The research emphasis of the laboratory is on translational clinical research which is geared towards patient care.
Major research themes of the laboratory are:
A/Prof Ti Lian Kah
Prof Lee Tat Leang
A/Prof Low Chiang Ming
Dr Tan Chee Kuan Francis (Senior Research Fellow)
Project involves the isolation of the interacting protein partners of a novel neuropeptide, designated p56, which has been isolated from the cerebrospinal fluid of chronic pain patients. The p56 peptide itself and its N-terminal end are found to be nociceptive whereas the C-terminal end is analgesic. Isolating its protein/receptor interacting partner will allow the understanding of the mechanism of action of p56, thereby allowing us to use it as a starting point for developing a new generation of analgesics.
Dr Li Chunmei (Sr Laboratory Executive)
Have more than 10 years of experience in research lab. Assisted research projects and gained proficiency in a range of laboratory techniques e.g. High Performance Liquid Chromatography (HPLC), cell culture, enzyme-linked immunosorbent assay (ELISA), radioimmunoassay (RIA) and animal work.
Ms Liu Weiling (Research Assistant / M.Sc Candidate)
Research interest is in the mechanistic pathway of chronic pain. Currently, I am investigating the pathophysiological mechanism of paclitaxel, a chemotherapeutic drug, in neuropathic pain using animal model. Concurrently, I am also discovering possible biomarkers and identifying the underlying mechanisms behind chronic osteoarthritic pain by studying the cerebrospinal fluid of chronic osteoarthritis patients.