Research Staff


Junhong

"I’m involving in the Cryosphere Project in collaboration with DSO National Laboratories. This project is about platelets freezing. The goal is to increase platelets stockpile. My job areas are optimization of a human platelet freezing procedure and set up and optimize a new panel of plasma and platelet quality control assays."

(PI: A/P Dheen ST)


Aparna

"Microglia, the scavenger cells of the brain, are found in brain tumors and support the growth of the tumor. My project focuses on understanding molecular and epigenetic mechanisms that regulate microglial behaviour in tumors. This will lay the foundation for designing microglia-centric therapeutic strategies to treat brain tumors."

(PI: A/P Dheen ST)

Neelima

"Studying the Molecular and Epigenetic mechanisms underlying the Tumor-supportive phenotypes of Glioma-associated Microglia (GAMs) to understand the pathways which may switch the GAMs back to tumor suppressive phenotype for management of tumor progression."

(PI: A/P Dheen ST)


Ashwini

"My research work involves the study of the molecular and epigenetic mechanisms regulating tumor supportive behaviour of microglia in Glioma, a malignant brain tumor."

(PI: A/P Dheen ST)


Simbu

"Human Neuronal stem/Progenitors cells (hNSCs/hNPCs) are powerful research tool to address various neurodegenerative diseases (Alzheimer, dementia and microcephaly). My research interest is to understand and unleash the novel regulation of epigenetic changes (DNA methylation) as well as the role of non-coding RNAs (miRNAs and LncRNAs) during the neuropathological disease conditions."

(PI: A/P Dheen ST)


Sukanya

"My research focuses on identifying the molecular and epigenetic mechanisms underlying neurodevelopmental disorders associated with maternal diabetes/ viral infection during pregnancy. This study will provide mechanistic insights into the etiology of neurodevelopmental disorders and identify potential molecular candidates for therapeutic intervention. "

(PI: A/P Dheen ST)


Hariharan

"My areas of interests are regenerative medicine and cancer biology. my current research is focused on skin tissue engineering by fabricating a bio-compatible scaffolds by incorporating bio-active protein, TGF-β  for the application of diabetic wound healing."

(PI: A/P Dinesh)


Max Kosok

"Max Kosok is developing mass spectrometry based proteomics strategies to study cancer regulation for therapeutics. He is focusing on breast cancer with special interest in the triple negative subtype."

(PI: Prof Bay BH)


Cheng Teng

"Ng Cheng Teng's research interests focus on potential impacts of engineered nanomaterials on the environment and biological systems."

(PI: Prof Bay Boon Huat)


Valerie

“Phyllodes tumours (PTs) of the breast are uncommon fibroepithelial neoplasms comprising <1.0% of all breast tumours. Most PTs are benign; however, malignant PTs can behave aggressively by metastasizing to distant organs. The prognosis of patients with metastasis is dismal with high mortality rates. We aim to investigate the expression of biomarkers and their clinical significance in women with malignant PTs.”

(PI: Prof Bay Boon Huat)


Rita

"The interplay between hypoxic microenvironment, bone loss and inflammatory mediators in periprosthetic tissues from failed hip and knee joint replacements are being examined by histological and molecular techniques. Also the role of the inflammasome is being investigated."

(PI: Prof Charanjit Kaur)


Dhiraj

"Cellular and molecular mechanisms underlying periventricular white matter damage in the developing brain."

(PI: Prof Charanjit Kaur)


Xing Fei

"Investigation into the roles of glycosaminoglycans (GAG) and proteoglycans (PG) in breast, bladder and other cancer types. Transcriptomics and proteomics approaches are used to elucidate GAG-mediated signaling pathways that regulate tumor progression."

(PI: A/Prof George Yip)


Wei Xuan

"Carbohydrates known as glycosaminoglycans (GAGs) were once thought as energy storage molecules. Recently however, they have been shown to affect cell properties and functions, thereby playing important roles in physiological and pathological conditions. Using a combination of molecular biology and immunohistochemistry, I aim to elucidate the pathological role of GAGs and their associated proteins known as proteoglycans in breast cancer."

(PI: A/Prof George Yip)

Hue San

"Glycosaminoglycans and proteoglycans have major roles in multiple cancer-related processes. My research interest is to study their downstream effectors and to determine if they can be utilised as cancer biomarkers and therapeutic targets."

(PI: A/Prof George Yip)

Charannya

"Role of non-coding RNAs (ncRNA) in various biological processes remain largely unexplored. My research interest is to examine the function of ncRNAs especially piRNAs in brain. This will give insights into identifying novel molecular circuits in brain and provide an innovative approach to develop RNA based therapeutics for people suffering from brain disorders"

(PI: Dr Hu Qidong)


Daryl

"My area of interest is in RNA higher order structures and editing of RNA by ADARs. Currently I am working to elucidate the editing complementary sequence of AZIN1, and any possible therapeutics that can work to stop the development of hepatocellular carcinoma."

(PI: Dr Polly Chen)


Siqi

"My main research is on Oligodendrocytes and Retinal epithelial cells and does the role of juxtanodin expression abnormalities influences retinal disorders such as age-related macular degeneration."

(PI: A/P Liang FY)