatorial biomarkers in gastric cancer diagnosis and prognosis. Wu W, Juan WC, Liang CR, Yeoh KG, So J, Chung MC. Proteomics Clinical Applications. 2012 Apr;6(3-4):152-62 PMID: 22532451
  54. Exome sequencing of gastric adenocarcinoma identifies recurrent somatic mutations in cell adhesion and chromatin remodeling genes. Zang ZJ, Cutcutache I, Poon SL, Zhang SL, McPherson JR, Tao J, Rajasegaran V, Heng HL, Deng N, Gan A, Lim KH, Ong CK, Huang D, Chin SY, Tan IB, Ng CC, Yu W, Wu Y, Lee M, Wu J, Poh D, Wan WK, Rha SY, So J, Salto-Tellez M, Yeoh KG, Wong WK, Zhu YJ, Futreal PA, Pang B, Ruan Y, Hillmer AM, Bertrand D, Nagarajan N, Rozen S, Teh BT, Tan P. Nature Genetics. 2012 May;44(5):570-4 PMID: 22484628
  55. Connection tubing causing small bowel obstruction and colonic erosion as a rare complication after laparoscopic gastric banding: a case report. Tan LB, So JB, Shabbir A. Journal of Medical Case Reports. 2012 Jan 11;6:9. PMID: 22236382
  56. Mining the gastric cancer secretome: identification of GRN as a potential diagnostic marker for early gastric cancer. Loei H, Tan HT, Lim TK, Lim KH, So JB, Yeoh KG, Chung MC. Journal of Proteome Research. 2012 Mar 2;11(3):1759-72. PMID: 22204653
  57. Suspected oesophageal cancer in a 33 year old lady. Tay CW, Deans DA, Khor JL, Seet JE, So BY. International Journal of Surgery Case Reports. 2011; 2(2):13-5.   PMID: 22096676
  58. Bariatric surgery in Asia in the last 5 years (2005-2009). Lomanto D, Lee WJ, Goel R, Lee JJ, Shabbir A, So JB, Huang CK, Chowbey P, Lakdawala M, Sutedja B, Wong SK, Kitano S, Chin Kin-Fah, Dineros HC, Wong A, Cheng A, Pasupathy S, Lee SK, Pongchairerks P, Giang TB. Obesity Surgery. 2012 Mar;22(3):502-6. Review. PMID: 22033767
  59. Intrinsic subtypes of gastric cancer, based on gene expression pattern, predict survival and respond differently to chemotherapy. Tan IB, Ivanova T, Lim KH, Ong CW, Deng N, Lee J, Tan SH, Wu J, Lee MH, Ooi CH, Rha SY, Wong WK, Boussioutas A, Yeoh KG, So J, Yong WP, Tsuburaya A, Grabsch H, Toh HC, Rozen S, Cheong JH, Noh SH, Wan WK, Ajani JA, Lee JS, Tellez MS, Tan P. Gastroenterology. 2011 Aug;141(2):476-85, 485.e1-11.
  60. Combining near-infrared-excited autofluorescence and Raman spectroscopy improves in vivo diagnosis of gastric cancer. Bergholt MS, Zheng W, Lin K, Ho KY, Teh M, Yeoh KG, So JB, Huang Z. Biosensors & Bioelectronics. 2011 Jun 15;26(10):4104-10. PMID: 21550225
  61. Experienced versus inexperienced confocal endoscopists in the diagnosis of gastric adenocarcinoma and intestinal metaplasia on confocal images. Lim LG, Yeoh KG, Salto-Tellez M, Khor CJ, Teh M, Chan YH, So JB, Rajnakova A, Shen E, Srivastava S, Ho KY. Gastrointestinal Endoscopy. 2011 Jun;73(6):1141-7 PMID: 21492850
  62. Pseudodiverticulosis of the gastroesophageal junction mimicking a carcinoma. Mantoo SK, So J, Shabbir A, Sun LY. Gastrointestinal Endoscopy. 2011 Jun;73(6):1280-1 In vivo diagnosis of gastric cancer using raman endoscopy and ant colony optimization techniques. Bergholt MS, Zheng W, Lin K, Ho KY, Teh M, Yeoh KG, So JBY, Huang Z.International Journal of Cancer 2011 Jun 1;128(11):2673-80. PMID: 21354566
  63. Comprehensive long-span paired-end-tag mapping reveals characteristic patterns of structural variations in epithelial cancer genomes. Hillmer AM, Yao F, Inaki K, Lee WH, Ariyaratne PN, Teo AS, Woo XY, Zhang Z, Zhao H, Ukil L, Chen JP, Zhu F, So JB, Salto-Tellez M, Poh WT, Zawack KF, Nagarajan N, Gao S, Li G, Kumar V, Lim HP, Sia YY, Chan CS, Leong ST, Neo SC, Choi PS, Thoreau H, Tan PB, Shahab A, Ruan X, Bergh J, Hall P, Cacheux-Rataboul V, Wei CL, Yeoh KG, Sung WK, Bourque G, Liu ET, Ruan Y. Genome Research. 2011 May;21(5):665-75.  PMID: 21467267
  64. Characterizing variability in in vivo Raman spectra of different anatomical locations in the upper gastrointestinal tract toward cancer detection. Bergholt MS, Zheng W, Lin K, Ho KY, Teh M, Yeoh KG, So JB, Huang Z.Journal of Biomedical Optics. 2011 Mar;16(3):037003. PMID: 21456876
  65. Closure of gastrotomy in natural orifice transluminal endoscopic surgery: a feasibility study using an ex vivo model comparing endoloop with endoclip. Shabbir A, Liang S, Lomanto D, Ho KY, So JB.Digestive Endoscopy 2011 Apr;23(2):130-4.  PMID: 21429017
  66. In vivo diagnosis of esophageal cancer using image-guided Raman endoscopy and biomolecular modeling. Bergholt MS, Zheng W, Lin K, Ho KY, Teh M, Yeoh KG, So JB, Huang Z. Technology in Cancer Research & Treatment. 2011 Apr;10(2):103-12 PMID: 21381788
  67. Cancer of the gastric cardia is rising in incidence in an Asian population and is associated with adverse outcome. Deans C, Yeo MS, Soe MY, Shabbir A, Ti TK, So JB. World Journal of Surgery. 2011 Mar;35(3):617-24 PMID: 21203759
  68. Raman endoscopy for in vivo differentiation between benign and malignant ulcers in the stomach.Bergholt MS, Zheng W, Lin K, Ho KY, Teh M, Yeoh KG, So JB, Huang Z. Analyst. 2010 Dec;135(12):3162-8. PMID: 20941419
  69. Proteomic analysis of human gastric juice: a shotgun approach. Liang CR, Tan S, Tan HT, Lin Q, Lim TK, Liu Y, Yeoh KG, So J, Chung MC. Proteomics. 2010 Nov;10(21):3928-31 PMID: 20925057
  70. Upregulation of plasma C9 protein in gastric cancer patients. Chong PK, Lee H, Loh MC, Choong LY, Lin Q, So JB, Lim KH, Soo RA, Yong WP, Chan SP, Smoot DT, Ashktorab H, Yeoh KG, Lim YP. Proteomics. 2010 Sep;10(18):3210-21 PMID: 20707004
  71. Endoscopic submucosal dissection of gastric lesions by using a Master and Slave Transluminal Endoscopic Robot (MASTER). Ho KY, Phee SJ, Shabbir A, Low SC, Huynh VA, Kencana AP, Yang K, Lomanto D, So BY, Wong YY, Chung SC. Gastrointestinal Endoscopy. 2010 Sep;72(3):593-9. PMID: 20646698
  72. ITIH3 is a potential biomarker for early detection of gastric cancer. Chong PK, Lee H, Zhou J, Liu SC, Loh MC, Wang TT, Chan SP, Smoot DT, Ashktorab H, So JB, Lim KH, Yeoh KG, Lim YP. Journal of Proteome Research. 2010 Jul 2;9(7):3671-9. PMID: 20515073
  73. Reduced plasma APOA1 level is associated with gastric tumor growth in MKN45 mouse xenograft model. Chong PK, Lee H, Zhou J, Liu SC, Loh MC, So JB, Lim KH, Yeoh KG, Lim YP. Journal of Proteomics. 2010 Jun 16;73(8):1632-40. PMID: 20399916
  74. Surgical management of obesity - National University Hospital experience.Shabbir A, Loi TH, Lomanto D, Ti TK, So JB. Annals Academy of Medicine Singapore. 2009 Oct;38(10):882-90 PMID: 19890580
  75. Genetic factors associated with intestinal metaplasia in a high risk Singapore-Chinese population: a cohort study. Zhu F, Loh M, Hill J, Lee S, Koh KX, Lai KW, Salto-Tellez M, Iacopetta B, Yeoh KG, Soong R; Singapore Gastric Cancer Consortium. BMC Gastroenterology. 2009 Oct 13;9:76. PMID: 19822020
  76. Oncogenic pathway combinations predict clinical prognosis in gastric cancer. Ooi CH, Ivanova T, Wu J, Lee M, Tan IB, Tao J, Ward L, Koo JH, Gopalakrishnan V, Zhu Y, Cheng LL, Lee J, Rha SY, Chung HC, Ganesan K, So J, Soo KC, Lim D, Chan WH, Wong WK, Bowtell D, Yeoh KG, Grabsch H, Boussioutas A, Tan P. PLoS Genetics. 2009 Oct;5(10):e1000676. PMID: 19798449
  77. Laparoscopic appendectomy by residents: evaluating outcomes and learning curve. Lin YY, Shabbir A, So JB. Surgical Endoscopy. 2010 Jan;24(1):125-30 Prognosticating gastric cancer.So JB, Yeoh KG. Journal of Gastroenterology and Hepatology. 2009 Sep;24(9):1478-9. PMID: 19760332
  78. Microbiological contamination during transgastric and transvaginal endoscopic techniques. Lomanto D, Chua HC, Myat MM, So J, Shabbir A, Ho L. Journal of Laparoendoscopic & Advanced Surgical Techniques. 2009 Aug;19(4):465-9. PMID: 19575634
  79. Gastric adenocarcinoma occurring in a young patient with common variable immunodeficiency syndrome. Yap YL, So JB. Singapore Medical Journal. 2009 Jun;50(6):e201-3. PMID: 19551296
  80. Total transvaginal endoscopic abdominal wall hernia repair: a NOTES survival study.Lomanto D, Dhir U, So JB, Cheah WK, Moe MA, Ho KY. Hernia. 2009 Aug;13(4):415-9. PMID: 19242774
  81. Confronting the obesity epidemic: call to arms. Lee YS, So JB, Deurenberg-Yap M. Annals Academy of Medicine Singapore. 2009 Jan;38(1):1-2. PMID: 19221663
  82. Outcomes of adjuvant chemoradiotherapy after a radical gastrectomy and a D2 node dissection for gastric adenocarcinoma. Leong CN, Chung HT, Lee KM, Shakespeare TP, Mukherjee RK, Wong LC, Lu JJ, Tey J, Lim R, So JB, Back MF. Cancer Journal. 2008 Jul-Aug;14(4):269-75. PMID: 18677137
  83. Reduction of hospital stay and cost after the implementation of a clinical pathway for radical gastrectomy for gastric cancer. So JB, Lim ZL, Lin HA, Ti TK.  Gastric Cancer. 2008 Jun;11(2):81-5. PMID: 18595014
  84. Diagnostic laparoscopy in the evaluation of right lower abdominal pain: a one-year audit. Lim GH, Shabbir A, So JB. Singapore Medical Journal. 2008 Jun;49(6):451-3.  PMID: 18581015
  85. Value of intensive follow-up of patients after curative surgery for gastric carcinoma. Tan IT, So BY. Journal of Surgical Oncology. 2007 Nov 1;96(6):503-6. PMID: 17680634
  86. Gastrointestinal fluids proteomics. Tan S, Liang CR, Yeoh KG, So J, Hew CL, Chung MC. Proteomics Clinical Applications. 2007 Aug;1(8):820-33. PMID: 21136736
  87. Intramural tracking in esophageal pseudodiverticulosis. Wang E, Tang A, Venkatesh S, So J. Endoscopy. 2007 Feb;39 Supplement 1:E265-6. PMID: 17957608
  88. Traumatic Abdominal Wall Hernia: Open and Laparoscopic Approaches To Repair. HY Tiong, JBY So, WK  Cheah. The Internet Journal of Surgery 2007:10(2) (online article)
  89. A report on the First Asia-Pacific Gastric Cancer Conference. Sudirman A, Gan E, So JB. Gastric Cancer. 2007 Jun;10(2):140-4. PMID: 17577626
  90. Comparing T2 and T2-T3 ablation in thoracoscopic sympathectomy for palmar hyperhidrosis: a randomized control trial.  Katara AN, Domino JP, Cheah WK, So JB, Ning C, Lomanto D. Surgical Endoscopy. 2007 Oct;21(10):1768-71. PMID: 17404794
  91. Role of Endoscopic Ultrasound in Management of Gastric Cancer. S Iyer, So JBY, Ho KY. Surgical Endoscopy 2006;20:559-62
  92. Endoscopic screening for gastric cancer. Dan YY, So JB, Yeoh KG. Clinical Gastroenterology and Hepatology. 2006 Jun;4(6):709-16.
  93. Endoscopic ultrasonography for gastric cancer: does it influence treatment? Ganpathi IS, So JB, Ho KY. Surgical Endoscopy. 2006 Apr;20(4):559-62. PMID: 16446988
  94. Detection of telomerase activity in gastric lavage fluid: a novel method to detect gastric cancer. Wong SC, Yu H, So JB. Journal of Surgical Research. 2006 Apr;131(2):252-5.
  95. Periampullary diverticulum: a case of bleeding from a periampullary diverticulum. Kua JE, Seah A, So JB. Annals Academy of Medicine Singapore. 2005 Nov;34(10):636-8. PMID: 16382250
  96. Endoscopic extraperitoneal inguinal hernia repair: a series of 182 repairs. PMID: 15181520 Cheah WK, So JB, Lomanto D. Singapore Medical Journal. 2004 Jun;45(6):267-70
  97. Cloning of rat telomerase catalytic subunit functional domains, reconstitution of telomerase activity and enzymatic profile of pig and chicken tissues. Wong SC, Ong LL, Er CP, Gao S, Yu H, So JB. Life Sciences2003 Oct 10;73(21):2749-60. PMID: 13679242
  98. Antisense telomerase induced cell growth inhibition, cell cycle arrest and telomerase activity down-regulation in gastric and colon cancer cells. Wong SC, Yu H, Moochhala SM, So JB. Anticancer Research. 2003 Jan-Feb;23(1A):465-9. PMID: 12680250
  99. Serum pepsinogen levels in gastric cancer patients and their relationship with Helicobacter pylori infection: a prospective study. So JB, Yeoh KG, Moochala S, Chachlani N, Ho J, Wong WK, Mack P, Goh PM. Gastric Cancer. 2002;5(4):228-32. PMID: 12491081
  100. Routine use of setons for the treatment of anal fistulae. Theerapol A, So BY, Ngoi SS. Singapore Medical Journal. 2002 Jun;43(6):305-7 PMID: 12380728
  101. Laparoscopic appendectomy for perforated appendicitis. So JB, Chiong EC, Chiong E, Cheah WK, Lomanto D, Goh P, Kum CK. World Journal of Surgery. 2002 Dec;26(12):1485-8
  102. Ondansetron in the prevention of postoperative nausea and vomiting after laparoscopic cholecystectomy: a prospective randomized study. So JB, Cheong KF, Sng C, Cheah WK, Goh P. Surgical Endoscopy. 2002 Feb;16(2):286-8
  103. Robotic-assisted laparoscopic cholecystectomy. Goh PM, Lomanto D, So JB. Surgical Endoscopy. 2002 Jan;16(1):216-7
  104. The Current Status of Laparoscopic Resection for Gastric Cancer. So JBY, Goh P.Asian Journal of Surgery 2001; 24:248-51
  105. Robotically assisted laparoscopic cholecystectomy: a pilot study. Lomanto D, Cheah WK, So JB, Goh PM. Archives of Surgery. 2001 Oct;136(10):1106-8. PMID: 11585499
  106. Use of laparoscopy in the management of mesenteric venous thrombosis. Chong AK, So JB, Ti TK. Surgical Endoscopy. 2001 Sep;15(9):1042.
  107. Evaluation of a head-mounted display (HMD) in the Performance of a Simulated Laproscopic Task.  Cheah WK, Lenzi JE, So J, Dong F, Kum CK, Goh P.   Surgical Endoscopy 2001 Sep;15(9): 990-1 PMID: 11443461
  108. Two-trocar laparoscopic cholecystectomy: a reproducible technique.  Lomanto D, De Angelis L, Ceci V, Dalsasso G, So J, Frattaroli FM, Muthiah  R, Speranza V. Surgical Laparoscopy, Endoscopy & Percutaneous Techniques 2001 Aug;11(4): 248-51
  109. Thoracolaparoscopic repair of traumatic diaphragmatic rupture.Lomanto D, Poon PL, So JB, Sim EW, El Oakley R, Goh PM. Surgical Endoscopy. 2001 Mar;15(3):323. PMID: 11344439
  110. Early experience with laparoscopic radical gastrectomy for advanced gastric cancer. Goh PM, Khan AZ, So JB, Lomanto D, Cheah WK, Muthiah R, Gandhi A. Surgical Laparoscopic Endoscopy & Percutaneous Techniques. 2001 Apr;11(2):83-7. PMID: 11330389
  111. Clinical and Pathological features of Early Gastric Cancer in Singapore. So JBY, Samarasinge K, Gangaraju CR, Ti TK. Annals of the College of Surgeons of Hong Kong (nka Surgical Practice) 2001 Feb;5(1):10-13
  112. Randomized trial of needlescopic versus laparoscopic cholecystectomy. Cheah WK, Lenzi JE, So JB, Kum CK, Goh PM. British Journal of Surgery. 2001 Jan;88(1):45-7. PMID: 11136308
  113. Risk factors related to operative mortality and morbidity in patients undergoing emergency gastrectomy. So JB, Yam A, Cheah WK, Kum CK, Goh PM.British Journal of Surgery. 2000 Dec;87(12):1702-7.  PMID: 11122188
  114. Expression of cell-cycle regulators p27 and cyclin E correlates with survival in gastric carcinoma patients. So JB, Samarasinge K, Raju GC, Moochhala SM, Ti TK. Journal of Surgical Research. 2000 Nov; 94(1):56-60. PMID: 11038303
  115. Role of laparoscopy in the management of stomach cancer. Goh PM, So JB.Seminars in Surgical Oncology. 1999 Jun;16(4):321-6. Review.  PMID: 10332778
  116. Duodenal Ulcer Perforation following Cyanoacrylate Injection.  Cheah WK, So JBY, SM Chong, Goh PMY. Endoscopy 2000 May; 32(5):S23. PMID: 10817190
  117. Bleeding Right Colon Diverticular Disease. So JBY, Kok K, Ngoi SS. American Surgeon 1999; 65:321-25
  118. Right-sided colonic diverticular disease as a source of lower gastrointestinal bleeding. So JB, Kok K, Ngoi SS. American Surgeon. 1999 Apr;65(4):299-302. PMID: 10190349
  119. Experience of percutaneous endoscopic gastrostomy at Massachusetts General Hospital--indications and complications. So JB, Ackroyd FW. Singapore Medical Journal. 1998 Dec;39(12):560-3. PMID: 10067402
  120. Outcomes of atypical symptoms attributed to gastroesophageal reflux treated by laparoscopic fundoplication. So JB, Zeitels SM, Rattner DW. Surgery. 1998 Jul;124(1):28-32.  PMID: 9663248
  121. Postoperative perineal hernia. So JB, Palmer MT, Shellito PC. Diseases of the Colon & Rectum. 1997 Aug;40(8):954-7
  122. A study of the effects of bowel preparation on CEA levels in patients undergoing surveillance colonoscopy. So JB, Alexander DJ, Chia YW, Ngoi SS, Lee L, Goh PM. Journal of the Royal College of Surgeons of Edinburgh. 1997 Apr;42(2):105-6. PMID: 9114681
  123. Comparison between laparoscopic and conventional omental patch repair for perforated duodenal ulcer. So JB, Kum CK, Fernandes ML, Goh P. Surgical Endoscopy. 1996 Nov;10(11):1060-3. PMID: 8881052
  124. Needlescopic Retrograde Cholecystectomy.  Cheah WK, Goh PMY, Gagner M, So JBY. Surgical Laparoscopy & Endoscopy 1998 Jun; 8(3):237-238 PMID: 9649052
  125. A study of the effects of bowel preparation on CEA levels in patients undergoing surveillance colonoscopy. So JB, Alexander DJ, Chia YW, Ngoi SS, Lee L, Goh PM. Journal of the Royal College of Surgeons of Edinburgh. 1997 Apr;42(2):105-6. PMID: 9114681
  126. Randomized trial of periportal peritoneal bupivacaine for pain relief after laparoscopic cholecystectomy. Alexander DJ, Ngoi SS, Lee L, So J, Mak K, Chan S, Goh PM.  British Journal of Surgery. 1996 Sep;83(9):1223-5. PMID: 8983611
  127. Laparoscopic appendicectomy in the management of acute lower gastrointestinal bleeding. So JB, Alexander DJ, Chong AP, Goh PM. Gastrointestinal Endoscopy. 1995 Nov;42(5):488-9. PMID: 8566644